Paraneoplastic Dermatomyositis Associated with Metastatic Seminoma

We report the first case in Japan of paraneoplastic dermatomyositis with pure seminoma, a tumor that extremely rarely accompanies dermatomyositis. The patient presented to the hospital with muscle weakness and erythema and was diagnosed with dermatomyositis from skin biopsy. Routine radiological screening revealed testicular tumor and massive lymph node metastases. We initially performed orchiectomy along with conventional immunotherapy. However, muscle weakness gradually worsened, and he eventually showed dysphagia and forced respiration and became bedridden. Although he seemed close to being too unstable to tolerate further treatment, we started carefully adjusted chemotherapy comprising 4 courses of etoposide plus cisplatin, which proved highly successful. Lymph node metastases completely disappeared and swallowing and respiration fully normalized after completing chemotherapy. We believe that this clinical success was due to our decision to initiate chemotherapy even in such a weak patient.

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Inguinal Lymph Node Metastases from Testicular Tumor

The Journal of Urology ◽

10.1016/s0022-5347(17)47033-9 ◽

1985 ◽

Vol 134 (1) ◽

pp. 144-145 ◽

Cited By ~ 6

Author(s):

Moshe Stein ◽

Marianna Steiner ◽

Harry Suprun ◽

Eliezer Robinson

Keyword(s):

Lymph Node ◽

Lymph Node Metastases ◽

Inguinal Lymph Node ◽

Testicular Tumor ◽

Node Metastases

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A case of contralateral inguinal lymph node metastases from breast cancer

Surgical Case Reports ◽

10.1186/s40792-021-01181-z ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Takeo Kimoto ◽

Norio Kohno ◽

Akiko Okamoto ◽

Kyosuke Ota ◽

Takafumi Tani ◽

...

Keyword(s):

Breast Cancer ◽

Lymph Node ◽

Lymph Node Metastases ◽

Inguinal Lymph Node ◽

English Literature ◽

Joint Disease ◽

Internal Mammary Nodes ◽

First Case ◽

Abdominal Operations ◽

Node Metastases

Abstract Background Breast cancer is well known to tends to invade through the lymphatic chains mainly to the axillary and subclavian nodes or occasionally to the internal mammary nodes. However, inguinal lymph node metastasis from breast cancer is extremely rare. Case presentation We have experienced a case of an 82-year-old woman showing left inguinal lymph node metastases from right breast cancer. Previously, she had received five times abdominal operations and left artificial bone head replacement for metamorphous hip-joint disease. Although the metastases were firstly detected 46 months after the breast surgery, they had already existed at the time of the breast operation, which was retrospectively re-evaluated by CT examination. The progression pattern of inguinal lymph node metastases had much correlated with that of the breast cancer. She underwent inguinal lymph node dissections. Pathological findings revealed them being compatible with breast cancer origin. Conclusions This is the sixth case having been reported in English literature. Besides, this is the first case showing the contralateral spread to the primary breast cancer. One of the causes of this complex metastatic pattern is thought be ascribed to the previously performed prolific abdominal operations.

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Juxta-adrenal malignant schwannoma with lymph node metastases

Canadian Urological Association Journal ◽

10.5489/cuaj.1217 ◽

2013 ◽

Vol 7 (9-10) ◽

pp. 657 ◽

Cited By ~ 5

Author(s):

Yu Seob Shin ◽

Hyung Jin Kim ◽

Myung Ki Kim

Keyword(s):

Lymph Node ◽

Lymph Node Metastases ◽

Adrenal Mass ◽

Neural Crest Cell ◽

Malignant Schwannoma ◽

Metabolic Evaluation ◽

Rare Tumour ◽

First Case ◽

Imaging Results ◽

Node Metastases

Juxta-adrenal malignant schwannoma is a very rare tumour of neural crest cell origin. A 69-year-old woman visited for proper management of incidentally detected adrenal mass as part of a dyspepsia workup. Metabolic evaluation was unremarkable and imaging results suggested a malignant adrenal mass with lymphnode metastases. The patient underwent a left adrenalectomy with para-aortic lymphadenectomy. The diagnosis and its origin was confirmed by histologic and immunohistochemical studies. We report the first case of juxta-adrenal malignant schwannoma with lymph node metastases, and review the literature on this rare tumour.

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Ectopic adrenocortical carcinoma located in the ovary

Acta Endocrinologica ◽

10.1530/eje-16-0224 ◽

2016 ◽

Vol 175 (4) ◽

pp. K17-K23 ◽

Cited By ~ 7

Author(s):

Farida Chentli ◽

Nadia Terki ◽

Said Azzoug

Keyword(s):

Lymph Node ◽

Lymph Node Metastases ◽

Ovarian Tumor ◽

Histological Study ◽

Large Mass ◽

Lower Abdomen ◽

First Case ◽

Abdomen Ct ◽

Node Metastases ◽

The Right

Aim Ovarian corticosteroid-producing tumors are exquisitely rare. Our aim was to describe the first case observed in our practice. Case history A 34-year-old female was referred for Cushing’s syndrome (CS) occurring in the postpartum period. Clinical examination showed severe CS with diabetes mellitus, hypertension, and a large mass in the right lower abdomen. Biochemistry demonstrated corticotropin (ACTH)-independent CS (cortisol=1900ng/mL (n=50–250), ACTH<10pg/mL (n=20–46)) with estradiol and testosterone overproduction. Investigations Abdomen CT scan revealed a 14cm right ovarian mass and small adrenal glands. Surgical exploration found the ovarian tumor with hemoperitoneum and enlarged lymph nodes. Histological study confirmed adrenocortical tumor located in the ovary with a Weiss score >5, associated with peritoneal and lymph node metastases. Immunohistochemical staining was positive for inhibin-α, melan-A, and SF1, demonstrating tissue of adrenal origin. After surgery, plasma glucose level spontaneously returned to normal. However, the patient died on the second post-surgical day due to catastrophic pulmonary embolism. Conclusion In this reported case, clinical, hormonal, histological, and immunohistochemical findings confirmed a cortisol and sex hormone-producing ovarian tumor with peritoneal and lymph node metastases, a very rare but important condition to recognize.

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