Treatment of Aggressive NK-Cell Leukemia: A Case Report and Review of the Literature
Keyword(s):
Nk Cell
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Aggressive NK-cell leukemia is a rare malignancy with neoplastic proliferation of natural killer cells. It often presents with constitutional symptoms, a rapid declining clinical course, and a poor prognosis with a median survival of a few months. The disease is usually resistant to cytotoxic agents, and no treatment has emerged as the standard of care for these patients. We report a case of an 18-year-old male who obtains complete remission following two lines of combination chemotherapy. We describe in details our regimens for induction chemotherapy and perform a review of existing literature concerning treatment of aggressive NK-cell leukemia.
2013 ◽
Vol 52
(11)
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pp. 1235-1238
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2004 ◽
Vol 128
(2)
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pp. 210-213
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2003 ◽
Vol 127
(9)
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pp. e371-e373
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Keyword(s):
1950 ◽
Vol 32
(1)
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pp. 123
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