Phase I-II study of the histone deacetylase inhibitor (HDACi) vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer (MBC): New York Cancer Consortium trial P7703.

Phase I ◽

Histone Deacetylase ◽

Metastatic Breast ◽

Phase I Study and Pilot Efficacy Analysis of Entinostat, a Novel Histone Deacetylase Inhibitor, in Chinese Postmenopausal Women with Hormone Receptor-Positive Metastatic Breast Cancer

Targeted Oncology ◽

10.1007/s11523-021-00823-4 ◽

2021 ◽

Author(s):

Jiani Wang ◽

Qingyuan Zhang ◽

Qiao Li ◽

Yuxin Mu ◽

Jing Jing ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Phase I Study ◽

Metastatic Breast ◽

Efficacy Analysis ◽

Hormone Receptor Positive ◽

Deacetylase Inhibitor ◽

Chinese Postmenopausal Women

A double-blind, randomized, placebo-controlled phase II study of the steroidal aromatase inhibitor exemestane with and without the isoform selective histone deacetylase inhibitor (HDACi) entinostat in metastatic breast cancer (MBC).

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.tps128 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. TPS128-TPS128

Author(s):

D. A. Yardley ◽

R. Ismail-Khan ◽

J. F. Eakle ◽

K. Miller ◽

D. Paul ◽

...

Keyword(s):

Breast Cancer ◽

Aromatase Inhibitor ◽

Histone Deacetylase ◽

Phase Ii ◽

Phase Ii Study ◽

Metastatic Breast ◽

Double Blind ◽

A phase I-II study of the histone deacetylase inhibitor vorinostat plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in locally advanced breast cancer

Breast Cancer Research and Treatment ◽

10.1007/s10549-014-3008-5 ◽

2014 ◽

Vol 146 (1) ◽

pp. 145-152 ◽

Cited By ~ 25

Author(s):

Yifan Tu ◽

Dawn L. Hershman ◽

Kapil Bhalla ◽

Warren Fiskus ◽

Christine M. Pellegrino ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Advanced Breast Cancer ◽

Histone Deacetylase ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Advanced Breast ◽

Weekly Paclitaxel ◽

Faculty of 1000 evaluation for A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718050520.793482822 ◽

2013 ◽

Author(s):

Burton Eisenberg

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Phase I Study ◽

Pediatric Patients ◽

Phase I–II Vinorelbine (Navelbine®) by Continuous Infusion in Patients with Metastatic Breast Cancer: Cumulative Toxicities Limit Dose Escalation

Cancer Investigation ◽

10.1081/cnv-100103844 ◽

2001 ◽

Vol 19 (5) ◽

pp. 459-466 ◽

Cited By ~ 6

Author(s):

Nuhad K. Ibrahim ◽

Vicente Valero ◽

Zia Rahman ◽

Richard L. Theriault ◽

Ronald S. Walters ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Continuous Infusion ◽

Dose Escalation ◽

Metastatic Breast

116 A phase I clinical trial to evaluate the pharmacokinetics, toxicity and dosimetry of 111-indium-labeled human epidermal growth factor in patients with metastatic breast cancer

Radiotherapy and Oncology ◽

10.1016/s0167-8140(05)80277-4 ◽

2005 ◽

Vol 76 ◽

pp. S35

Author(s):

K. Vallis ◽

R. Reilley ◽

D. Scollard ◽

J. Petronis ◽

C. Caldwell ◽

...

Keyword(s):

Breast Cancer ◽

Clinical Trial ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Metastatic Breast ◽

Phase I Clinical Trial ◽

Human Epidermal Growth Factor ◽

Epidermal Growth

A phase I dose-escalating study of DaunoXome, liposomal daunorubicin, in metastatic breast cancer

British Journal of Cancer ◽

10.1038/sj.bjc.6600344 ◽

2002 ◽

Vol 87 (1) ◽

pp. 15-20 ◽

Cited By ~ 48

Author(s):

K J O'Byrne ◽

A L Thomas ◽

R A Sharma ◽

M DeCatris ◽

F Shields ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Metastatic Breast ◽

Liposomal Daunorubicin ◽

Dose Escalating

A Phase I Study of Quisinostat (JNJ-26481585), an Oral Hydroxamate Histone Deacetylase Inhibitor with Evidence of Target Modulation and Antitumor Activity, in Patients with Advanced Solid Tumors

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-13-0312 ◽

2013 ◽

Vol 19 (15) ◽

pp. 4262-4272 ◽

Cited By ~ 63

Author(s):

Balaji Venugopal ◽

Richard Baird ◽

Rebecca S. Kristeleit ◽

Ruth Plummer ◽

Richard Cowan ◽

...

Keyword(s):

Antitumor Activity ◽

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Phase I Study ◽

Advanced Solid Tumors ◽

Phase I study of JAK1/2 inhibitor ruxolitinib with weekly paclitaxel for the treatment of HER2-negative metastatic breast cancer

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-021-04245-x ◽

2021 ◽

Author(s):

Filipa Lynce ◽

James T. Williams ◽

Meredith M. Regan ◽

Craig A. Bunnell ◽

Rachel A. Freedman ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Phase I Study ◽

Metastatic Breast ◽

Weekly Paclitaxel

A Phase I Study of Pemetrexed (ALIMTA) and Cyclophosphamide in Patients with Locally Advanced or Metastatic Breast Cancer

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-05-2829 ◽

2006 ◽

Vol 12 (23) ◽

pp. 7071-7078 ◽

Cited By ~ 10

Author(s):

Christian Dittrich ◽

Lubos Petruzelka ◽

Pavel Vodvarka ◽

Margit Gneist ◽

Filip Janku ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Phase I Study ◽

Locally Advanced ◽

Metastatic Breast