Rottlerin inhibits P2X 7 receptor‐stimulated phospholipase D activity in chronic lymphocytic leukaemia B‐lymphocytes

2006 ◽  
Vol 85 (1) ◽  
pp. 68-72 ◽  
Author(s):  
Anne N Shemon ◽  
Ronald Sluyter ◽  
James S Wiley
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
B Lymphocytes ◽  
Phospholipase D ◽  
Lymphocytic Leukaemia

Chromosome abnormalities of leukaemic B lymphocytes in chronic lymphocytic leukaemia

Nature ◽  
1980 ◽  
Vol 283 (5742) ◽  
pp. 76-78 ◽  
Author(s):  
John N. Hurley ◽  
Shu Man Fu ◽  
Henry G. Kunkel ◽  
R. S. K. Chaganti ◽  
James German
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
B Lymphocytes ◽  
Lymphocytic Leukaemia ◽  
Chromosome Abnormalities

scholarly journals The Occurrence of Richter’s Syndrome during Treatment with Obinutuzumab and Chlorambucil

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Teng Fong Ng ◽  
Benedict Carnley ◽  
Celia Green ◽  
Dominic Spagnolo ◽  
Michael F. Leahy
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
B Lymphocytes ◽  
Lymphocytic Leukaemia ◽  
Aggressive Lymphoma ◽  
Treatment Regimens ◽  
Slow Growing ◽  
Richter’S Syndrome

Chronic lymphocytic leukaemia is a slow-growing leukaemia of developing B-lymphocytes, which may transform to an aggressive lymphoma known as Richter’s syndrome. While Richter’s syndrome can present in untreated or relapsed-refractory cases, it may occur upon the commencement of less intensity treatment regimens. We present a case of Richter’s syndrome following treatment with chlorambucil and obinutuzumab and review of available literature on the topic.

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