Topographic and anatomical characteristics of the bladder neck in early fetuses

Aim. To determine macro-and microscopic anatomical characteristics and the dynamics in topographic and anatomical interactions of the bladder neck with adjacent organs and structures at the beginning of the fetal period. Material and methods. The study was carried out on 70 fetal specimens. The age of subjects included in the study was determined according to the tables of B.M. Patten, B.P. Khvatova, Yu.N. Shapovalov based on measurements of the parietal-calcaneal length (PCL), taking into account the Instructions for determining the perinatal period, live birth, and stillbirth criteria, approved by Order of the Ministry of Health of Ukraine No. 179 dated March 29, 2006. To achieve this goal, the following methods of anatomical research were used: anthropometry - to determine the age of the studied subjects; injection of arterial vessels with subsequent dissection under the control of a microscope – to study the peculiarities of the blood supply to the vesicoureteral segment; radiography - to determine the skeletotopy of the vesicoureteral segment; macro-microscopy – to explore the anatomical relationships of the components of the vesicoureteral segment, their structure, shape, position; histological – to study the structure of the wall of the vesicoureteral segment; morphometry – to determine the morphometric parameters of the vesicoureteral segment; 3-D reconstruction method – to study the spatial structure of the vesicoureteral segment; statistical – to analyze and establish the reliability of differences in organometric parameters.Results. Skeletopically, the projection of the vesicoureteral junction of early fetuses is located at the level of the upper third of the pubic symphysis. At the beginning of the perinatal period in female fetuses, the bladder neck (6.9 ± 2.6 mm) is longer than in male fetuses (6.4 ± 2.4 mm). Based on the analysis and generalization of the research results, it is substantiated that at the beginning of the fetal period, the internal urethral sphincter can be formed: a) by two loops of the outer longitudinal layer; b) the ring of the circular layer and the front bundles of the outer longitudinal layer; c) anterior bundles of the outer longitudinal layer and transverse bundles of the inner longitudinal layer within the trigone of urinary bladder; d) a ring of the circular layer, thickened in the anterolateral sections.Conclusions. Considering the topographic and anatomical characteristics of the angio- and myoarchitectonics of the vesicoureteral segment, we believe that its role as a physiological sphincter of the lower urinary tract is provided by the interaction of the vascular and muscle components. The vascular component of the sphincter apparatus of the vesicoureteral segment is provided by veins located in three layers: 1) cavernous-like veins of the submucosa; 2) veins of the muscular membrane; 3) veins of tunica adventitia. The second anatomical component of the sphincter function of the vesicoureteral segment is the muscular one, represented by the internal urethral sphincter.

Biomechanical Tests and Finite Element Analyses of Pelvic Stability using Bilateral Single Iliac Screw with Different Channels in Lumbo-iliac Fixation

Background: In lumbo-iliac fixation, the iliac screw can be placed in a number of locations and directions, and multiple screws can be placed to enhance the fixation effect. At present, there is no uniform standard for the placement of single iliac screw. Biomechanical tests and finite element analyses were used to compare the effect of bilateral single iliac screw with three channels on pelvic stability in lumbo-iliac fixation, so as to provide a basis for determining the best single iliac screw channel.Methods: Five adult embalmed cadaver pelvic specimens were selected. Unstable Tile C1 pelvic injury model (pubic symphysis separation and left sacral Denis II fracture) was established. The pubic symphysis was fixed with five-hole reconstruction plate. Lumbo-iliac fixation for the treatment of pelvic posterior ring injury: three channels of bilateral single iliac screw (channel A from PSIS to AIIS, channel B from 1 cm medial and 1 cm caudal of PSIS to AIIS, channel C from 2 cm below PSIS to AIIS). At the same time, the finite element model of unstable pelvic posterior ring injury treated with lumbo-iliac fixation was established, which were used to analyze and explore the effect of bilateral single iliac screw with three channels on the biomechanical stability of the pelvis, including the stress distribution and the maximum Von Mises stress of internal fixation, vertebral body and ilium.Results: Biomechanical tests revealed that under vertical compression load, the compressive stiffness of pelvic specimens fixed with three channels of bilateral single iliac screw was lower than that of complete pelvic specimens (P < 0.05). The vertical displacement fixed by channel B was smaller than that fixed by channel A and channel C; however, there was no significant difference between channel B and channel A (P > 0.05). The compressive stiffness fixed by channel B was better than that fixed by channel A and channel C. Under torsional load, the torsional stiffness fixed by channel B was stronger than that fixed by channel A and channel C. Finite element analyses conformed that the maximum Von Mises stress of the internal fixator fixed in channel B under the conditions of vertical, forward bending, backward extension, left bending, left rotating and right bending were significantly lower than that fixed in channel A and channel C. Under various working conditions, the maximum Von Mises stress of the internal fixture of channel B was less than that of channel A. In terms of the maximum Von Mises stress of the vertebral body and iliac, compared with the other two iliac screw channels, the overall stress distribution fixed by channel B was more reasonable.Conclusions: Bilateral single iliac screw with three channels in lumbo-iliac fixation could effectively restore pelvic stability. The construct stiffness of the channel from 1cm medial and 1cm caudal of PSIS to AIIS is better than that of the other two channels. This channel has the advantages of good biomechanical stability, reasonable stress distribution, small maximum Von Mises stress of internal fixation, strong fatigue resistance and not easy to break screws and robs.

Fixation failure in patients with traumatic diastasis of pubic symphysis: impact of loss of reduction on early functional outcomes

Background Failure of fixation (FF) in pubic symphysis diastasis (SD) ranges between 12 and 75%, though whether it influences functional outcomes is still debated. The objective of this study is to evaluate the impact of anterior pelvic plate failure and loss of reduction on Majeed’s functional scores. Methods Single center retrospective review of consecutive patients with acute SD treated by means of anterior pubic plating. Thirty-seven patients with a mean age 45.7 ± 14.4 years were included. Demographics, AO classification, pelvic fixation and secondary procedures were recorded. Majeed’s functional scores at minimum 6 months follow-up were compared according to the presence of FF and loss of reduction. Results Fifteen patients presented FF. Eight presented an additional loss of symphyseal reduction. Mean Majeed´s score (MMS) in patients with and without FF was 64.4 ± 13.04 and 81.8 ± 15.65, respectively (p = 0.0012). Differences in MMS in patients without FF and those with FF and maintained or loss of anterior reduction were 11.3 [70.5 vs 81.8] (p = 0.092) and 22.7 [59.1 vs 81.8] (p = 0.001), respectively. Significant association of FF with AO classification was noted. (OR 12.6; p = 0.002). Conclusions Differences in MMS in the analyzed groups suggest that loss of reduction might be more relevant than failure of the anterior osteosynthesis in functional outcomes.

First case of the pigo-ischio-cephalopago deformation in a neonate of a gallube shark (Squalus acanthias- Linnaeus -1758) captured in Peruíbe, south coast of São Paulo, in the Cananeia -Iguape-Peruíbe environmental protection area

Connatural alterations can be deformations or malformations discovered in the embryonic development phase of the animal, which can disguise structures or roles of the systems. Congenital disorders can range from small changes, slight changes, serious adulterations and also genetic inconsistencies. There are no apparent defined reasons, and these changes may be caused by environmental and genetic factors. Pigopagus twins are joined at the back, have a coccyx, the gastrointestinal tract may have a single or separate rectum, a single bladder in some cases and obligatorily separate spinal cord and always with sharing of the pelvic bones. The ischiopagus are united by the ventral region from the navel to the pelvis, two sacrum and two pubic symphysis, in addition to a single gastrointestinal tract and a varied number of limbs. Reporting and discussing the morphological and anatomical deformities presented in a species of Squalus acanthias, recorded by LOPES in 2020, is a big step to better understand the anatomy and physiology of animals, which are considered the top of the food chain in the oceans and are in serious trouble. risk of extinction. RESUMO Alterações conaturais podem ser deformações ou más-formações descobertas na fase de desenvolvimento embrionário do animal, podendo disfarçar estruturas ou papéis dos sistemas. Os distúrbios congênitos podem ocorrer desde pequenas mudanças, alterações leves, adulterações sérias e também incoerências genéticas. Não existem motivos aparentes definidos, podendo estas alterações serem causados por fatores ambientais e genéticos. Os gêmeos Pigopagus são unidos pelo dorso, apresentam um coccix, o trato gastrointestinal pode apresentar reto único ou separado, bexiga única em alguns casos e obrigatoriamente medula espinhal separada e sempre com compartilhamento dos ossos pélvicos. Os isquiópagos apresentam-se unidos pela região ventral do umbigo à pelve, dois sacros e duas sínfises púpicas além de tratos gastrointestinal único e número de membros variados. Relatar e discutir as deformidades morfológicas e anatômicas apresentadas em uma especie de Squalus acanthias, registrada por LOPES em 2020, é um grande passo para entender melhor a anatomia e fisiologia de animais, que são considerados o topo da cadeia alimentar nos oceanos e correm um sério risco de extinção.

A clinical case of the uterine complete rupture along with the previous scar during pregnancy with atypical clinical features

This article presents an unusual case of rupture of the scarred uterus at 36-37 weeks of gestation. The patient presented with pain in the pubic and hip joint area, growing stronger while her walking, seated and changing position. No clinical manifestations of hemorrhagic shock were observed. External obstetric examination revealed a normotonic uterus and satisfactory fetus condition. Provocation tests were conducted to exclude subluxation of the pubic joint. Pubic symphysis diastasis palpation, long dorsal sacroiliac ligament palpation, P4 test, Patricks test, and the modified Trendelenburg test were negative. Pelvic examination revealed sharp pain in lower uterus segment. Ultrasound scan revealed deformation and thinning of the scar up to 1 mm, and no abnormalities in pubic symphysis. A threatening uterine rupture was diagnosed, and emergency cesarean section was performed. Intraoperative examination showed that the scar located in the lower segment consisted of connective tissue. In addition, there was a 4 5 cm scar defect with the overlying amniotic sac, no hemorrhage being noted. After removing the fetus, scar excision was performed. The uterine defect was repaired with a double layer running-locking suture. The patient was discharged from hospital on day 5 of postpartum period. The infant was exposed in the neonatal intensive care unit to provide an early developmental care.