Abstract 3246: Novel luciferase labelling technique to improve imaging of orthotopic prostate and pancreatic cancer models

2015 ◽  
Author(s):  
Jenni Bernoulli ◽  
Johanna Tuomela ◽  
Matthias Bozza ◽  
Katja M. Fagerlund ◽  
Mari I. Suominen ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Labelling Technique ◽  
Cancer Models

scholarly journals The Revolutionary Roads to Study Cell–Cell Interactions in 3D In Vitro Pancreatic Cancer Models

Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 930
Author(s):  
Donatella Delle Cave ◽  
Riccardo Rizzo ◽  
Bruno Sainz ◽  
Giuseppe Gigli ◽  
Loretta L. del Mercato ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Response ◽  
Three Dimensional ◽  
Cellular Models ◽  
Common Cancer ◽  
Cancer Models ◽  
Anti Cancer ◽  
Tumor Environment

Pancreatic cancer, the fourth most common cancer worldwide, shows a highly unsuccessful therapeutic response. In the last 10 years, neither important advancements nor new therapeutic strategies have significantly impacted patient survival, highlighting the need to pursue new avenues for drug development discovery and design. Advanced cellular models, resembling as much as possible the original in vivo tumor environment, may be more successful in predicting the efficacy of future anti-cancer candidates in clinical trials. In this review, we discuss novel bioengineered platforms for anticancer drug discovery in pancreatic cancer, from traditional two-dimensional models to innovative three-dimensional ones.

Tumor specific changes of the gut microbiome in distinct murine pancreatic cancer models

Pancreatology ◽  
2021 ◽  
Vol 21 ◽  
pp. S68-S69
Author(s):  
T. Kaune ◽  
H. Griesmann ◽  
K. Theuerkorn ◽  
M. Hämmerle ◽  
L. Borges ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Gut Microbiome ◽  
Cancer Models

Abstract PO-066: High uptake, retention, and in vivo activity of L-Annamycin in pancreatic cancer models

2021 ◽  
Author(s):  
Ya'an Kang ◽  
Rafal Zielinski ◽  
Roberto Cardenas Zuniga ◽  
Radjendirane Venugopal ◽  
Maria Poimenidou ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
High Uptake ◽  
Cancer Models

Correlation of molecular profiles with response to targeted drugs in pancreatic cancer models

2020 ◽  
Vol 138 ◽  
pp. S58-S59
Author(s):  
D. Behrens ◽  
R. Lawlor ◽  
C. Heeschen ◽  
B. Buettner ◽  
J. Siveke ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Targeted Drugs ◽  
Cancer Models ◽  
Molecular Profiles

Abstract C246: nab®‐paclitaxel targets tumor stroma and results, combined with gemcitabine, in high efficacy against pancreatic cancer models

2009 ◽  
Author(s):  
Anirban Maitra ◽  
N.V. Rajeshkumar ◽  
Michelle Rudek ◽  
Ignacio Garrido‐Laguna ◽  
Daniel Laheru ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Tumor Stroma ◽  
High Efficacy ◽  
Cancer Models

Abstract 2171: Activatable nanodelivery of high payload gemcitabine augments therapeutic efficacy in murine breast and pancreatic cancer models

2019 ◽  
Author(s):  
Samantha T. Tucci ◽  
Azadeh Kheirolomoom ◽  
Elizabeth S. Ingham ◽  
Lisa M. Mahakian ◽  
Sarah M. Tam ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Efficacy ◽  
Cancer Models ◽  
High Payload

scholarly journals Cavitation-induced release of liposomal chemotherapy in orthotopic murine pancreatic cancer models: A feasibility study

2019 ◽  
Vol 43 (6) ◽  
pp. 669-681
Author(s):  
Marine Camus ◽  
Ariane Vienne ◽  
Jean-Louis Mestas ◽  
Carlos Pratico ◽  
Carole Nicco ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Feasibility Study ◽  
Cancer Models
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