scholarly journals A Novel Small Molecule Aurora Kinase Inhibitor Attenuates Breast Tumor–Initiating Cells and Overcomes Drug Resistance

2014 ◽  
Vol 13 (8) ◽  
pp. 1991-2003 ◽  
Author(s):  
Fei-Meng Zheng ◽  
Zi-Jie Long ◽  
Zhi-Jie Hou ◽  
Yu Luo ◽  
Ling-Zhi Xu ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Small Molecule ◽  
Breast Tumor ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor ◽  
Tumor Initiating Cells

Gender Effects on Rat Metabolism of AMG 900, an Orally Available Small Molecule Aurora Kinase Inhibitor

2011 ◽  
Vol 5 (4) ◽  
pp. 290-297 ◽  
Author(s):  
Daniel Waldon ◽  
Loren Berry ◽  
Min-Hwa Jasmine Lin ◽  
Laurie Schenkel ◽  
L. Steven Hollis ◽  
...  
Keyword(s):  
Small Molecule ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Gender Effects ◽  
Aurora Kinase Inhibitor

W1946 A Novel Small-Molecule Aurora Kinase Inhibitor with Strong Antiproliferative Activity in Human Carcinoid Cell Lines

2008 ◽  
Vol 134 (4) ◽  
pp. A-740
Author(s):  
Daniel Benten ◽  
Katharina Fraedrich ◽  
Jorg Schrader ◽  
Gunhild Keller ◽  
Arthur Gontarewicz ◽  
...  
Keyword(s):  
Cell Lines ◽  
Small Molecule ◽  
Antiproliferative Activity ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor

Ein neuer small-molecule Aurora Kinase Inhibitor zeigt starke antiproliferative Aktivität in humanen HCC Zelllinien

2008 ◽  
Vol 46 (01) ◽  
Author(s):  
D Benten ◽  
A Gontarewicz ◽  
G Keller ◽  
A Quaas ◽  
S Balabanov ◽  
...  
Keyword(s):  
Small Molecule ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor

321 A NOVEL SMALL-MOLECULE AURORA KINASE INHIBITOR WITH STRONG ANTIPROLIFERATIVE ACTIVITY IN HUMAN HCC CELL LINES

2008 ◽  
Vol 48 ◽  
pp. S127
Author(s):  
D. Benten ◽  
G. Keller ◽  
A. Gontarewicz ◽  
A. Quaas ◽  
S. Balabanov ◽  
...  
Keyword(s):  
Cell Lines ◽  
Small Molecule ◽  
Antiproliferative Activity ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor

scholarly journals PF-03814735, an Orally Bioavailable Small Molecule Aurora Kinase Inhibitor for Cancer Therapy

2010 ◽  
Vol 9 (4) ◽  
pp. 883-894 ◽  
Author(s):  
Jitesh P. Jani ◽  
Joel Arcari ◽  
Vincent Bernardo ◽  
Samit K. Bhattacharya ◽  
David Briere ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Small Molecule ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor ◽  
Orally Bioavailable

scholarly journals The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing

2013 ◽  
Vol 62 ◽  
pp. 777-784 ◽  
Author(s):  
Stefan O. Ochiana ◽  
Vidya Pandarinath ◽  
Zhouxi Wang ◽  
Rishika Kapoor ◽  
Mary Jo Ondrechen ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Lead Compound ◽  
Aurora Kinase Inhibitor ◽  
Target Repurposing

A phase l study of three different dosing schedules of the oral aurora kinase inhibitor MSC1992371A in patients with solid tumors

2013 ◽  
Vol 9 (3) ◽  
pp. 215-224 ◽  
Author(s):  
M. Mita ◽  
M. Gordon ◽  
N. Rejeb ◽  
A. Gianella-Borradori ◽  
V. Jego ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor
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