Thoracic Complications in Behçet’s Disease: Imaging Findings

Behçet’s disease (BD) causes vascular inflammation and necrosis in a wide range of organs and tissues. In the thorax, it may cause vascular complications, affecting the aorta, brachiocephalic arteries, bronchial arteries, pulmonary arteries, pulmonary veins, capillaries, and mediastinal and thoracic inlet veins. In BD, chest radiograph is commonly used for the initial assessment of pulmonary symptoms and complications and for follow-up and establishment of the response to treatment. With the advancement of helical or multislice computed tomography (CT) technologies, such noninvasive imaging techniques have been employed for the diagnosis of vascular lesions, vascular complications, and pulmonary parenchymal manifestations of BD. CT scan (especially, CT angiography) has been used to determine the presence and severity of pulmonary complications without resorting to more invasive procedures, in conjunction with gadolinium-enhanced three-dimensional (3D) gradient-echo magnetic resonance (MR) imaging with the subtraction of arterial phase images. These radiologic methods have characteristics that are complementary to each other in diagnosis of the thoracic complications in BD. 3D ultrashort echo time (UTE) MR imaging (MRI) could potentially yield superior image quality for pulmonary vessels and lung parenchyma when compared with breath-hold 3D MR angiography.

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Clinical Characteristics of Behcet’s Disease in 453 Egyptian Patients Suffering from Uveitis with Gender Comparison

Current Rheumatology Reviews ◽

10.2174/1573397115666191007102317 ◽

2020 ◽

Vol 16 (4) ◽

pp. 285-292 ◽

Cited By ~ 2

Author(s):

Mohsen Elshahaly ◽

Iman Abd El Latif ◽

Hassan Bassiouni

Keyword(s):

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Sinus Thrombosis ◽

Vascular Complications ◽

Joint Involvement ◽

Acute Phase Reactants ◽

Behcet's Disease ◽

Sagittal Sinus ◽

Markers Of Inflammation

Objective: To describe the clinical features in patients with Behcet’s disease suffering from uveitis in Egypt and to compare the findings between both genders. Methods: 453 subjects fulfilling the 1990 Classification criteria for Behcet’s disease and with uveitis in at least one eye. Follow-up was done for two years. Results: Oral ulcers and recurrent iridocyclitis occurred in all patients during their disease course. The prevalence of genital ulcers, erythema nodosum, and joint involvement were similar between both sexes. The prevalence of all ocular findings was higher in females except for retinal hemorrhages. The incidence of secondary cataract and glaucoma in addition to vitreous opacities was similar between both sexes. 13.7% of patients had GIT manifestations. Vascular complications were present in 128 (28.2%) patients. : Aseptic meningitis and hemiplegia were only found in males. 1.7% of males and 3.2% of females suffered from brainstem involvement. Superior sagittal sinus thrombosis was present in females only. Acute phase reactants (ESR & CRP) were significantly higher in females (p<0.0001). Conclusion: The disease characteristics of BD patients with uveitis in Egypt might be different from the BD patients of other countries. The markers of inflammation were higher in females compared to males. The ocular manifestations were more common in females.

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Neuro-Behcet's Disease: Diagnostic Usefulness of MR Imaging

Journal of the Korean Radiological Society ◽

10.3348/jkrs.2000.43.2.145 ◽

2000 ◽

Vol 43 (2) ◽

pp. 145

Author(s):

Song Soo Kim ◽

Chang June Song ◽

Ae Young Lee ◽

Chung Ho Pak

Keyword(s):

Mr Imaging ◽

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Behcet's Disease ◽

Diagnostic Usefulness

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Decreasing incidence and severity of Behçet’s disease: a changing trend in epidemiological spectrum possibly associated with oral health

TURKISH JOURNAL OF MEDICAL SCIENCES ◽

10.3906/sag-2003-147 ◽

2020 ◽

Vol 50 (7) ◽

pp. 1587-1590

Author(s):

Gonca MUMCU ◽

Fatma ALİBAZ ÖNER ◽

Tülin ERGUN ◽

Haner DİRESKENELİ

Keyword(s):

Oral Health ◽

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Epidemiological Studies ◽

Inflammatory Disorder ◽

Behcet's Disease ◽

Disease Spectrum ◽

Wide Range ◽

Ancient Silk Road

Behçet’s disease (BD) is a systemic and inflammatory disorder that is mainly present along the ancient Silk Road, from the Mediterranean Sea to East Asia. A wide range of prevalence figures (0.1–420/100,000) have been reported for BD, also among Turkish populations of similar genetic background living in different countries. Recently, a decline in the incidence of BD and a change of the disease spectrum to less-severe manifestations have been reported from Japan and Korea, two genetically homogenous, affluent populations with limited immigration. It was hypothesized that a decline in infectious diseases, especially dental/periodontal infections, associated with the improvement in oral health, could be a part of these changes in the disease expression. Further epidemiological studies in other populations might demonstrate whether there is a worldwide similar trend and may provide a better understanding of the triggering factors for the onset and course of BD.

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Die chirurgische Behandlung des M. Behçet

VASA ◽

10.1024/0301-1526.32.3.149 ◽

2003 ◽

Vol 32 (3) ◽

pp. 149-153 ◽

Cited By ~ 35

Author(s):

Ceyran ◽

Akçali ◽

Kahraman

Keyword(s):

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Vascular Complications ◽

Artery Aneurysm ◽

Graft Occlusion ◽

Iliac Artery Aneurysm ◽

Behcet's Disease ◽

Multiple Aneurysms ◽

Risk Of Rupture

Background: Vascular complications can be seen in patients with Behçet’s disease. Arterial and venous complications may be found separately or concomitantly in patients. Patients and methods: Out of 29 patients with vasculo-Behçet’s disease 7 patients with multiple aneurysms and venous lesions were documented over a period of 20 years. All patients were male, ranging in age from 24 to 52 years. The mean duration of the disease was 6 ± 2 years. The aneurysms were found in the following locations: one pulmonary artery, two abdominal aorta, four iliac, five femoral, and two popliteal artery. Both aneurysmal and occlusive lesions were present in three patients. In the venous lesions associated with the aneurysms there were three deep and three superficial venous thrombosis. Two patients had caval involvement-superior and inferior vena caval syndromes. Results: We performed seven interposition grafting by polytetrafloroethylene, one Y-grafting, one aneurysmorrhaphy, one lobectomy. Re-anastomosis was performed in two patients who had anastomotic aneurysms and graft occlusion without disabling ischemia. Venous pathologies were treated by medical therapy. The patients were followed up between 1 to 8 years. One of the patients with iliac artery aneurysm died due to gastrointestinal bleeding 15 months after the operation. Conclusions: In conclusion, when an aneurysm has been found in a patient with Behçet’s disease, the patient should be scanned for possible multiple aneurysms and venous lesions since they might be found together. Surgical treatment, when feasible, should be performed in cases with Behçet aneurysms because of a high risk of rupture. However, the possibility of an anastomotic aneurysm developing after surgery should also be kept in mind.

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Neuro-Behcet's Disease: Initial and Follow-up MR Imaging Findings

Journal of the Korean Radiological Society ◽

10.3348/jkrs.1998.39.3.469 ◽

1998 ◽

Vol 39 (3) ◽

pp. 469

Author(s):

Chan Sung Kim ◽

Sun Seob Choi ◽

Ha Jong Lee ◽

Dong Ho Ha ◽

Yong Il Lee

Keyword(s):

Mr Imaging ◽

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Imaging Findings ◽

Behcet's Disease

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Massive lower gastrointestinal bleeding associated with solitary rectal ulcer in a patient with Behçet’s disease

Reumatismo ◽

10.4081/reumatismo.2015.819 ◽

2015 ◽

Vol 67 (2) ◽

Cited By ~ 1

Author(s):

C. Bes ◽

Ü. Dağlı ◽

F. Yılmaz ◽

M. Soy

Keyword(s):

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Rectal Ulcer ◽

Solitary Rectal Ulcer ◽

Solitary Rectal Ulcer Syndrome ◽

Behcet's Disease ◽

Diffi Cult ◽

Wide Range ◽

Endoscopic Picture

Solitary rectal ulcer syndrome is a rare benign disorder that has a wide range of clinical presentations and variable endoscopic fi ndings which makes it diffi cult to diagnose and treat. The clinical and endoscopic picture in this condition can also mimic malign ulceration, malignancy or Crohn’s disease. Behçet’s disease can affect the gastrointestinal tract. However to the best of our knowledge, no case with solitary rectal ulceration has been reported so far in literature. We herein present a patient diagnosed with Behçet’s disease admitted to our clinic with rectal bleeding due to solitary rectal ulceration.

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Intestinal Behçet's disease: breath-hold MR imaging

Abdominal Imaging ◽

10.1007/s002610000161 ◽

2001 ◽

Vol 26 (3) ◽

pp. 309-314 ◽

Cited By ~ 4

Author(s):

J. K. You ◽

M.-J. Kim ◽

S. Park ◽

J.-J. Chung ◽

W. H. Kim

Keyword(s):

Mr Imaging ◽

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Breath Hold ◽

Intestinal Behçet’S Disease ◽

Behcet's Disease ◽

Intestinal Behcet’S Disease ◽

Intestinal Behçet's Disease

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Anticardiolipin Antibodies and Retinal Vascular Complications in Behçet's Disease

Ophthalmic Surgery Lasers and Imaging Retina ◽

10.3928/1542-8877-19970801-07 ◽

1997 ◽

Vol 28 (8) ◽

pp. 653-656

Author(s):

Yildiz Özdemir ◽

Feyza Önder ◽

Alper Yarangümeli ◽

Cumhur Küçükkuyumcu ◽

Gülcan Kural

Keyword(s):

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Vascular Complications ◽

Anticardiolipin Antibodies ◽

Behcet's Disease

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Budd-Chiari syndrome in association with Behçet's disease: review of the literature

Sao Paulo Medical Journal ◽

10.1590/s1516-31802011000200009 ◽

2011 ◽

Vol 129 (2) ◽

pp. 107-109 ◽

Cited By ~ 4

Author(s):

Daniela Carvalho ◽

Fernando Oikawa ◽

Nilce Mitiko Matsuda ◽

Alice Tatsuko Yamada

Keyword(s):

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Vascular Complications ◽

Young Male ◽

Review Of The Literature ◽

Budd Chiari Syndrome ◽

Behcet's Disease ◽

Chiari Syndrome ◽

Thrombotic Complications

The risk that patients with Behçet's disease may develop various thrombotic complications has been previously described. Although vascular complications from Budd-Chiari syndrome associated with Behçet's disease have been described, the pathogenic mechanisms are still unknown. Severe vascular complications present in Budd-Chiari syndrome associated with Behçet's disease are very common among young male adults. The objective of this study was to review the literature and present the association of Budd-Chiari syndrome with Behçet's disease.

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