scholarly journals In Vitro Comparison of Fluoride, Magnesium, and Calcium Phosphate Materials on Prevention of White Spot Lesions around Orthodontic Brackets

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Selda Lale ◽  
Hikmet Solak ◽  
Evren Hınçal ◽  
Levent Vahdettin
Keyword(s):  
Orthodontic Brackets ◽  
White Spot ◽  
Tooth Surface ◽  
White Spot Lesions ◽  
Surface Appearance ◽  
Time Points ◽  
Fluoride Toothpaste ◽  
Hygiene Practices ◽  
Fixed Appliances

One common negative side effect of orthodontic treatment with fixed appliances is the development of white spot lesions (WSLs) around brackets. This study is aimed at comparing the efficacy of various oral hygiene practices in preventing enamel demineralization around orthodontic brackets under similar in vitro conditions. The study included 90 extracted bovine incisors, which were randomized into six groups: fluoride toothpaste (FT), nonfluoride toothpaste (NFT), fluoride varnish plus fluoride toothpaste (FV+FT), CPP-ACP varnish plus fluoride toothpaste (CPP-ACP+FT), medical minerals gel plus nonfluoride toothpaste (MMG+NFT), and no intervention (control). All groups were subjected to demineralization and remineralization cycles. Visual appraisals were used to evaluate the changes in the enamel surface appearance at the beginning and end of the experiment. The changes in the demineralization degree were evaluated by measuring the Ca+2 concentration in the demineralization solution at different time points. The majority of teeth in the CPP-ACP+FT group exhibited no shift in appearance, whereas in the other groups, a slight change in enamel translucency was observed. At all the time points, the Ca+2 concentration in the demineralization solution in the CPP-ACP+FT group was the least among all other groups. At day 5, MMG+NFT’s preventive efficacy was significantly higher than FV+FT’s, but at days 10, 15, and 19, their efficacy was similar. However, at all the time points, MMG+NFT’s efficacy was significantly higher than that of control, whereas FV+FT’s efficacy was decreased at days 10, 15, and 19 and was close to the efficacy of control. To fight WSLs, early diagnosis was of great importance and examination of the tooth surface after air-drying for 5 s was recommended.

scholarly journals Effects of Fluoride and Calcium Phosphate Materials on Remineralization of Mild and Severe White Spot Lesions

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Zixiang Dai ◽  
Min Liu ◽  
Yansong Ma ◽  
Li Cao ◽  
Hockin H. K. Xu ◽  
...  
Keyword(s):  
White Spot ◽  
Tooth Surface ◽  
White Spot Lesions ◽  
Fluoride Toothpaste ◽  
Hygiene Practices ◽  
Combined Use ◽  
Diagnodent Pen ◽  
Demineralized Enamel ◽  
Mineralization Degree ◽  
Quantitative Indicators

Fixed orthodontic treatments often lead to enamel demineralization and cause white spot lesions (WSLs). The aim of this study was to evaluate the mineralization degree of 2 types of WSLs based on ICDAS index and compare the remineralizing efficacy of 3 oral hygiene practices after 1 month and 3 months. 80 mild demineralized and 80 severe demineralized enamel specimens were randomized into three treatments: fluoride toothpaste (FT), fluoride varnish plus fluoride toothpaste (FV+FT), and CPP-ACP plus fluoride toothpaste (CPP-ACP+FT). Microhardness tester, DIAGNODent Pen 2190, and scanning electron microscope were used to evaluate the changes of mineralization degree. Both qualitative and quantitative indicators suggested that the mild and severe white spot lesions were different in the degree of mineralization. Severe WSLs demineralized much more seriously than mild lesions even after 3 months of treatment. Despite the variation in severity, both lesions had the same variation trend after each measure was applied: FT had weak therapeutic effect, FV + FT and CPP-ACP + FT were effective for remineralization. Their remineralizing efficacy was similar after 1 month, and combined use of CPP-ACP plus F toothpaste was more effective after 3 months. In order to fight WSLs, early diagnosis was of great importance, and examination of the tooth surface after air-dry for 5 seconds was recommended. Also, when WSLs were found, added remineralizing treatments were required.

scholarly journals Preventive effect of fluoridated orthodontic resins subjected to high cariogenic challenges

2010 ◽  
Vol 21 (3) ◽  
pp. 211-215 ◽  
Author(s):  
Paula Passalini ◽  
Tatiana Kelly da Silva Fidalgo ◽  
Erika Machado Caldeira ◽  
Rogerio Gleiser ◽  
Matilde da Cunha Gonçalves Nojima ◽  
...  
Keyword(s):  
Color Change ◽  
Artificial Saliva ◽  
Orthodontic Brackets ◽  
White Spot ◽  
White Spot Lesion ◽  
White Spot Lesions ◽  
Preventive Effect ◽  
Ph Cycling ◽  
Inhibition Zones

The aim of the present study was to evaluate the in vitro caries preventive effect of fluoridated orthodontic resins under pH cycling with two types of acid demineralizing saliva. Brackets were bonded to 60 bovine incisors, using either Transbond Plus Color Change (n=30) or Orthodontic Fill Magic (n=30) orthodontic resins. Each group of resin was divided into 3 subgroups (n=10): immersion in remineralizing artificial saliva for 14 days, pH cycling with high cariogenic challenge in acid saliva with pH 5.5, and acid saliva with pH 4.5. After 14 days of pH cycling, the caries preventive effect on the development of white spot lesion was evaluated considering the presence of inhibition zones to white spot lesions using two scores: 0= absence and 1= presence. Kruskal Wallis and Mann-Whitney tests (a=0.05) were used. Formation of white spot lesions was observed only under pH cycling using acid saliva with pH 4.5; with Transbond Plus Color Change being significantly more effective (p<0.05) in preventing the appearance of white spot lesions effect than Orthodontic Fill Magic. The acidity of the demineralizing solution influenced the formation of white spot lesions around orthodontic brackets under highly cariogenic conditions. Transbond Plus Color Change resin presented higher caries preventive effect than Orthodontic Fill Magic.

Fluoride varnish for the prevention of white spot lesions during orthodontic treatment with fixed appliances: a randomized controlled trial

2019 ◽  
Vol 42 (3) ◽  
pp. 326-330 ◽  
Author(s):  
Mikael Sonesson ◽  
Anna Brechter ◽  
Salem Abdulraheem ◽  
Rolf Lindman ◽  
Svante Twetman
Keyword(s):  
Placebo Group ◽  
Orthodontic Treatment ◽  
Test Group ◽  
Ammonium Fluoride ◽  
Dropout Rate ◽  
White Spot ◽  
Fluoride Varnish ◽  
White Spot Lesions ◽  
Randomized Controlled ◽  
Fixed Appliances

Summary Background Self-applied and professional fluorides are key elements to limit caries-related side-effects during orthodontic treatment with fixed appliances. Objective To evaluate the effectiveness of a new fluoride varnish formula containing 1.5% ammonium fluoride in preventing white spot lesions (WSLs) in adolescents undergoing multi-bracket orthodontic treatment. Subjects and methods The study employed a randomized controlled triple-blinded design with two parallel arms. One hundred eighty-two healthy adolescents (12–18 years) referred to three orthodontic specialist clinics were eligible and consecutively enrolled. Informed consent was obtained from 166 patients and they were randomly allocated to a test or a placebo group (with aid of a computer program, generating sequence numbers in blocks of 15). In the test group, fluoride varnish was applied in a thin layer around the bracket base every sixth week during the orthodontic treatment, while patients in the placebo group received a varnish without fluoride. The intervention started at onset of the fixed appliances and continued until debonding. The endpoint was prevalence and severity of WSLs on the labial surfaces of the maxillary incisors, canines, and premolars as scored from high-resolution pre- and post-treatment digital photos with aid of a four-level score. Results One hundred forty-eight patients completed the trial, 75 in the test group and 73 in the placebo group (dropout rate 10.8%). The total prevalence of WSL’s on subject level after debonding was 41.8% in the test group and 43.8% in the placebo group. The number of patients exhibiting more severe lesions (score 3 + 4) was higher in the placebo group (P &lt; 0.05); the absolute risk reduction was 14% and the number needed to treat was 7.1. Limitations The multicentre design with somewhat diverging routines at the different clinics may have increased risk for performance bias. No health-economic evaluation was carried out. Conclusions Regular applications of an ammonium fluoride varnish reduced the prevalence of advanced WSL during treatment with fixed orthodontic appliances. Clinical trial registration ClinicalTrials.gov (NCT03725020). Protocol The protocol was not published before trial commencement.

Color masking prediction of posterior white spot lesions by resin infiltration in vitro

2020 ◽  
Vol 95 ◽  
pp. 103308
Author(s):  
Ayla Macyelle de Oliveira Correia ◽  
Alessandra Bühler Borges ◽  
Carlos Rocha Gomes Torres
Keyword(s):  
White Spot ◽  
White Spot Lesions ◽  
Resin Infiltration

scholarly journals Impact of self-assembling peptides in remineralisation of artificial early enamel lesions adjacent to orthodontic brackets

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anahita Jablonski-Momeni ◽  
R. Nothelfer ◽  
M. Morawietz ◽  
A. Kiesow ◽  
H. Korbmacher-Steiner
Keyword(s):  
Orthodontic Brackets ◽  
Fluoride Varnish ◽  
White Spot Lesions ◽  
Single Application ◽  
Group Iii ◽  
Self Assembling ◽  
Group I ◽  
Human Enamel ◽  
Fixed Appliances ◽  
Group Ii

Abstract Enamel demineralisation can occur as a side effect during orthodontic treatment with fixed appliances. This study aimed to evaluate the efficacy of the self-assembling peptide P11-4 for remineralisation combined with fluorides, compared to application of fluoride varnish alone. De- and remineralisation was assessed by Quantitative light-induced fluorescence (QLF). Orthodontic brackets were bonded on 108 human enamel samples and white spot lesions were created. The samples were allocated randomly into three groups: Group I received no treatment, group II had a single application of fluoride varnish (22,600 ppm), and group III was treated with P11-4 following a single application of fluoride varnish. Quantitative light-induced fluorescence (QLF) measurements were performed at baseline, after demineralisation and after storage in remineralisation solution for 7 and 30 days. Non-parametric tests (Kruskal–Wallis test and Friedman test) were used for further analysis. After demineralisation, all samples showed a median ΔF -9.38% ± 2.79. After 30 days median ΔF values were as followed: group I = -9.04% ± 2.51, group II = -7.89 ± 2.07, group III = -6.08% ± 2.79). The median ΔF values differed significantly between all groups at all investigation times (p < 0.00001). Application of P11-4 with fluoride varnish was superior to the use of fluorides alone for remineralisation of enamel adjacent to brackets.

Novel evaluation and treatment techniques for white spot lesions. An in vitro study

2017 ◽  
Vol 20 (3) ◽  
pp. 170-176 ◽  
Author(s):  
T. A. Bakhsh ◽  
A. S. Bakry ◽  
M. M. Mandurah ◽  
M. A. Abbassy
Keyword(s):  
In Vitro Study ◽  
Vitro Study ◽  
White Spot ◽  
White Spot Lesions ◽  
Treatment Techniques
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