scholarly journals Old Era Continues in Modern World: A Case Report of Scurvy Induced Myopathy in Patient with Chronic Alcoholism

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Girish Singhania ◽  
Namrata Singhania ◽  
Neha Chawla

We report a case of myopathy in a chronic alcoholic patient with scurvy who presented with generalized weakness, myalgias, and arthralgia. Our case raises awareness regarding rare interaction between vitamin C deficiency and myopathy which is seen more commonly in patients with history of chronic alcoholism and low socioeconomic status. Early treatment with vitamin C replacement is helpful in treatment of the disease and its complications.

Author(s):  
Jane Buckingham

Historical analyses, as well as more contemporary examples of disability and work, show that the experience of disability is always culturally and historically mediated, but that class—in the sense of economic status—plays a major role in the way impairment is experienced as disabling. Although there is little published on disability history in India, the history of the Indian experience of caste disability demonstrates the centrality of work in the social and economic expression of stigma and marginalization. An Indian perspective supports the challenge to the dominant Western view that modern concepts of disability have their origins in the Industrial Revolution. Linkage between disability, incapacity to work, and low socioeconomic status are evident in India, which did not undergo the workplace changes associated with industrialization in the West.


Dental Update ◽  
2019 ◽  
Vol 46 (7) ◽  
pp. 662-671
Author(s):  
Rachael Y Jablonski ◽  
Bethany Rushworth ◽  
Kathryn A Durey

Gingival overgrowth is the enlargement of gingival tissues and has various underlying aetiological factors. This case report highlights the multifactorial aetiology of gingival overgrowth for a patient who was prescribed an immunosuppressive strategy following renal transplantation, had poor levels of oral hygiene and a diet deficient in fruit and vegetables. The report highlights the importance of a detailed assessment to identify all underlying factors and demonstrates how a referral to the specialist services for gingival overgrowth led to a diagnosis of vitamin C deficiency. It also illustrates how both patient engagement and a conservative cause-related therapy can achieve a satisfactory resolution without any surgical intervention. CPD/Clinical Relevance: This case report highlights the importance of a detailed assessment to diagnose all relevant underlying aetiological factors involved in the development of gingival overgrowth. It also illustrates how both patient engagement and a conservative cause-related therapy can achieve a satisfactory resolution of gingival overgrowth without any surgical intervention.


2021 ◽  
Vol 24 (9) ◽  
pp. 273-276
Author(s):  
Anna Attico ◽  
Alessandra Iacono ◽  
Loretta Biserna ◽  
Sara Brandolini ◽  
Federico Marchetti

The paper presents the case of a 16-year-old girl with a 6-month history of eating disorder, restrictive subtype and diffuse ecchymosis. Anamnestic history and laboratory investigations allowed excluding coagulation disorders and making the diagnosis of vitamin C deficiency. Vitamin C deficiency is a rare disease but still sporadically described in children with unusual eating habits.


2021 ◽  
Vol 2 (1) ◽  
pp. 78-83
Author(s):  
Eka Sri Rahayu ◽  
Mardy Pangarungan

A B S T R A C TScurvy is a rare case found in many countries, but it is often found in refugeeareas, especially in Africa. Vitamin C deficiency varies based on season and occursmore in men with age. The purpose of this research is to avoid misdiagnosis so thatit can be a reference in the field of medicine to diagnose and provide management onscurvy. This prospective research was conducted with one sample of research.Observation had been carried out for two months, starting at one month after thepatient was suspected with the diagnosis of scurvy. Computer Tomography (CT) Scanlumbosacral to pelvic results were normal. Laboratory test of HB result was 9.5 g/dl,in which MCV was 63.2 fL, MCH was 20.3 pg, and MCHC was 32.1 g/dl. Scurvytreatment in the first visit was 3x1 tablets vitamin C, 3x5 ml ibuprofen Syr, andphysiotherapy. The results were that the patient still suffered swollen and bleedinggums, but the pain no longer existed, pale, behavioural disorders, unable to walk,and pain in both knees. After the second visit, the child got therapy of 4x50 mg vitaminC, 1x1 tablets vitamin B12, 1x150 IU vitamin E, 1x1 tablets cavit D3, andphysiotherapy. After two weeks of treatment, there were no complaints of swelling,painful or bleeding gums. The child could straighten her legs, but she was still unableto walk due to the trauma of feeling great pain while walking. Special attention isrequired to diagnose appropriately so the doctor can minimize and preventcomplications.


mBio ◽  
2015 ◽  
Vol 6 (4) ◽  
Author(s):  
S. J. Anthony ◽  
J. A. St. Leger ◽  
E. Liang ◽  
A. L. Hicks ◽  
M. D. Sanchez-Leon ◽  
...  

ABSTRACTDescribing the viral diversity of wildlife can provide interesting and useful insights into the natural history of established human pathogens. In this study, we describe a previously unknown picornavirus in harbor seals (tentatively named phopivirus) that is related to human hepatitis A virus (HAV). We show that phopivirus shares several genetic and phenotypic characteristics with HAV, including phylogenetic relatedness across the genome, a specific and seemingly quiescent tropism for hepatocytes, structural conservation in a key functional region of the type III internal ribosomal entry site (IRES), and a codon usage bias consistent with that of HAV.IMPORTANCEHepatitis A virus (HAV) is an important viral hepatitis in humans because of the substantial number of cases each year in regions with low socioeconomic status. The origin of HAV is unknown, and no nonprimate HAV-like viruses have been described. Here, we describe the discovery of an HAV-like virus in seals. This finding suggests that the diversity and evolutionary history of these viruses might be far greater than previously thought and may provide insight into the origin and pathogenicity of HAV.


Author(s):  
Yasser Ali ◽  
Mazen Ismail ◽  
Maher Shareif ◽  
Mohanmmad Hosam El-Din ◽  
Inass Taha

Background: Acute methanol poisoning is a fatal illness. Several Atypical presentations could make it difficult to suspect the diagnosis. Case Report: A 50 years old male known chronic alcoholic presented to the emergency department with severe acute abdominal pain nausea and vomiting. He rapidly deteriorated within 2 hours to develop confusion and seizures, was found to have double gap severe metabolic acidosis and elevated serum methanol. The patient was managed with Continuous Renal Replacement Therapy (CRRT) and supportive measures. He gradually improved and was discharged with no neurological or visual complications. Conclusion and Recommendations: Acute methanol toxicity should be expected if the alcoholic patient develops a rapid neurological deterioration and shows double anion gap acidosis. Health authorities should provide the serum formic acid test for diagnosis and the fomepizole as a preferable antidote. Until then, supportive treatment, intravenous ethanol and CRRT should be immediately started in these patients.


Sign in / Sign up

Export Citation Format

Share Document