scholarly journals The Pathogenesis and Treatment of Complications in Nanophthalmos

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Ning Yang ◽  
Siyan Jin ◽  
Linlin Ma ◽  
Jia Liu ◽  
Chenli Shan ◽  
...  
Keyword(s):  
Developmental Disorder ◽  
Treatment Plan ◽  
Complex Structure ◽  
Clinical Treatment ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Clinical Phenotypes ◽  
Uveal Effusion Syndrome ◽  
High Hyperopia ◽  
Uveal Effusion

Microphthalmos is a type of developmental disorder ophthalmopathy, which can occur isolated or combined with other ocular malformations and can occur secondary to a systemic syndrome. Nanophthalmos is one of the clinical phenotypes of microphthalmos. Due to the special and complex structure of nanophthalmic eyes, the disorder is often associated with many complications, including high hyperopia, angle-closure glaucoma, and uveal effusion syndrome. The management of these complications is challenging, and conventional therapeutic methods are often ineffective in treating them. The purpose of this paper was to review the concept of nanophthalmos and present the latest progress in the study of the pathogenesis and treatment of its complications. As it is considerably challenging for ophthalmologists to prevent or treat these nanophthalmos complications, timely diagnosis and a suitable clinical treatment plan are vital to ensure that nanophthalmos patients are treated and managed effectively.

scholarly journals Transscleral cyclophotocoagulation as primary management in a nanophthalmic eye with anterior uveitis and secondary mixed mechanism glaucoma

2019 ◽  
Vol 12 (12) ◽  
pp. e232281
Author(s):  
Albert John Bromeo ◽  
Kathrin Bartilad
Keyword(s):  
Anterior Uveitis ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Eye Pain ◽  
Ocular Ultrasound ◽  
Transscleral Cyclophotocoagulation ◽  
Eye Examination ◽  
Primary Management ◽  
Uveal Effusion ◽  
Mixed Mechanism

A 36-year-old woman presented with eye pain and blurring of vision in her right eye. On eye examination, it was noted that there were angle-closure glaucoma and anterior uveitis in both eyes. Ocular ultrasound showed short axial lengths as well as a choroidal thickening in both eyes, confirming the diagnosis of nanophthalmos. Nanophthalmos is a condition where the eye is abnormally short, resulting in axial hyperopia and predisposing it to angle-closure glaucoma. The patient was initially managed medically, but the glaucoma was intractable. The patient underwent repeated sessions of transscleral cyclophotocoagulation which eventually lowered the intraocular pressure. The management of nanophthalmic eyes can be quite challenging due to the risk of inciting uveal effusion syndrome with any form of intraocular surgery. Controlled and repeated sessions of transscleral cyclophotocoagulation may be considered as a viable management option in these cases.

Uveal effusion in primary angle-closure glaucoma

Ophthalmology ◽  
2005 ◽  
Vol 112 (3) ◽  
pp. 413-419 ◽  
Author(s):  
Hiroshi Sakai ◽  
Sayo Morine-Shinjyo ◽  
Manabu Shinzato ◽  
Yoshimi Nakamura ◽  
Miyako Sakai ◽  
...  
Keyword(s):  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Uveal Effusion

scholarly journals Spectrum of Angle Closure, Uveal Effusion Syndrome, and Nanophthalmos

2016 ◽  
Vol 10 (3) ◽  
pp. 113-117 ◽  
Author(s):  
Eric Areiter ◽  
Matthew Neale ◽  
Sandra M Johnson
Keyword(s):  
Angle Closure ◽  
Uveal Effusion Syndrome ◽  
Uveal Effusion

scholarly journals Idiopathic uveal effusion syndrome causing unilateral acute angle closure in a pseudophakic patient

Eye ◽  
2011 ◽  
Vol 25 (9) ◽  
pp. 1236-1238 ◽  
Author(s):  
M Bhogal ◽  
D Mitry ◽  
M Restori ◽  
I Subak-Sharpe
Keyword(s):  
Acute Angle ◽  
Angle Closure ◽  
Uveal Effusion Syndrome ◽  
Acute Angle Closure ◽  
Uveal Effusion

scholarly journals Prevalence of Complications in Eyes With Nanophthalmos or Microphthalmos: A Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Naseer Ally ◽  
Sarah Ismail ◽  
Hassan Dawood Alli
Keyword(s):  
Systematic Review ◽  
Normal Population ◽  
Meta Analysis ◽  
Angle Closure ◽  
Exclusion Criteria ◽  
Preventative Measures ◽  
Online Databases ◽  
Uncommon Condition ◽  
High Hyperopia ◽  
Uveal Effusion

Abstract IntroductionMicrophthalmos and nanophthalmos are uncommon ocular conditions, whereby affected eyes have smaller dimensions compared to the normal population. Microphthalmos and nanophthalmos present several challenges to ophthalmologists; They have spontaneous and post-operative sequelae such as high hyperopia, angle-closure glaucoma, uveal effusion syndrome, and retinal detachment.This systematic review and meta-analysis intends to assess the prevalence of both the spontaneous complications associated with nanophthalmos and microphthalmos, as well as the post-surgical complications associated with nanophthalmos or microphthalmos. Methods and analysisArticles will be searched for, on four online databases: PubMed, EMBASE, Scopus and Web of Science. Two independent reviewers will identify the studies according to prespecified inclusion and exclusion criteria. Relevant data will be extracted and assessed for the risk of bias in each article. The data will then be pooled to determine the prevalence of complications among patients with microphthalmos and nanophthalmos. If any preventative measures are associated with lower risks of developing complications, these will be expressed as odds ratios.DiscussionAlthough nanophthalmos is an uncommon condition that affects the eye, its management and complications can be sight-threatening. Thus, it is important to counsel parents and patients correctly upon diagnosis and prior to any surgical intervention. This can only be done if the overall prevalence of complications is known.RegistrationThis systematic review has been submitted to PROSPERO for registration.

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