Determination of the Role of Target Tissue Metabolism in Lung Carcinogenesis Using Conditional Cytochrome P450 Reductase-Null Mice

Lung Carcinogenesis ◽

Tissue Metabolism ◽

P450 Reductase

Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)67801-4 ◽

1991 ◽

Vol 266 (6) ◽

pp. 3372-3375

Author(s):

T Shimizu ◽

T Tateishi ◽

M Hatano ◽

Y Fujii-Kuriyama

Keyword(s):

Cytochrome P450 ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Catalytic Function ◽

Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase. Implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32834fcf4f ◽

2012 ◽

Vol 23 (4) ◽

pp. 393-405 ◽

Cited By ~ 5

Author(s):

Dorota Kostrzewa-Nowak ◽

Bohdan Bieg ◽

Mark J.I. Paine ◽

C. Roland Wolf ◽

Jolanta Tarasiuk

Keyword(s):

Cytochrome P450 ◽

Multidrug Resistant ◽

Structural Factors ◽

Hl60 Cells ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anthraquinone Derivatives ◽

Role of the prosthetic groups of NADPH-cytochrome P450 reductase in 3-hydroxyanthranilamide-catalyzed, NADPH-dependent superoxide anion production

Redox Report ◽

10.1080/13510002.1996.11747070 ◽

1996 ◽

Vol 2 (5) ◽

pp. 339-344

Author(s):

Y. Ohta ◽

R. Shinohara ◽

I. Ishiguro

Keyword(s):

Cytochrome P450 ◽

Superoxide Anion ◽

Superoxide Anion Production ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anion Production ◽

Nadph Cytochrome P450 Reductase ◽

Prosthetic Groups

New insights into the role of cytochrome P450 reductase (POR) in microsomal redox biology

Acta Pharmaceutica Sinica B ◽

10.1016/j.apsb.2012.02.002 ◽

2012 ◽

Vol 2 (2) ◽

pp. 102-106 ◽

Cited By ~ 11

Author(s):

Todd D. Porter

Keyword(s):

Cytochrome P450 ◽

Redox Biology ◽

P450 Reductase

Conformational Dynamics and the Energetics of Protein−Ligand Interactions: Role of Interdomain Loop in Human Cytochrome P450 Reductase†

Biochemistry ◽

10.1021/bi700596s ◽

2007 ◽

Vol 46 (28) ◽

pp. 8244-8255 ◽

Cited By ~ 23

Author(s):

Alex Grunau ◽

Kalotina Geraki ◽

J. Günter Grossmann ◽

Aldo Gutierrez

Keyword(s):

Cytochrome P450 ◽

Conformational Dynamics ◽

P450 Reductase ◽

Protein Ligand Interactions ◽

Human Cytochrome ◽

Ligand Interactions

1P-115 Determination of structure of heme oxygenase-1 and cytochrome P450 reductase complex by electron cryo-microscopy(The 46th Annual Meeting of the Biophysical Society of Japan)

Seibutsu Butsuri ◽

10.2142/biophys.48.s39_2 ◽

2008 ◽

Vol 48 (supplement) ◽

pp. S39

Author(s):

Ryota Nakao ◽

Yuka Tutumi ◽

Yuichiro Higashimoto ◽

Masato Noguchi ◽

Hiroshi Sakamoto ◽

...

Keyword(s):

Cytochrome P450 ◽

Annual Meeting ◽

Heme Oxygenase ◽

Heme Oxygenase 1 ◽

P450 Reductase ◽

Biophysical Society

Determination of the Rate of Reduction of Oxyferrous Cytochrome P450 2B4 by 5-Deazariboflavin Adenine Dinucleotide T491V Cytochrome P450 Reductase†

Biochemistry ◽

10.1021/bi034968u ◽

2003 ◽

Vol 42 (40) ◽

pp. 11594-11603 ◽

Cited By ~ 29

Author(s):

Haoming Zhang ◽

Larry Gruenke ◽

Dave Arscott ◽

Anna Shen ◽

Charles Kasper ◽

...

Keyword(s):

Cytochrome P450 ◽

P450 Reductase ◽

Cytochrome P450 2B4

Determination of the Redox Properties of Human NADPH-Cytochrome P450 Reductase†

Biochemistry ◽

10.1021/bi001718u ◽

2001 ◽

Vol 40 (7) ◽

pp. 1956-1963 ◽

Cited By ~ 106

Author(s):

Andrew W. Munro ◽

Michael A. Noble ◽

Laura Robledo ◽

Simon N. Daff ◽

Stephen K. Chapman

Keyword(s):

Cytochrome P450 ◽

Redox Properties ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Effector role of cytochrome P450 reductase for androstenedione binding to human aromatase

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2020.07.163 ◽

2020 ◽

Vol 164 ◽

pp. 510-517 ◽

Cited By ~ 2

Author(s):

Chao Zhang ◽

Gianluca Catucci ◽

Giovanna Di Nardo ◽

Gianfranco Gilardi

Keyword(s):

Cytochrome P450 ◽

P450 Reductase ◽

Human Aromatase

Role of LYS271 and LYS279 Residues in the Interaction of Cytochrome P4501A1 with NADPH–Cytochrome P450 Reductase

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.2000.2174 ◽

2001 ◽

Vol 385 (2) ◽

pp. 290-300 ◽

Cited By ~ 9

Author(s):

Tomas Cvrk ◽

Henry W. Strobel

Keyword(s):

Cytochrome P450 ◽

Cytochrome P4501a1 ◽

Nadph Cytochrome ◽

P450 Reductase ◽