Localized Chronic Form of Langerhans Cell Histiocytosis in the Femur of a 16-Year-Old Male Successfully Treated with Radiofrequency Ablation

Only three cases of patients suffering from a localized chronic form of Langerhans cell histiocytosis (LCH) successfully treated with radiofrequency ablation (RFA) have been published so far. This is the first case report of a patient with a localized chronic form of LCH of the femur, which was successfully treated with percutaneous image-guided RFA, and who was evaluated pre-RFA and followed up post-RFA for a period of 48 months, in order to validate the safety and efficacy of this method and to obtain imaging studies depicting the actual in situ changes taking place post-RFA. RFA was proved to be a safe and efficient method when treating patients with a localized chronic form of LCH.

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Langerhans cell histiocytosis of the orbit and frontal sinus of the adult woman: A first case report in Poland

Surgical Neurology International ◽

10.25259/sni_140_2019 ◽

2019 ◽

Vol 10 ◽

pp. 234

Author(s):

Kacper Kostyra ◽

Bogusław Kostkiewicz

Keyword(s):

Case Report ◽

Frontal Sinus ◽

Langerhans Cell Histiocytosis ◽

Histopathological Examination ◽

Langerhans Cell ◽

Radical Excision ◽

Multisystem Disease ◽

Upper Eyelid ◽

First Case ◽

The Right

Background: Langerhans cell histiocytosis (LCH) is a term describing a clonal proliferation of pathologic Langerhans cells (histiocytes), which may manifest as unisystem (unifocal or multifocal) or multisystem disease. LCH is a rare cause of the orbital tumor with the predilection to its lateral wall which is particularly common in children. Case Description: We report an unusual case of a 33-year-old woman, 6 months after childbirth, who presented with the edema of the right orbit and upper eyelid with headaches. On physical examination, the patient had a right superior and lateral swelling of the eyelid and the orbit and right enophthalmos, without blurred vision. Magnetic resonance imaging showed well-defined, expansile, intensely homogeneously enhancing mass lesion in the right superolateral orbital rim with the destruction of the upper wall of the orbit, growing into the frontal sinus and frontal part of the cranium with the bold of the dura mater in this region. Radical excision of the tumor was achieved through a right fronto-temporo-orbito-zygomatic craniotomy. Histopathological examination had confirmed the diagnosis of the LCH. The patient was discharged home with a modified Rankin Scale score of 0. Conclusion: The main purpose of this case report is that LCH should be considered as one of the possible causes of quickly appearing tumor of the orbit in adults.

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The Rapid Evolution of CT Findings in Pulmonary Langerhans Cell Histiocytosis: A Case Report

Journal of the Korean Radiological Society ◽

10.3348/jkrs.2007.57.1.27 ◽

2007 ◽

Vol 57 (1) ◽

pp. 27

Author(s):

Tae Wook Kang ◽

Kyung Soo Lee ◽

Eun Yoon Cho

Keyword(s):

Case Report ◽

Langerhans Cell Histiocytosis ◽

Rapid Evolution ◽

Langerhans Cell ◽

Pulmonary Langerhans Cell Histiocytosis ◽

Ct Findings

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Successful outcome of Langerhans cell histiocytosis complicated by therapy-related myelodysplasia and acute myeloid leukemia: a case report

Cases Journal ◽

10.1186/1757-1626-1-101 ◽

2008 ◽

Vol 1 (1) ◽

Cited By ~ 2

Author(s):

Khalid A Al-Anazi ◽

Abdulrahman Alshehri ◽

Hazza A Al-Zahrani ◽

Fahad I Al-Mohareb ◽

Irfan Maghfoor ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Case Report ◽

Myeloid Leukemia ◽

Langerhans Cell Histiocytosis ◽

Langerhans Cell ◽

Successful Outcome ◽

Acute Myeloid

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Langerhans Cell Histiocytosis: Case Report With Cytogenetic Approach

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2013.10.047 ◽

2014 ◽

Vol 117 (2) ◽

pp. e126

Author(s):

JÉSSICA ANNE PEREIRA CORRÊA ◽

LIONEY NOBRE CABRAL ◽

TIAGO NOVAES PINHEIRO ◽

ELIANA BRASIL ALVES ◽

ANGELA MARIA FERNANDES DOS SANTOS

Keyword(s):

Case Report ◽

Langerhans Cell Histiocytosis ◽

Langerhans Cell

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Unifocal Granuloma of Femur due to Langerhans' Cell Histiocytosis: A Case Report and Review of the Literature

Case Reports in Medicine ◽

10.1155/2010/686031 ◽

2010 ◽

Vol 2010 ◽

pp. 1-3 ◽

Cited By ~ 2

Author(s):

Harpreet Singh ◽

Satnam Kaur ◽

P. Yuvarajan ◽

Nishant Jain ◽

Lalit Maini

Keyword(s):

Case Report ◽

Clinical Data ◽

Case History ◽

Langerhans Cell Histiocytosis ◽

Eosinophilic Granuloma ◽

Pediatric Population ◽

Langerhans Cell ◽

Long Bones ◽

Review Of The Literature ◽

Osteolytic Lesions

The radiological diagnosis of osteolytic lesions of the long bones in pediatric population constitutes a challenge when the case history and clinical data are uncharacteristic. We believe that the description of few clinically and histologically proven cases to verify the existence of radiological signs useful for diagnosis may be of interest. Here, we describe a case of Langerhans' cell histiocytosis (LCH) presenting as unifocal eosinophilic granuloma of femur along with a brief review of the literature.

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