Abstract 2053: F-XA7, a novel derivative of vinca alkaloid with potent antitumor activity, efficiently overrides P-glycoprotein-mediated drug resistance bothin vitroandin vivo.

2013 ◽  
Author(s):  
Haitian Quan ◽  
Yongping Xu ◽  
Lihong Hu ◽  
Liguang Lou
Keyword(s):  
Drug Resistance ◽  
Antitumor Activity ◽  
Vinca Alkaloid ◽  
P Glycoprotein

Histone deacetylase inhibitor apicidin-mediated drug resistance: Involvement of P-glycoprotein

2008 ◽  
Vol 368 (4) ◽  
pp. 959-964 ◽  
Author(s):  
Yong Kee Kim ◽  
Nam Hyun Kim ◽  
Jee Won Hwang ◽  
Yong-Jin Song ◽  
Yeon-Suk Park ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
P Glycoprotein ◽  
Deacetylase Inhibitor

Discovery of a Daunorubicin Analogue That Exhibits Potent Antitumor Activity and Overcomes P-gp-Mediated Drug Resistance

2006 ◽  
Vol 49 (3) ◽  
pp. 932-941 ◽  
Author(s):  
Lanyan Fang ◽  
Guisheng Zhang ◽  
Chenglong Li ◽  
Xincheng Zheng ◽  
Lizhi Zhu ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antitumor Activity

Etanercept overcomes P-glycoprotein-induced drug resistance in lymphocytes of patients with intractable rheumatoid arthritis

2010 ◽  
Vol 20 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Shizuyo Tsujimura ◽  
Kazuyoshi Saito ◽  
Shingo Nakayamada ◽  
Yoshiya Tanaka
Keyword(s):  
Rheumatoid Arthritis ◽  
Drug Resistance ◽  
P Glycoprotein

Synthesis and Biological Evaluation of C-Aromataxane Derivatives as P-Glycoprotein-Mediated Multi Drug Resistance Reversal Agents

Heterocycles ◽  
2015 ◽  
Vol 90 (1) ◽  
pp. 482
Author(s):  
Takayuki Doi ◽  
Naoko Yamaguchi ◽  
Kosuke Ohsawa ◽  
Kazuoki Nakai ◽  
Masahito Yoshida ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Biological Evaluation ◽  
Multi Drug Resistance ◽  
Reversal Agents ◽  
P Glycoprotein ◽  
Resistance Reversal ◽  
Synthesis And Biological Evaluation

scholarly journals CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination

Oncotarget ◽  
2015 ◽  
Vol 6 (28) ◽  
pp. 26308-26321 ◽  
Author(s):  
Abhilash K. Ravindranath ◽  
Swayamjot Kaur ◽  
Roman P. Wernyj ◽  
Muthu N. Kumaran ◽  
Karl E. Miletti-Gonzalez ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Multi Drug Resistance ◽  
P Glycoprotein
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