Abstract 617: High-throughput screens identify PARP inhibition as being synthetically lethal with ERCC1 deficiency in non-small cell lung cancer cell lines.

2013 ◽  
Author(s):  
Sophie C. Postel-Vinay ◽  
Ilirjana Bajrami ◽  
Luc Friboulet ◽  
Marieke Aarts ◽  
Yari Fontebasso ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lines ◽  
High Throughput ◽  
Small Cell ◽  
Parp Inhibition ◽  
Lung Cancer Cell ◽  
Small Cell Lung ◽  
Synthetically Lethal ◽  
High Throughput Screens

APR-246 (PRIMA-1 MET ) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

2016 ◽  
Vol 375 (2) ◽  
pp. 313-322 ◽  
Author(s):  
Christophe Deben ◽  
Filip Lardon ◽  
An Wouters ◽  
Ken Op de Beeck ◽  
Jolien Van den Bossche ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cell Lung Cancer ◽  
Cancer Cell Lines ◽  
Small Cell ◽  
Parp Inhibition ◽  
Lung Cancer Cell ◽  
Small Cell Lung

scholarly journals Non-small-cell lung cancer cell lines A549 and NCI-H460 express hypoxanthine guanine phosphoribosyltransferase on the plasma membrane

2017 ◽  
Vol Volume 10 ◽  
pp. 1921-1932 ◽  
Author(s):  
Michelle Townsend ◽  
Michael Anderson ◽  
Evita Weagel ◽  
Edwin Velazquez ◽  
K. Scott Weber ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Plasma Membrane ◽  
Small Cell Lung Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lung Cancer Cell ◽  
Small Cell Lung ◽  
Hypoxanthine Guanine Phosphoribosyltransferase
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