scholarly journals Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression

2009 ◽  
Vol 15 (19) ◽  
pp. 6113-6127 ◽  
Author(s):  
A.K.M. Ghulam Muhammad ◽  
Marianela Candolfi ◽  
Gwendalyn D. King ◽  
Kader Yagiz ◽  
David Foulad ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Cellular Immunity ◽  
Tumor Regression ◽  
Immunological Memory ◽  
Humoral And Cellular Immunity

Adenovirus-mediated CD40L gene therapy induced both humoral and cellular immunity against rat model of hepatocellular carcinoma

2008 ◽  
Author(s):  
Tomonori Iida ◽  
Hiroaki Shiba ◽  
Takeyuki Misawa ◽  
Toya Ohashi ◽  
Yoshikatsu Eto ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gene Therapy ◽  
Cellular Immunity ◽  
Rat Model ◽  
Humoral And Cellular Immunity

Adenovirus-mediated CD40L gene therapy induced both humoral and cellular immunity against rat model of hepatocellular carcinoma

2008 ◽  
Vol 99 (10) ◽  
pp. 2097-2103 ◽  
Author(s):  
Tomonori Iida ◽  
Hiroaki Shiba ◽  
Takeyuki Misawa ◽  
Toya Ohashi ◽  
Yoshikatsu Eto ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gene Therapy ◽  
Cellular Immunity ◽  
Rat Model ◽  
Humoral And Cellular Immunity

scholarly journals Long-lasting cellular immunity to SARS-CoV-2 following infection or vaccination and implications for booster strategies

2021 ◽  
Author(s):  
Alessio Mazzoni ◽  
Anna Vanni ◽  
Michele Spinicci ◽  
Giulia Lamacchia ◽  
Seble Tekle Kiros ◽  
...  
Keyword(s):  
Cellular Immunity ◽  
Booster Dose ◽  
Natural Infection ◽  
Severe Disease ◽  
Immunological Memory ◽  
Short Term ◽  
Humoral And Cellular Immunity ◽  
One Year ◽  
Antibody Levels ◽  
Kinetics Of

AbstractImmunization against SARS-CoV-2, the causative agent of coronavirus disease-19 (COVID-19) occurs via natural infection or vaccination. However, it is currently unknown how long infection- or vaccination-induced immunological memory will last. We performed a longitudinal evaluation of immunological memory to SARS-CoV-2 following mRNA vaccination in naïve and COVID-19 recovered individuals. We found that cellular immunity is still detectable 8 months after vaccination, while antibody levels decline significantly especially in naïve subjects. We also found that a booster injection is more efficacious in reactivating immunological memory to spike protein in naïve than in previously SARS-CoV-2 infected subjects. Finally, we observed a similar kinetics of decay of humoral and cellular immunity to SARS-CoV-2 up to one year following natural infection in a cohort of unvaccinated individuals. Short-term persistence of humoral immunity may account for reinfections and breakthrough infections, although long-lived memory B and CD4+ T cells may protect from severe disease. A booster dose restores optimal anti-spike immunity in naïve subjects, while the need for vaccinated COVID-19 recovered subjects has yet to be defined.

scholarly journals SARS‐CoV‐2‐specific humoral and cellular immunity in two renal transplants and two hemodialysis patients treated with convalescent plasma

2021 ◽  
Author(s):  
Monika Lindemann ◽  
Adalbert Krawczyk ◽  
Sebastian Dolff ◽  
Margarethe Konik ◽  
Hana Rohn ◽  
...  
Keyword(s):  
Cellular Immunity ◽  
Hemodialysis Patients ◽  
Renal Transplants ◽  
Humoral And Cellular Immunity

Humoral and Cellular Immunity to an Encoded Protein Induced by Direct DNA Injection

1994 ◽  
Vol 5 (11) ◽  
pp. 1335-1339 ◽  
Author(s):  
Akira Katsumi ◽  
Nobuhiko Emi ◽  
Akihiro Abe ◽  
Yoshinori Hasegawa ◽  
Masafumi Ito ◽  
...  
Keyword(s):  
Cellular Immunity ◽  
Humoral And Cellular Immunity ◽  
Dna Injection

Humoral and Cellular Immunity in Different Phases of Contact Dermatitis

1991 ◽  
Vol 2 (3) ◽  
pp. 187-191
Author(s):  
P. Torres ◽  
F. Guerra ◽  
A. Arenas ◽  
R. Miguel ◽  
C. Moreno ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Cellular Immunity ◽  
Humoral And Cellular Immunity

Endoscopic laserotherapy in combined treatment of duodenal peptic ulcerous disease

1999 ◽  
Vol 80 (3) ◽  
pp. 172-175
Author(s):  
S. N. Batrakov ◽  
V. N. Troshkin
Keyword(s):  
Mucous Membrane ◽  
Cellular Immunity ◽  
Combined Treatment ◽  
Traditional Treatment ◽  
Humoral And Cellular Immunity ◽  
Clinical Efficiency

The results of combined treatment of 90 patients with duodenal peptic ulcerous disease are presented. The clinical efficiency of complementing the traditional treatment by the endoscopic laserotherapy is shown. The positive dynamics of histamine, serotonin, catecholamines in duodenum mucous membrane was noted parallel with the clinicoendoscopic picture improvement. The positive changes of humoral and cellular immunity indices in the presence of the treatment combined with the endoscopic laserotherapy were observed.

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