scholarly journals The Occurrence of Richter’s Syndrome during Treatment with Obinutuzumab and Chlorambucil

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Teng Fong Ng ◽  
Benedict Carnley ◽  
Celia Green ◽  
Dominic Spagnolo ◽  
Michael F. Leahy

Chronic lymphocytic leukaemia is a slow-growing leukaemia of developing B-lymphocytes, which may transform to an aggressive lymphoma known as Richter’s syndrome. While Richter’s syndrome can present in untreated or relapsed-refractory cases, it may occur upon the commencement of less intensity treatment regimens. We present a case of Richter’s syndrome following treatment with chlorambucil and obinutuzumab and review of available literature on the topic.

Nature ◽  
1980 ◽  
Vol 283 (5742) ◽  
pp. 76-78 ◽  
Author(s):  
John N. Hurley ◽  
Shu Man Fu ◽  
Henry G. Kunkel ◽  
R. S. K. Chaganti ◽  
James German

2004 ◽  
Vol 40 (3) ◽  
pp. 383-389 ◽  
Author(s):  
T. Robak ◽  
J.Z. Blonski ◽  
J. Gora-Tybor ◽  
M. Kasznicki ◽  
L. Konopka ◽  
...  

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