Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review

Background.Primary splenic angiosarcoma is a very rare mesenchymal malignant tumor associated with a poor prognosis due to its high metastatic potential. This disease can be easily neglected and spontaneous splenic rupture is a frequent manifestation at the time of diagnosis leading to a poor outcome because of peritoneal dissemination.Case Presentation.We describe the case of a 49-year-old man who presented with asthenia, left upper quadrant abdominal pain, and anemia. Computerized tomography scan showed an enlarged spleen with no nodules and a nontraumatic rupture of the splenic capsule. Splenectomy was performed on account of the severe anemia and histopathology examination showed a primary angiosarcoma.Conclusions.Splenic angiosarcoma should be considered as one of the differential diagnoses in patients with nontraumatic spleen rupture and a specific previous medical history. Regrettably, splenectomy allows for a definitive diagnosis but not a curative treatment.

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GCT of knee treated with modular prosthesis-case presentation

Romanian Journal of Orthopaedic Surgery and Traumatology ◽

10.2478/rojost-2019-0004 ◽

2019 ◽

Vol 2 (1) ◽

pp. 18-22

Author(s):

Alexandru Papuc ◽

Ioan Mihai Japie ◽

Traian Ciobanu ◽

Octavian Nutiu ◽

Dragos Radulescu ◽

...

Keyword(s):

Bone Tumors ◽

Benign Tumor ◽

Distal Femur ◽

Proximal Tibia ◽

Metastatic Potential ◽

Left Knee ◽

Case Presentation ◽

Previous Medical History ◽

Malignancy Potential

AbstractThe GCT is an aggressive benign tumor with metastatic potential, most often within the lungs in 2-3% of the patients. It makes about 5% of total bone tumors and about 15% of total benign bone tumors.The maximum incidence occurs between 30 and 40 years old, most frequently affecting the long bones epiphysis (distal femur, proximal tibia, and distal radius).We report the case of a 50-year-old female, with no previous medical history, admitted in the emergency department (ED) for significant pain and functional impairment of the left knee. Clinical examination and imaging tests established the diagnosis of distal femoral tumor.The patient underwent surgical segmental resection of the tumor within oncological limits and subsequent arthroplasty with cemented modular tumoral prosthesis was performed.Even if the GCT is a benign tumor, it has an aggressive behavior and malignancy potential with an important impact on quality of life. Due to localization, this type of tumor can quickly manifest clinically, which allows an early diagnosis and a less invasive surgical technique.

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Unexpected death due to spontaneous splenic rupture: A rare case in splenic angiosarcoma

Legal Medicine ◽

10.1016/j.legalmed.2020.101785 ◽

2020 ◽

Vol 47 ◽

pp. 101785

Author(s):

Shuquan Zhao ◽

Longlong Zhu ◽

Fang Tong ◽

Lopsong Tinzin ◽

Fang Huang ◽

...

Keyword(s):

Rare Case ◽

Splenic Rupture ◽

Spontaneous Splenic Rupture ◽

Unexpected Death ◽

Splenic Angiosarcoma

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Primary Angiosarcoma of the Spleen: An Oncological Enigma

Case Reports in Oncological Medicine ◽

10.1155/2014/193036 ◽

2014 ◽

Vol 2014 ◽

pp. 1-4 ◽

Cited By ~ 6

Author(s):

Myoteri Despoina ◽

Dellaportas Dionysios ◽

Ayiomamitis Georgios ◽

Strigklis Konstantinos ◽

Kouroumpas Efstratios ◽

...

Keyword(s):

Histopathological Examination ◽

Abdominal Mass ◽

Correct Diagnosis ◽

Histopathological Diagnosis ◽

Case Presentation ◽

Male Predominance ◽

Primary Angiosarcoma ◽

Left Pleural Effusion ◽

Disease Site ◽

Splenic Angiosarcoma

Introduction. Primary splenic angiosarcoma is an extremely unusual neoplasm originating from sinusoidal vascular endothelium. Surgical extirpation is the mainstay of treatment of this highly malignant disease.Case Presentation. An 82-year-old woman was admitted with left pleural effusion and a palpable left upper quadrant abdominal mass, secondary to splenomegaly by two large splenic tumors. Classic open splenectomy was performed and angiosarcoma of the spleen was the final histopathological diagnosis, which was primary since no other disease site was revealed.Discussion. The incidence of the disease is 0.14–0.23 cases per million, with slight male predominance. Etiology is not established and clinical presentation may confuse even experienced physicians. Imaging modalities cannot differentiate the lesion from other vascular splenic neoplasms and the correct diagnosis is mainly set after histopathological examination of the resected spleen. As with other sarcomas, surgery is the only curative approach, while chemo- and radiotherapy have poor results. Prognosis remains dismal.

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Spontaneous splenic rupture occurring as a complication of symptomfree infections mononucleosis

Orvosi Hetilap ◽

10.1556/oh.2007.28094 ◽

2007 ◽

Vol 148 (29) ◽

pp. 1381-1384 ◽

Cited By ~ 2

Author(s):

Márta Szokó ◽

András Matolcsy ◽

Gábor Kovács ◽

Gábor Simon

Keyword(s):

Splenic Rupture ◽

Spontaneous Splenic Rupture ◽

Epstein Barr

A lépruptura a mononucleosis infectiosa ritka szövődménye, a betegek 0,1–0,5%-ánál következik be. Ez a betegség leggyakoribb halálos komplikációja. A mononucleosisra jellemző egyéb tünetek nélkül kialakuló spontán lépruptura különösen ritka, váratlan bekövetkezése miatt a fatális kimenetel lehetőségével fenyeget. A szerzők egy 16 éves, spontán lépruptura miatt splenectomizált fiú esetét ismertetik, akinél a szerológiai vizsgálatok friss Epstein–Barr-vírusinfekciót igazoltak, a mononucleosis infectiosa egyéb tünetei, jelei nélkül. Áttekintik a mononucleosisban kialakuló lépruptura diagnosztikáját és kezelését.

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An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration

European Journal of Medical Case Reports ◽

10.24911/ejmcr/173-1567102492 ◽

2020 ◽

pp. 285-287

Author(s):

Marta Martinez ◽

Cristina Maza

Keyword(s):

Splenic Rupture ◽

Granulocyte Colony Stimulating Factor ◽

Colony Stimulating Factor ◽

Spontaneous Splenic Rupture ◽

Stimulating Factor

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Faecopneumothorax due to missing diaphragmatic hernia: a case report

Journal of Medical Case Reports ◽

10.1186/s13256-020-02606-3 ◽

2021 ◽

Vol 15 (1) ◽

Author(s):

Resul Nusretoğlu ◽

Yunus Dönder

Keyword(s):

Computed Tomography ◽

Diaphragmatic Hernia ◽

Colon Resection ◽

Emergency Laparotomy ◽

Hernia Sac ◽

Case Presentation ◽

Abdominal Tenderness ◽

History Of ◽

Diaphragmatic Hernias ◽

Tomography Scan

Abstract Background Diaphragmatic hernias may occur as either congenital or acquired. The most important cause of acquired diaphragmatic hernias is trauma, and the trauma can be due to blunt or penetrating injury. Diaphragmatic hernia may rarely be seen after thoracoabdominal trauma. Case presentation A 54-year-old Turkish male patient admitted to the emergency department with abdominal pain and dyspnea ongoing for 2 days. He had general abdominal tenderness in all quadrants. He had a history of a stabbing incident in his left subcostal region 3 months ago without any pathological findings in thoracoabdominal computed tomography scan. New thoracoabdominal computed tomography showed a diaphragmatic hernia and fluid in the hernia sac. Due to respiratory distress and general abdominal tenderness, the decision to perform an emergency laparotomy was made. There was a 6 cm defect in the diaphragm. There were also necrotic fluids and stool in the hernia sac in the thorax colon resection, and an anastomosis was performed. The defect in the diaphragm was sutured. The oral regimen was started, and when it was tolerated, the regimen was gradually increased. The patient was discharged on the postoperative 11th day. Conclusions Acquired diaphragmatic hernia may be asymptomatic or may present with complications leading to sepsis. In this report, acquired diaphragmatic hernia and associated colonic perforation of a patient with a history of stab wounds was presented.

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Successful laparoscopic resection of ovarian abscess caused by Staphylococcus aureus in a 13-year-old girl: a case report and review of literature

BMC Women s Health ◽

10.1186/s12905-021-01335-z ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Tsuyoshi Murata ◽

Yuta Endo ◽

Shigenori Furukawa ◽

Atsushi Ono ◽

Yuichiroh Kiko ◽

...

Keyword(s):

Staphylococcus Aureus ◽

Adolescent Girls ◽

Laparoscopic Resection ◽

Sexually Active ◽

Fallopian Tubes ◽

Review Of Literature ◽

Case Presentation ◽

Intact Uterus ◽

Ovarian Abscess ◽

Tomography Scan

Abstract Background Ovarian abscesses, which occur mostly in sexually active women via recurrent salpingitis, occur rarely in virginal adolescent girls. Here, we present a case of an ovarian abscess in a virginal adolescent girl who was diagnosed and treated by laparoscopy. Case presentation A 13-year-old healthy girl presented with fever lasting for a month without abdominal pain. Computed tomography scan and magnetic resonance imaging indicated a right ovarian abscess. Laparoscopic surgery revealed a right ovarian abscess with intact uterus and fallopian tubes. The abscess was caused by Staphylococcus aureus. The patient recovered completely after excision of the abscess, followed by antibiotic treatment. Conclusions Ovarian abscess may occur in virginal adolescent girls; Staphylococcus aureus, an uncommon species causing ovarian abscess, may cause the infection.

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Excessive dynamic airway collapse during general anesthesia: a case report

JA Clinical Reports ◽

10.1186/s40981-020-00380-1 ◽

2020 ◽

Vol 6 (1) ◽

Cited By ~ 2

Author(s):

Shunichi Murakami ◽

Shunsuke Tsuruta ◽

Kazuyoshi Ishida ◽

Atsuo Yamashita ◽

Mishiya Matsumoto

Keyword(s):

General Anesthesia ◽

Airway Pressure ◽

Positive End Expiratory Pressure ◽

Computed Tomography Scan ◽

Case Presentation ◽

Airway Lumen ◽

Asthma Attack ◽

Airway Collapse ◽

History Of ◽

Tomography Scan

Abstract Background Excessive dynamic airway collapse (EDAC) is an uncommon cause of high airway pressure during mechanical ventilation. However, EDAC is not widely recognized by anesthesiologists, and therefore, it is often misdiagnosed as asthma. Case presentation A 70-year-old woman with a history of asthma received anesthesia with sevoflurane for a laparotomic cholecystectomy. Under general anesthesia, she developed wheezing, high inspiratory pressure, and a shark-fin waveform on capnography, which was interpreted as an asthma attack. However, treatment with a bronchodilator was ineffective. Bronchoscopy revealed the collapse of the trachea and main bronchi upon expiration. We reviewed the preoperative computed tomography scan and saw bulging of the posterior membrane into the airway lumen, leading to a diagnosis of EDAC. Conclusions Although both EDAC and bronchospasm present as similar symptoms, the treatments are different. Bronchoscopy proved useful for distinguishing between these two entities. Positive end-expiratory pressure should be applied and bronchodilators avoided in EDAC.

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