scholarly journals Renal Cell Carcinoma in a Horseshoe Kidney Treated with Laparoscopic Partial Nephrectomy

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Shinji Ohtake ◽  
Takashi Kawahara ◽  
Go Noguchi ◽  
Noboru Nakaigawa ◽  
Kimio Chiba ◽  
...  

Introduction. Horseshoe kidney is one of the most common congenital renal fusion anomalies. Due to its poor mobility and abnormal vasculature form, surgeons should pay close attention to all anatomical variations. Case Presentation. An 83-year-old woman was referred to our hospital because of left renal tumor in a horseshoe kidney incidentally found by her previous hospital. We performed laparoscopic partial nephrectomy. The pathological diagnosis was clear cell renal cell carcinoma. G2 INFα V-pT1a with a negative surgical margin. No evidence of recurrence has been noted, and the renal function is well preserved at 28 months after surgery. Conclusion. When performing laparoscopic partial nephrectomy for renal carcinoma, especially a horseshoe kidney, preoperative imaging is crucial for identifying the location of the renal vessels.

2014 ◽  
Vol 8 (11-12) ◽  
pp. 918 ◽  
Author(s):  
Tarik Benidir ◽  
Tiago Jacometo Coelho de Castilho ◽  
Guilherme Rodrigo Lobo Cherubini ◽  
Murilo De Almeida Luz

Horseshoe kidney has an incidence rate ranging from 1 in 400 to 1 in 1000, with a 2:1 ratio in men. It also has a predilection for chromosomal aneuploidies. From a pathophysiology standpoint, this anomaly occurs during the second to sixth week of gestation when the inferior portion of the metanephric blastema fuses to form an isthmus, commonly in the lower renal pole (90%). As a result of this fusion, the kidney may not bypass the inferior mesenteric artery and is impeded in its ascent. With an aberrant anatomical orientation and location, complications arise including hydronephrosis, renal calculi and a twofold risk of Wilms tumour. Despite these findings, the association of renal cell carcinoma (RCC) within a horseshoe kidney is extremely rare and fewer than 200 cases have been described. Therapeutically speaking, partial nephrectomies are the gold standard of treatment for renal tumours smaller than 4 cm in diameter, with a growing indication to accomplish this procedure by laparoscopic or robotic means. We report a case of an asymptomatic 58-year-old male with an incidental computed tomography scan finding of a 4-cm solid mass in the right moiety of a horseshoe kidney. He was treated by laparoscopic partial nephrectomy. There have only been 2 other reported cases to our knowledge on a laparoscopic partial nephrectomy in a horseshoe kidney for RCC. We believe that, in experienced hands, the laparoscopic approach may be used successfully for this clinical situation.


2021 ◽  
Vol 8 ◽  
Author(s):  
Feng Yu ◽  
Qian Xu ◽  
Xian-Gen Liu

Objective: To analyze the impact of laparoscopic partial nephrectomy (LPN) and open partial nephrectomy (OPN) on outcomes of complex clear cell renal cell carcinoma (ccRCC).Methods: A total of 132 high-complex ccRCC patients with a Radius Exophytic Nearness Anterior Location (R.E.N.A.L) score ≥7 enrolled in our hospital between January 2018 and June 2020 were matched and assigned to an LPN group (given LPN treatment) and an OPN group (given OPN treatment), with 66 cases in each group. Two weeks and 3 months after the operation, the renal indexes, inflammatory factors, basic perioperative conditions, and incidence of complications were compared.Results: Two weeks after the operation, the levels of SCr and CysC were elevated, with higher levels observed in the LPN group (all P < 0.05), and the eGFR levels were reduced, with a lower result in the LPN group. Three months after the operation, the two groups observed decreased levels of SCr and CysC, and an increased level of eGFR; moreover, the decreased SCr and CysC levels were still higher, and the increased eGFR was lower than those before the operation (P < 0.05). The levels of CRP and TNF-α in the two groups increased after the operation, with a lower outcome in the LPN group (P < 0.05). Moreover, the LPN group had less intraoperative blood loss and shorter postoperative length of hospital stay but longer blocking time compared to the OPN group (P < 0.05). Patients in the LPN group were recorded with a lower complication incidence compared with the OPN group (3.03 vs. 15.15%, P < 0.05).Conclusion: Both LPN and OPN enjoy significant efficacy in the treatment of complex ccRCC and effectively protect renal function. Moreover, LPN is a more acceptable option for complex ccRCC due to its numerous benefits in postoperative stress response, complications, recovery. which is worthy of promotion with safety and feasibility.


2018 ◽  
Vol 12 (5) ◽  
pp. E253-5 ◽  
Author(s):  
Miles Mannas ◽  
Ryan Flannigan ◽  
Michael Eng

Horseshoe kidney (HSK) is a benign malformation characterized by three anatomic abnormalities: ectopia, malrotation, and vascular changes.1 Renal cell carcinoma (RCC) comprises approximately 53.8% of HSK malignancies. The incidence of RCC within HSK is predicted to equal that within the general population, approximately 5.2/100 000 individuals.2-4 Surgical resection of these tumors has been described in the literature. Evidence is mounting that partial nephrectomy, rather than radical nephrectomy, and minimally invasive techniques for T3a RCC is safe and attains equivalent oncologic outcomes.5,6 Review of the literature reveals no case reports of laparoscopic partial nephrectomy for T3a RCC, and therefore, this is the first report of a laparoscopic partial nephrectomy of T3a RCC HSK with renal vein tumour thrombus.


2016 ◽  
Vol 2 (1) ◽  
pp. 18-20 ◽  
Author(s):  
Murat Binbay ◽  
Emrah Yuruk ◽  
Burak Ucpinar ◽  
Zerrin Binbay ◽  
Aykut Colakerol ◽  
...  

2019 ◽  
Vol 26 ◽  
pp. 100940 ◽  
Author(s):  
Kimiaki Takagi ◽  
Kota Kawase ◽  
Kenichi Minoshima ◽  
Masayoshi Yamaha ◽  
Masanobu Horie

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