Abstract 4872: Synergistic induction of cell death and apoptosis by the histone deacetylase inhibitor vorinostat and the demethylating agent 5-aza-2′-deoxycytidine in multiple myeloma

2010 ◽  
Author(s):  
Edgar Jost ◽  
Claudia Schubert ◽  
Tim H. Brümmendorf ◽  
Oliver Galm
Keyword(s):  
Multiple Myeloma ◽  
Cell Death ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Demethylating Agent ◽  
Deacetylase Inhibitor ◽  
Synergistic Induction

A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways

2009 ◽  
Vol 20 (9) ◽  
pp. 815-821 ◽  
Author(s):  
Jung Jin Hwang ◽  
Yong Sook Kim ◽  
Mi Joung Kim ◽  
Sejin Jang ◽  
Je-Hwan Lee ◽  
...  
Keyword(s):  
Cell Death ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Deacetylase Inhibitor ◽  
Intrinsic Apoptotic Pathways ◽  
Apoptotic Pathways

Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells

2010 ◽  
Vol 30 (2) ◽  
pp. 435-442 ◽  
Author(s):  
Eun-Taex Oh ◽  
Moon-Taek Park ◽  
Bo-Hwa Choi ◽  
Seonggu Ro ◽  
Eun-Kyung Choi ◽  
...  
Keyword(s):  
Cell Death ◽  
Cancer Cells ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Deacetylase Inhibitor ◽  
Clonogenic Cell

scholarly journals Phase 2 trial of the histone deacetylase inhibitor romidepsin for the treatment of refractory multiple myeloma

Cancer ◽  
2010 ◽  
Vol 117 (2) ◽  
pp. 336-342 ◽  
Author(s):  
Ruben Niesvizky ◽  
Scott Ely ◽  
Tomer Mark ◽  
Sangeeta Aggarwal ◽  
Janice L Gabrilove ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Phase 2 ◽  
Refractory Multiple Myeloma ◽  
Phase 2 Trial ◽  
Deacetylase Inhibitor

scholarly journals CREB-Binding Protein Is a Mediator of Neuroblastoma Cell Death Induced By the Histone Deacetylase Inhibitor Trichostatin A

Neoplasia ◽  
2007 ◽  
Vol 9 (6) ◽  
pp. 495-503 ◽  
Author(s):  
Chitra Subramanian ◽  
Jason A. Jarzembowski ◽  
Anthony W. Opipari ◽  
Valerie P. Castle ◽  
Roland P.S. Kwok
Keyword(s):  
Cell Death ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Binding Protein ◽  
Trichostatin A ◽  
Neuroblastoma Cell ◽  
Creb Binding Protein ◽  
Deacetylase Inhibitor ◽  
Histone Deacetylase Inhibitor Trichostatin
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