Ectopic adrenocortical carcinoma located in the ovary

Aim Ovarian corticosteroid-producing tumors are exquisitely rare. Our aim was to describe the first case observed in our practice. Case history A 34-year-old female was referred for Cushing’s syndrome (CS) occurring in the postpartum period. Clinical examination showed severe CS with diabetes mellitus, hypertension, and a large mass in the right lower abdomen. Biochemistry demonstrated corticotropin (ACTH)-independent CS (cortisol=1900ng/mL (n=50–250), ACTH<10pg/mL (n=20–46)) with estradiol and testosterone overproduction. Investigations Abdomen CT scan revealed a 14cm right ovarian mass and small adrenal glands. Surgical exploration found the ovarian tumor with hemoperitoneum and enlarged lymph nodes. Histological study confirmed adrenocortical tumor located in the ovary with a Weiss score >5, associated with peritoneal and lymph node metastases. Immunohistochemical staining was positive for inhibin-α, melan-A, and SF1, demonstrating tissue of adrenal origin. After surgery, plasma glucose level spontaneously returned to normal. However, the patient died on the second post-surgical day due to catastrophic pulmonary embolism. Conclusion In this reported case, clinical, hormonal, histological, and immunohistochemical findings confirmed a cortisol and sex hormone-producing ovarian tumor with peritoneal and lymph node metastases, a very rare but important condition to recognize.

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A Study on the Lymph Node Metastases of the Right Side Colon Cancer in Relation to the Location of Cancer and the Arterial Supply.

The Japanese Journal of Gastroenterological Surgery ◽

10.5833/jjgs.26.2784 ◽

1993 ◽

Vol 26 (12) ◽

pp. 2784-2792

Author(s):

Shigeki Takashima ◽

Fujio Tomita ◽

Takayoshi Akiyama ◽

Harukimi Gotohda ◽

Masato Kiriyama ◽

...

Keyword(s):

Colon Cancer ◽

Lymph Node ◽

Lymph Node Metastases ◽

Arterial Supply ◽

Node Metastases ◽

The Right

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Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer

Case Reports in Endocrinology ◽

10.1155/2017/7956726 ◽

2017 ◽

Vol 2017 ◽

pp. 1-3

Author(s):

Joji Kawabe ◽

Shigeaki Higashiyama ◽

Mitsuharu Sougawa ◽

Atsushi Yoshida ◽

Kohei Kotani ◽

...

Keyword(s):

Lymph Node ◽

Lymph Node Metastasis ◽

Lymph Node Metastases ◽

Parapharyngeal Space ◽

Target Volume ◽

Stereotactic Radiation ◽

Node Metastasis ◽

Prescription Dose ◽

Node Metastases ◽

The Right

A woman in her 60s presented with a recurrent lymph node metastasis from a papillary thyroid carcinoma in the right parapharyngeal space. She had already undergone total thyroidectomy, five resections for cervical lymph node metastases, and right carotid rebuilding. Surgical resection of the current metastasis was impossible. 131I-radioiodine therapy (RIT) with 3.7 GBq 131I was not effective; therefore, stereotactic radiation therapy (SRT) using a CyberKnife radiotherapy system was scheduled. The prescription dose was 21 Gy, and a dose covering 95% of the planning target volume (PTV) in three fractions was administered. The PTV was 4,790 mm3. Follow-up magnetic resonance imaging conducted 3 and 12 months after the SRT demonstrated a remarkable and gradual reduction of the recurrent lymph node metastasis in the right parapharyngeal space and no evidence of recurrence. For multidisciplinary therapy of unresectable and/or RIT unresponsive locoregional lymph node metastases and recurrences of DTC, SRT using the CyberKnife system should be considered.

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Adenocarcinoma of the Right Breast in a Man with Intellectual Disability

Case Reports in Oncological Medicine ◽

10.1155/2013/968035 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Daniel Satgé ◽

Bernard Leduc ◽

Fernand Raffi ◽

Etienne Roux

Keyword(s):

Breast Cancer ◽

Lymph Node ◽

Intellectual Disability ◽

Breast Carcinoma ◽

Cancer Treatment ◽

Lymph Node Metastases ◽

Good Health ◽

Moderate Intellectual Disability ◽

Node Metastases ◽

The Right

A 64-year-old man with moderate intellectual disability developed a large right breast carcinoma with lymph node metastases. Cancer treatment is often difficult in persons with intellectual disability. However, the patient could be treated according to the current protocols with surgery, chemotherapy, and radiotherapy. He is alive and in good health two years after discovery of his tumor. Although breast cancer is estimated as frequent in women with intellectual disability as it is in nondisabled women, our patient is the second man with intellectual disability reported with a breast carcinoma.

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Possible Metaplastic Origin of Lymph Node “Metastases” in Serous Ovarian Tumor of Low Malignant Potential (Borderline Serous Tumor)

Gynecologic Oncology ◽

10.1006/gyno.1995.9955 ◽

1995 ◽

Vol 59 (3) ◽

pp. 394-397 ◽

Cited By ~ 38

Author(s):

Nicholas Kadar ◽

Martin Krumerman

Keyword(s):

Lymph Node ◽

Lymph Node Metastases ◽

Ovarian Tumor ◽

Malignant Potential ◽

Low Malignant Potential ◽

Node Metastases ◽

Serous Tumor

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A case of Extramammary Paget's disease with bilateral inguinal lymph node metastases showing purpuric erythema on the lower abdomen and left thigh.

Skin Cancer ◽

10.5227/skincancer.17.161 ◽

2002 ◽

Vol 17 (2) ◽

pp. 161-165

Author(s):

Yasuhiro ITO ◽

Takashi WADA ◽

Kazuhiro ASANO ◽

Hidetoshi TAKAHASHI ◽

Hiroshi YOSHIDA ◽

...

Keyword(s):

Lymph Node ◽

Lymph Node Metastases ◽

Inguinal Lymph Node ◽

Paget’S Disease ◽

Paget's Disease ◽

Left Thigh ◽

Extramammary Paget’S Disease ◽

Lower Abdomen ◽

Node Metastases ◽

Extramammary Paget's Disease

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Apocrine Adenocarcinoma of the Vulva: A Case Report and Review of the Literature

Case Reports in Obstetrics and Gynecology ◽

10.1155/2016/1712404 ◽

2016 ◽

Vol 2016 ◽

pp. 1-4

Author(s):

Kohei Aoyama ◽

Hiroshi Matsushima ◽

Morio Sawada ◽

Taisuke Mori ◽

Satoru Yasukawa ◽

...

Keyword(s):

Lymph Node ◽

Lymph Node Metastases ◽

Inguinal Lymph Node ◽

Primary Source ◽

Pelvic Lymphadenectomy ◽

Japanese Woman ◽

Apocrine Adenocarcinoma ◽

Node Metastases ◽

Systemic Examination ◽

The Right

Primary vulvar adenocarcinomas are very rare. We describe the rare case of primary vulvar apocrine adenocarcinoma, a histologically rare subtype of vulvar adenocarcinoma. A 57-year-old Japanese woman presented with an enlarging vulvar mass. A dark-red, hemorrhagic, ulcerated tumor was on the right side of the anterior labial commissure measuring approximately3.5×3.5 cm. Preoperative biopsy showed poorly differentiated carcinoma with partial differentiation to adenocarcinoma. Systemic examination revealed lymph node metastases in both inguinal regions and no other primary source. We performed radical vulvectomy and bilateral inguinal and pelvic lymphadenectomy. Histopathologic diagnosis was apocrine adenocarcinoma of the vulva with inguinal lymph node metastases, pT1bN2bM0. Surgical margins were negative. The patient received no adjuvant chemotherapy or radiation. Inguinal lymph node recurrence occurred after six months. Reresection and adjuvant tomotherapy were performed. After a further 12 months of observation, no rerecurrence was observed. The patient is now on follow-up.

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Paraneoplastic Dermatomyositis Associated with Metastatic Seminoma

Case Reports in Urology ◽

10.1155/2016/7050981 ◽

2016 ◽

Vol 2016 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Hidekazu Yoshie ◽

Ryuto Nakazawa ◽

Wataru Usuba ◽

Hiroya Kudo ◽

Yuichi Sato ◽

...

Keyword(s):

Lymph Node ◽

Skin Biopsy ◽

Muscle Weakness ◽

Lymph Node Metastases ◽

Clinical Success ◽

Testicular Tumor ◽

First Case ◽

Node Metastases ◽

Pure Seminoma

We report the first case in Japan of paraneoplastic dermatomyositis with pure seminoma, a tumor that extremely rarely accompanies dermatomyositis. The patient presented to the hospital with muscle weakness and erythema and was diagnosed with dermatomyositis from skin biopsy. Routine radiological screening revealed testicular tumor and massive lymph node metastases. We initially performed orchiectomy along with conventional immunotherapy. However, muscle weakness gradually worsened, and he eventually showed dysphagia and forced respiration and became bedridden. Although he seemed close to being too unstable to tolerate further treatment, we started carefully adjusted chemotherapy comprising 4 courses of etoposide plus cisplatin, which proved highly successful. Lymph node metastases completely disappeared and swallowing and respiration fully normalized after completing chemotherapy. We believe that this clinical success was due to our decision to initiate chemotherapy even in such a weak patient.

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A case of contralateral inguinal lymph node metastases from breast cancer

Surgical Case Reports ◽

10.1186/s40792-021-01181-z ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Takeo Kimoto ◽

Norio Kohno ◽

Akiko Okamoto ◽

Kyosuke Ota ◽

Takafumi Tani ◽

...

Keyword(s):

Breast Cancer ◽

Lymph Node ◽

Lymph Node Metastases ◽

Inguinal Lymph Node ◽

English Literature ◽

Joint Disease ◽

Internal Mammary Nodes ◽

First Case ◽

Abdominal Operations ◽

Node Metastases

Abstract Background Breast cancer is well known to tends to invade through the lymphatic chains mainly to the axillary and subclavian nodes or occasionally to the internal mammary nodes. However, inguinal lymph node metastasis from breast cancer is extremely rare. Case presentation We have experienced a case of an 82-year-old woman showing left inguinal lymph node metastases from right breast cancer. Previously, she had received five times abdominal operations and left artificial bone head replacement for metamorphous hip-joint disease. Although the metastases were firstly detected 46 months after the breast surgery, they had already existed at the time of the breast operation, which was retrospectively re-evaluated by CT examination. The progression pattern of inguinal lymph node metastases had much correlated with that of the breast cancer. She underwent inguinal lymph node dissections. Pathological findings revealed them being compatible with breast cancer origin. Conclusions This is the sixth case having been reported in English literature. Besides, this is the first case showing the contralateral spread to the primary breast cancer. One of the causes of this complex metastatic pattern is thought be ascribed to the previously performed prolific abdominal operations.

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Juxta-adrenal malignant schwannoma with lymph node metastases

Canadian Urological Association Journal ◽

10.5489/cuaj.1217 ◽

2013 ◽

Vol 7 (9-10) ◽

pp. 657 ◽

Cited By ~ 5

Author(s):

Yu Seob Shin ◽

Hyung Jin Kim ◽

Myung Ki Kim

Keyword(s):

Lymph Node ◽

Lymph Node Metastases ◽

Adrenal Mass ◽

Neural Crest Cell ◽

Malignant Schwannoma ◽

Metabolic Evaluation ◽

Rare Tumour ◽

First Case ◽

Imaging Results ◽

Node Metastases

Juxta-adrenal malignant schwannoma is a very rare tumour of neural crest cell origin. A 69-year-old woman visited for proper management of incidentally detected adrenal mass as part of a dyspepsia workup. Metabolic evaluation was unremarkable and imaging results suggested a malignant adrenal mass with lymphnode metastases. The patient underwent a left adrenalectomy with para-aortic lymphadenectomy. The diagnosis and its origin was confirmed by histologic and immunohistochemical studies. We report the first case of juxta-adrenal malignant schwannoma with lymph node metastases, and review the literature on this rare tumour.

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