scholarly journals Squamous Cell Cancer Arising in an African American Male Cheek from Discoid Lupus: A Rare Case and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-3
Author(s):  
Emanuel A. Shapera ◽  
Paul D. Kim

A 50-year-old African American male with Discoid Lupus Erythematosus (DLE) presented to the dermatology clinic for a rapidly enlarging left cheek mass. The mass failed to resolve with conservative measures. A biopsy revealed poorly differentiated Squamous Cell Carcinoma (SCC). He was referred to Head and Neck Surgery and successfully underwent a resection with free flap reconstruction. Postoperatively he did well. Squamous cell skin carcinomas arising from lesions of Discoid Lupus are rare and aggressive tumors with greater likelihood of metastases. Cases have been reported among patients with different clinical characteristics; we present a rare case arising in an African American male on the face and involving the ear.

1968 ◽  
Vol 42 (5) ◽  
pp. 497-499 ◽  
Author(s):  
RICHARD A. MLADICK ◽  
KENNETH L. PICKRELL ◽  
FRANK L. THORNE ◽  
JOHN H. HALL

2020 ◽  
Vol 96 (4) ◽  
pp. 60-66
Author(s):  
Valeriy V. Dubensky ◽  
Elizaveta G. Nekrasova ◽  
Olga A. Alexandrova ◽  
Ekaterina S. Muraveva

A rare case of a combination of vulgar psoriasis and squamous cell carcinoma of the penis in a patient with discoid lupus erythematosus is described. The literature data on the comorbidity of dermatoses are given.


Lupus ◽  
2020 ◽  
Vol 29 (6) ◽  
pp. 644-648 ◽  
Author(s):  
Leah Cohen ◽  
Vidhi Shah ◽  
Pei-Ling Chen ◽  
Jane Messina ◽  
Lucia Seminario-Vidal

Hypertrophic lupus erythematosus is a variant of discoid lupus erythematosus, which manifests as verrucous plaques and/or keratoacanthoma-like nodules on the face and arms. Diagnosis and treatment of hypertrophic lupus erythematosus can be challenging as it can resemble cutaneous squamous cell carcinoma clinically and histopathologically. Furthermore, cutaneous squamous cell carcinoma is a known complication of discoid lupus erythematosus. We present a diagnostically challenging case of a patient with a rapidly enlarging rhinophymatous mass and multiple keratoacanthoma-like lesions of the bilateral upper extremities whose work-up was initially equivocal. CD123 staining helped to elucidate a final diagnosis of cutaneous squamous cell carcinoma arising in a background of occult hypertrophic lupus erythematosus.


2008 ◽  
Vol 70 (1) ◽  
pp. 23-26
Author(s):  
Yoko YOKOYAMA ◽  
Fumihide OGAWA ◽  
Kazuhiro KOMURA ◽  
Emiko TAKEISHI ◽  
Shinichi SATO

We report a very rare case of squamous cell cancer of the right foot which had metastasize to the ipsilateral popliteal lymph node after initial diagnosis and treatment for the loco-regional disease.


2004 ◽  
Vol 31 (1) ◽  
pp. 73-75 ◽  
Author(s):  
Shigeto Matsushita ◽  
Tsuyoshi Ishihara ◽  
Toshiro Kageshita ◽  
Kiyofumi Egawa ◽  
Taiga Miyake ◽  
...  

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