Abstract 3809: Evaluation of the novel, orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 (verdinexor) in spontaneous canine cancer: Results of phase I and phase II clinical trials

2014 ◽  
Author(s):  
Cheryl A. London ◽  
Luis Feo Bernabe ◽  
Sandra Barnard ◽  
William Kisseberth ◽  
Antonella Borgatti ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Phase I ◽  
Phase Ii ◽  
Nuclear Export ◽  
Selective Inhibitor ◽  
The Novel ◽  
Phase Ii Clinical Trials ◽  
Canine Cancer ◽  
Orally Bioavailable

scholarly journals Preclinical Evaluation of the Novel, Orally Bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in Spontaneous Canine Cancer: Results of a Phase I Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e87585 ◽  
Author(s):  
Cheryl A. London ◽  
Luis Feo Bernabe ◽  
Sandra Barnard ◽  
William C. Kisseberth ◽  
Antonella Borgatti ◽  
...  
Keyword(s):  
Phase I ◽  
Nuclear Export ◽  
Phase I Study ◽  
Selective Inhibitor ◽  
The Novel ◽  
Preclinical Evaluation ◽  
Canine Cancer ◽  
Orally Bioavailable

scholarly journals Phase I and phase II clinical trials in sarcoma: Implications for drug discovery and development

2019 ◽  
Vol 8 (2) ◽  
pp. 585-592 ◽  
Author(s):  
Daniel Y. Lee ◽  
Arthur P. Staddon ◽  
Jacob E. Shabason ◽  
Ronnie Sebro
Keyword(s):  
Clinical Trials ◽  
Drug Discovery ◽  
Phase I ◽  
Phase Ii ◽  
Drug Discovery And Development ◽  
Phase Ii Clinical Trials

scholarly journals Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines

2014 ◽  
Vol 10 (1) ◽  
pp. 160 ◽  
Author(s):  
Megan N Breit ◽  
William C Kisseberth ◽  
Misty D Bear ◽  
Yosef Landesman ◽  
Trinayan Kashyap ◽  
...  
Keyword(s):  
Cell Lines ◽  
Melanoma Cell ◽  
Nuclear Export ◽  
Selective Inhibitor ◽  
The Novel ◽  
Biologic Activity ◽  
Orally Bioavailable ◽  
Canine Melanoma ◽  
Melanoma Cell Lines

scholarly journals Promising investigational drug candidates in phase I and phase II clinical trials for mesothelioma

2017 ◽  
Vol 26 (8) ◽  
pp. 933-944 ◽  
Author(s):  
Alice Guazzelli ◽  
Emyr Bakker ◽  
Kun Tian ◽  
Constantinos Demonacos ◽  
Marija Krstic-Demonacos ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Phase I ◽  
Phase Ii ◽  
Investigational Drug ◽  
Drug Candidates ◽  
Phase Ii Clinical Trials

scholarly journals New Peptide-Based Cancer Vaccine: Phase I and Early Phase II Clinical Trials for Castration-Resistant Prostate Cancer

2012 ◽  
Vol 23 ◽  
pp. xi74
Author(s):  
Masanori Noguchi ◽  
Shigetaka Suekane ◽  
Fukuko Moriya ◽  
Tetsuro Sasada ◽  
Akira Yamada ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Clinical Trials ◽  
Phase I ◽  
Phase Ii ◽  
Cancer Vaccine ◽  
Early Phase ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant ◽  
Phase Ii Clinical Trials
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