Crosstalk to Stromal Fibroblasts Induces Resistance of Lung Cancer to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-09-1001 ◽

2009 ◽

Vol 15 (21) ◽

pp. 6630-6638 ◽

Author(s):

W. Wang ◽

Q. Li ◽

T. Yamada ◽

K. Matsumoto ◽

I. Matsumoto ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Stromal Fibroblasts ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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Three generations of epidermal growth factor receptor tyrosine kinase inhibitors developed to revolutionize the therapy of lung cancer

Drug Design Development and Therapy ◽

10.2147/dddt.s119162 ◽

2016 ◽

Vol Volume 10 ◽

pp. 3867-3872 ◽

Author(s):

Haijun Zhang

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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Clinical Significance of Heterogeneity in Response to Retreatment With Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With Lung Cancer Acquiring Secondary Resistance to the Drug

Clinical Lung Cancer ◽

10.1016/j.cllc.2013.11.008 ◽

2014 ◽

Vol 15 (2) ◽

pp. 145-151 ◽

Author(s):

Youngjoo Lee ◽

Hyae Young Kim ◽

Soo-Hyun Lee ◽

Kun Young Lim ◽

Geon Kook Lee ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Secondary Resistance ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer

Cancer Science ◽

10.1111/j.1349-7006.2007.00607.x ◽

2007 ◽

Vol 98 (12) ◽

pp. 1817-1824 ◽

Author(s):

Tetsuya Mitsudomi ◽

Yasushi Yatabe

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Receptor Gene ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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Biomarkers of Sensitivity for the Treatment of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Lung Cancer

Haigan ◽

10.2482/haigan.49.934 ◽

2009 ◽

Vol 49 (6) ◽

pp. 934-938

Author(s):

Kenji Sugio

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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PD 0332991, a selective cyclin D kinase 4/6 inhibitor, sensitizes lung cancer cells to treatment with epidermal growth factor receptor tyrosine kinase inhibitors

10.18632/oncotarget.13069 ◽

2016 ◽

Vol 7 (51) ◽

pp. 84951-84964 ◽

Author(s):

Minghui Liu ◽

Song Xu ◽

Yuli Wang ◽

Ying Li ◽

Yongwen Li ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Cyclin D ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors

Cancer ◽

10.1002/cncr.26656 ◽

2012 ◽

Vol 118 (16) ◽

pp. 3993-4003 ◽

Author(s):

Woo-Young Kim ◽

Ludmila Prudkin ◽

Lei Feng ◽

Edward S. Kim ◽

Bryan Hennessy ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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The Role of Epidermal Growth Factor Receptor Mutations and Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in the Treatment of Lung Cancer

Cancers ◽

10.3390/cancers3022667 ◽

2011 ◽

Vol 3 (2) ◽

pp. 2667-2678 ◽

Author(s):

Shih-Chieh Chang ◽

Cheng-Yu Chang ◽

Jin-Yuan Shih

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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Epidermal growth factor receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer

Current Opinion in Oncology ◽

10.1097/cco.0000000000000495 ◽

2019 ◽

Vol 31 (1) ◽

pp. 1-7 ◽

Author(s):

Julia Roeper ◽

Frank Griesinger

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Nonsmall Cell Lung Cancer ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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Oncogenic drivers in nonsmall cell lung cancer and resistance to epidermal growth factor receptor tyrosine kinase inhibitors

Indian Journal of Cancer ◽

10.4103/ijc.ijc_505_17 ◽

2017 ◽

Vol 54 (5) ◽

pp. 1 ◽

Author(s):

A Pathak ◽

S Rajappa ◽

A Gore

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Nonsmall Cell Lung Cancer ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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PTEN inactivation in lung cancer cells and the effect of its recovery on treatment with epidermal growth factor receptor tyrosine kinase inhibitors

International Journal of Oncology ◽

10.3892/ijo.31.5.1157 ◽

2007 ◽

Author(s):

Shoji Kudoh ◽

Akinobu Yoshimura ◽

Kiyoko Kataoka ◽

Kuniko Matsuda ◽

Tetsuya Okano ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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