A Bispecific Enediyne-Energized Fusion Protein Containing Ligand-Based and Antibody-Based Oligopeptides against Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 Shows Potent Antitumor Activity

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Fusion Protein ◽

Growth Factor Receptor ◽

Trastuzumab in combination with paclitaxel enhances antitumor activity by promoting apoptosis in human epidermal growth factor receptor 2-positive trastuzumab-resistant gastric cancer xenograft models

Anti-Cancer Drugs ◽

10.1097/cad.0000000000000853 ◽

2020 ◽

Vol 31 (3) ◽

pp. 241-250

Author(s):

Sei Shu ◽

Yoriko Yamashita-Kashima ◽

Mieko Yanagisawa ◽

Hayao Nakanishi ◽

Yasuhiro Kodera ◽

...

Keyword(s):

Gastric Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Xenograft Models ◽

Gastric Cancer Xenograft

Antitumor activity of a combination of trastuzumab (Herceptin) and oral fluoropyrimidine S-1 on human epidermal growth factor receptor 2-overexpressing pancreatic cancer

Oncology Reports ◽

10.3892/or.18.2.433 ◽

2007 ◽

Cited By ~ 1

Author(s):

Hiroyuki Saeki ◽

Shunsuke Yanoma ◽

Shouji Takemiya ◽

Yukio Sugimasa ◽

Makoto Akaike ◽

...

Keyword(s):

Pancreatic Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Growth Factor Receptor ◽

Oral Fluoropyrimidine ◽

Superior Antitumor Activity of a Novel Bispecific Antibody Cotargeting Human Epidermal Growth Factor Receptor 2 and Type I Insulin-like Growth Factor Receptor

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-13-0558 ◽

2013 ◽

Vol 13 (1) ◽

pp. 90-100 ◽

Cited By ~ 13

Author(s):

C. Chen ◽

Y. Zhang ◽

J. Li ◽

S. W. Tsao ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Bispecific Antibody ◽

Growth Factor Receptor ◽

Type I ◽

Insulin Like Growth Factor ◽

Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers

Breast Cancer Research ◽

10.1186/s13058-018-1023-x ◽

2018 ◽

Vol 20 (1) ◽

Cited By ~ 2

Author(s):

Takuya Osada ◽

Zachary C. Hartman ◽

Junping Wei ◽

Gangjun Lei ◽

Amy C. Hobeika ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Triple Negative ◽

Growth Factor Receptor ◽

Breast Cancers ◽

6-Substituted-4-(3-bromophenylamino)quinazolines as Putative Irreversible Inhibitors of the Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor (HER-2) Tyrosine Kinases with Enhanced Antitumor Activity

Journal of Medicinal Chemistry ◽

10.1021/jm0005555 ◽

2001 ◽

Vol 44 (17) ◽

pp. 2719-2734 ◽

Cited By ~ 189

Author(s):

Hwei-Ru Tsou ◽

Nellie Mamuya ◽

Bernard D. Johnson ◽

Marvin F. Reich ◽

Brian C. Gruber ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Tyrosine Kinases ◽

Growth Factor Receptor ◽

Irreversible Inhibitors ◽

Her 2 ◽

Preclinical antitumor activity of S ‐222611, an oral reversible tyrosine kinase inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2

Cancer Science ◽

10.1111/cas.12449 ◽

2014 ◽

Vol 105 (8) ◽

pp. 1040-1048 ◽

Cited By ~ 7

Author(s):

Hidekazu Tanaka ◽

Michinari Hirata ◽

Satomi Shinonome ◽

Toru Wada ◽

Motofumi Iguchi ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

An Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody H2Mab-19 Exerts Antitumor Activity in Mouse Colon Cancer Xenografts

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy ◽

10.1089/mab.2020.0009 ◽

2020 ◽

Vol 39 (4) ◽

pp. 123-128

Author(s):

Yukinari Kato ◽

Tomokazu Ohishi ◽

Junko Takei ◽

Takuro Nakamura ◽

Masato Sano ◽

...

Keyword(s):

Monoclonal Antibody ◽

Colon Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Growth Factor Receptor ◽

Mouse Colon ◽

Construction of an Ec-LDP-D5 fusion protein that targets human epidermal growth factor receptor and its anti-pancreatic cancer activity

Precision Radiation Oncology ◽

10.1002/pro6.17 ◽

2017 ◽

Vol 1 (2) ◽

pp. 64-69

Author(s):

Wen-juan Liu ◽

Xian-rang Song ◽

Bin-li Zuo ◽

Xing-wu Wang

Keyword(s):

Pancreatic Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Fusion Protein ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Cancer Activity

H2Mab‑19, an anti‑human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts

Experimental and Therapeutic Medicine ◽

10.3892/etm.2020.8765 ◽

2020 ◽

Vol 20 (2) ◽

pp. 846-853

Author(s):

Junko Takei ◽

Mika Kaneko ◽

Tomokazu Ohishi ◽

Manabu Kawada ◽

Hiroyuki Harada ◽

...

Keyword(s):

Monoclonal Antibody ◽

Growth Factor ◽

Oral Cancer ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Growth Factor Receptor ◽

Construction of a novel fusion protein harboring mouse interferon γ and epidermal growth factor receptor binding domain and enhancement of its antitumor activity

Science in China Series C Life Sciences ◽

10.1007/bf02879090 ◽

1997 ◽

Vol 40 (3) ◽

pp. 293-300 ◽

Cited By ~ 1

Author(s):

Yanping Ding ◽

Weiyan Tan ◽

Rong Hu ◽

Wangqiu Chen ◽

Yunde Hou

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Fusion Protein ◽

Receptor Binding ◽

Growth Factor Receptor ◽

Interferon Γ ◽

Receptor Binding Domain ◽