scholarly journals The Application of a Contact Lens Sensor in Detecting 24-Hour Intraocular Pressure-Related Patterns

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Sarah C. Xu ◽  
Angela C. Gauthier ◽  
Ji Liu
Keyword(s):  
Intraocular Pressure ◽  
Disease Progression ◽  
Contact Lens ◽  
Open Angle Glaucoma ◽  
Normal Tension Glaucoma ◽  
Angle Closure ◽  
Blink Rate ◽  
Disease States ◽  
Wide Range ◽  
Contact Lens Sensor

Glaucoma is one of the leading causes of blindness worldwide. Recent studies suggest that intraocular pressure (IOP) fluctuations, peaks, and rhythm are important factors in disease advancement. Yet, current glaucoma management remains hinged on single IOP measurements during clinic hours. To overcome this limitation, 24-hour IOP monitoring devices have been employed and include self-tonometry, permanent IOP, and temporary IOP monitoring. This review discusses each IOP measuring strategy and focuses on the recently FDA-approved contact lens sensor (CLS). The CLS records IOP-related ocular patterns for 24 hours continuously. Using the CLS, IOP-related parameters have been found to be associated with the rate of visual field progression in primary open-angle glaucoma, disease progression in primary angle-closure glaucoma, and various clinical variables in ocular hypertension. The CLS has been used to quantify blink rate and limbal strain and measure the circadian rhythm in a variety of disease states including normal-tension glaucoma and thyroid eye disease. The effects of various IOP-lowering interventions were also characterized using the CLS. CLS provides a unique, safe, and well-tolerated way to study IOP-related patterns in a wide range of disease states. IOP-related patterns may help identify patients most at risk for disease progression and assist with the development of tailored treatments.

Comparison of intraocular pressure fluctuation before and after cataract surgeries in normal-tension glaucoma patients

2018 ◽  
Vol 29 (5) ◽  
pp. 516-523 ◽  
Author(s):  
Naoki Tojo ◽  
Mitsuya Otsuka ◽  
Atsushi Hayashi
Keyword(s):  
Regression Analysis ◽  
Intraocular Pressure ◽  
Cataract Surgery ◽  
Contact Lens ◽  
Pressure Fluctuations ◽  
Normal Tension Glaucoma ◽  
Open Label ◽  
Before And After ◽  
Contact Lens Sensor ◽  
Harmonic Regression

Purpose: Cataract surgeries have been shown to reduce intraocular pressure. We used a Sensimed Triggerfish® contact lens sensor to compare intraocular pressure levels and their fluctuation between before and after cataract surgeries in patients with normal-tension glaucoma. Methods: This was a prospective open-label study. Thirteen patients with normal-tension glaucoma were included. All patients underwent a 1-month washout and discontinued glaucoma medications during this study. In each eye, intraocular pressure fluctuations over 24 h were measured with the contact lens sensor before and at 3 months after the cataract surgery. We compared intraocular pressure levels and their fluctuation between before and after cataract surgeries. We used two approaches to evaluate the amplitude of intraocular pressure fluctuations: dual-harmonic regression analysis, and measurement of the difference between the maximum and the minimum value. Results: The mean pre-operative intraocular pressure was 14.7 ± 2.2 mm Hg and mean post-operative intraocular pressure was 11.4 ± 2.2 mm Hg. Cataract surgery significantly decreased intraocular pressure (p = 0.0005). In both methods, the post-operative fluctuations in intraocular pressure over 24 h were significantly smaller than their pre-operative counterparts (dual-harmonic regression analysis: p = 0.0171; difference between the maximum and the minimum: p = 0.0398). Conclusion: Cataract surgery decreased both intraocular pressure values and intraocular pressure fluctuations in normal-tension glaucoma patients.

scholarly journals Circadian intraocular pressure patterns in healthy subjects, primary open angle and normal tension glaucoma patients with a contact lens sensor

2014 ◽  
Vol 93 (1) ◽  
pp. e14-e21 ◽  
Author(s):  
Luca Agnifili ◽  
Rodolfo Mastropasqua ◽  
Paolo Frezzotti ◽  
Vincenzo Fasanella ◽  
Ilaria Motolese ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Contact Lens ◽  
Healthy Subjects ◽  
Normal Tension Glaucoma ◽  
Open Angle ◽  
Contact Lens Sensor

scholarly journals Our Experience With Micropulse Cyclophotocoagulation in the Therapy Of Glaucoma

2020 ◽  
Vol 76 (1) ◽  
pp. 29-34
Author(s):  
Elena Nutterová ◽  
Šárka Pitrová ◽  
Ján Lešták
Keyword(s):  
Intraocular Pressure ◽  
Laser Energy ◽  
Open Angle Glaucoma ◽  
Neovascular Glaucoma ◽  
Normal Tension Glaucoma ◽  
Angle Closure ◽  
Pigmentary Glaucoma ◽  
Laser Iridotomy ◽  
Primary Angle Closure Glaucoma ◽  
Retrospective Assessment

The objective of this study was a retrospective assessment of two-year experience with micropulse cyclophotocoagulation (MP CPC) in the therapy of various types of glaucoma. Material and method: The cohort of patients consisted of 47 people, out of which 16 men and 31 women. An average age of males was 58.9 years (the range from 35 to 78 years), and an average age of females was 64.7 years (the range from 33 to 86 years). Both eyes were treated in three patients, and therefore the total number of assessed eyes was 50. Patients who underwent the therapy were in different stages of glaucoma disease, with various types of primary and secondary glaucoma. Most of the patients were those with primary open angle glaucoma (POAG): 26 patients, followed by patients with secondary pseudoexfoliative glaucoma (PEXG): 9 patients; diagnoses of the remaining patients: 4 patients – secondary pigmentary glaucoma (PG), 3 patients - primary angle closure glaucoma (PACG), 2 patients normal tension glaucoma (NTG), 3 patients - Posner-Schlossman syndrome, 1 patient - Cogan-Reese syndrome, 1 patient - neovascular glaucoma and 1 patient – secondary traumatic glaucoma. On the operated eye prior to the surgery 3 patients underwent laser iridotomy, 4 patients trabeculectomy, 4 patients EX-PRESS® implant, 3 patients EX-PRESS® implant and trabeculectomy and 1 patient transscleral cyclophotocoagulation. During surgery we opted for from 2,000 to 2,250 mW infrared laser with 810 nm wavelength which uses a micropulse system of laser energy emission. For the procedure we used a new MP3 application probe. 30% drop in intraocular pressure (IOP) compared to the baseline IOP values was set as a success. Results: Our results correlated with the most of available studies when we achieved drop in the values of intraocular pressure by the minimum of 30% in 53.4% of the eyes. The effect of therapy failed in 9 eyes (18%) where we subsequently selected a different therapeutic procedure. Conclusion: MP CPC is a non-incisional laser treatment with minimum complications. It is characterized by a high safety profile and predictability of results. In our study we achieved drop in the values of intraocular pressure by the minimum of 30% in 53.4% of treated eyes. Its use is not limited by the type of glaucoma disease. In the event of insufficient effect, it may be repeated.

scholarly journals EFFECTIVENESS OF MICROPULSE MP3 CYCLODIODE LASER IN CONTROLLING INTRAOCULAR PRESSURE WITHOUT ACETAZOLAMIDE

2020 ◽  
Vol 35 (4) ◽  
pp. 223-228
Author(s):  
Dr Sahira Wasim
Keyword(s):  
Intraocular Pressure ◽  
Open Angle Glaucoma ◽  
Case Series ◽  
Normal Tension Glaucoma ◽  
Angle Closure ◽  
P Value ◽  
Fisher Exact Test ◽  
Safe Alternative ◽  
Case Series Study ◽  
Department Of Ophthalmology

ABSTRACT Background: Glaucoma is a 2ndleading cause of irreversible blindness worldwide. Primary surgical procedures include trabeculectomy with or without anti-metabolites, as well as glaucoma drainage devices. Cycloablation lowers IOP by destruction of ciliary body epithelium and stroma, thus reducing aqueous production. Objective: To determine effectiveness of micropulse mp3 cyclodiode laser in controlling intraocular pressure without acetazolamide. Study design: Descriptive case series study Place and duration of study: Department of Ophthalmology, Liaquat National Hospital, Karachi for 6 months duration Material and Methods: In our study total 98 patients of either gender with age 20 to 50 years, following inclusion criteria (Chronic open angle glaucoma, Neovascular, Refractory, Uveitic, Trauma induced glaucoma, and Post vitrectomy induced glaucoma) and exclusion criteria (Primary angle closure and Normal tension glaucoma) were included. Descriptive statistics were calculated. Frequencies and percentages were computed for qualitative variables. Quantitative variables were presented as mean±standard deviation. The mean baseline IOP was compared with mean IOP of 3 months using student t-test. Effect modifiers were controlled through stratification. Fisher exact test was used to see the association of effectiveness with stratified groups. P-value ≤0.05 was considered as significant. Results: Among total 98 patients, 63.3% were male and 36.7% were female. Mean age was 48.46±13.39 years. The effectiveness of Micropulse Mp3 Cyclodiode Laser was observed in 85.7% cases. Significant mean difference was found for pre-op IOP with IOP after 3 months for right eye and left eye. Insignificant association of effectiveness was found with gender, age, type and procedure. Conclusion: Micro pulse MP3 appears to be a promising, safe alternative procedure with potential advantages as well as high level of effectiveness. Keywords: Micropulse Mp3 Cyclodiode Laser, Intraocular Pressure, Acetazolamide

scholarly journals Relationship between nocturnal intraocular pressure-related peak recorded by contact lens sensor and disease progression in treated glaucomatous eyes

2020 ◽  
Vol 68 (11) ◽  
pp. 2427
Author(s):  
Deepti Mittal ◽  
Suneeta Dubey ◽  
Saptarshi Mukherjee ◽  
Madhu Bhoot ◽  
YadunandanP Gupta
Keyword(s):  
Intraocular Pressure ◽  
Disease Progression ◽  
Contact Lens ◽  
Contact Lens Sensor

The Fluctuation of Intraocular Pressure Measured by a Contact Lens Sensor in Normal-Tension Glaucoma Patients and Nonglaucoma Subjects

2017 ◽  
Vol 26 (3) ◽  
pp. 195-200 ◽  
Author(s):  
Naoki Tojo ◽  
Shinya Abe ◽  
Masaaki Ishida ◽  
Takaaki Yagou ◽  
Atsushi Hayashi
Keyword(s):  
Intraocular Pressure ◽  
Contact Lens ◽  
Normal Tension Glaucoma ◽  
Contact Lens Sensor

scholarly journals The Use of Anterior-Segment Optical-Coherence Tomography for the Assessment of the Iridocorneal Angle and Its Alterations: Update and Current Evidence

2021 ◽  
Vol 10 (2) ◽  
pp. 231
Author(s):  
Giacinto Triolo ◽  
Piero Barboni ◽  
Giacomo Savini ◽  
Francesco De Gaetano ◽  
Gaspare Monaco ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Clinical Relevance ◽  
Anterior Segment ◽  
Angle Closure ◽  
Current Evidence ◽  
Optical Coherence ◽  
Iridocorneal Angle ◽  
Wide Range

The introduction of anterior-segment optical-coherence tomography (AS-OCT) has led to improved assessments of the anatomy of the iridocorneal-angle and diagnoses of several mechanisms of angle closure which often result in raised intraocular pressure (IOP). Continuous advancements in AS-OCT technology and software, along with an extensive research in the field, have resulted in a wide range of possible parameters that may be used to diagnose and follow up on patients with this spectrum of diseases. However, the clinical relevance of such variables needs to be explored thoroughly. The aim of the present review is to summarize the current evidence supporting the use of AS-OCT for the diagnosis and follow-up of several iridocorneal-angle and anterior-chamber alterations, focusing on the advantages and downsides of this technology.

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