Abstract 2171: Activatable nanodelivery of high payload gemcitabine augments therapeutic efficacy in murine breast and pancreatic cancer models

2019 ◽  
Author(s):  
Samantha T. Tucci ◽  
Azadeh Kheirolomoom ◽  
Elizabeth S. Ingham ◽  
Lisa M. Mahakian ◽  
Sarah M. Tam ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Efficacy ◽  
Cancer Models ◽  
High Payload

Abstract 2171: Activatable nanodelivery of high payload gemcitabine augments therapeutic efficacy in murine breast and pancreatic cancer models

2019 ◽  
Author(s):  
Samantha T. Tucci ◽  
Azadeh Kheirolomoom ◽  
Elizabeth S. Ingham ◽  
Lisa M. Mahakian ◽  
Sarah M. Tam ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Efficacy ◽  
Cancer Models ◽  
High Payload

scholarly journals The Revolutionary Roads to Study Cell–Cell Interactions in 3D In Vitro Pancreatic Cancer Models

Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 930
Author(s):  
Donatella Delle Cave ◽  
Riccardo Rizzo ◽  
Bruno Sainz ◽  
Giuseppe Gigli ◽  
Loretta L. del Mercato ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Response ◽  
Three Dimensional ◽  
Cellular Models ◽  
Common Cancer ◽  
Cancer Models ◽  
Anti Cancer ◽  
Tumor Environment

Pancreatic cancer, the fourth most common cancer worldwide, shows a highly unsuccessful therapeutic response. In the last 10 years, neither important advancements nor new therapeutic strategies have significantly impacted patient survival, highlighting the need to pursue new avenues for drug development discovery and design. Advanced cellular models, resembling as much as possible the original in vivo tumor environment, may be more successful in predicting the efficacy of future anti-cancer candidates in clinical trials. In this review, we discuss novel bioengineered platforms for anticancer drug discovery in pancreatic cancer, from traditional two-dimensional models to innovative three-dimensional ones.

Tumor specific changes of the gut microbiome in distinct murine pancreatic cancer models

Pancreatology ◽  
2021 ◽  
Vol 21 ◽  
pp. S68-S69
Author(s):  
T. Kaune ◽  
H. Griesmann ◽  
K. Theuerkorn ◽  
M. Hämmerle ◽  
L. Borges ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Gut Microbiome ◽  
Cancer Models

Abstract PO-066: High uptake, retention, and in vivo activity of L-Annamycin in pancreatic cancer models

2021 ◽  
Author(s):  
Ya'an Kang ◽  
Rafal Zielinski ◽  
Roberto Cardenas Zuniga ◽  
Radjendirane Venugopal ◽  
Maria Poimenidou ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
High Uptake ◽  
Cancer Models

scholarly journals Vascular targeting by EndoTAG™-1 enhances therapeutic efficacy of conventional chemotherapy in lung and pancreatic cancer

2009 ◽  
Vol 126 (5) ◽  
pp. 1235-1245 ◽  
Author(s):  
Martin E. Eichhorn ◽  
Ivan Ischenko ◽  
Siiri Luedemann ◽  
Sebastian Strieth ◽  
Armine Papyan ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Efficacy ◽  
Vascular Targeting ◽  
Conventional Chemotherapy

scholarly journals Controllable Moderate Heating Enhances the Therapeutic Efficacy of Irreversible Electroporation for Pancreatic Cancer

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Chelsea M. Edelblute ◽  
James Hornef ◽  
Niculina I. Burcus ◽  
Thomas Norman ◽  
Stephen J. Beebe ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Efficacy ◽  
Irreversible Electroporation

Correlation of molecular profiles with response to targeted drugs in pancreatic cancer models

2020 ◽  
Vol 138 ◽  
pp. S58-S59
Author(s):  
D. Behrens ◽  
R. Lawlor ◽  
C. Heeschen ◽  
B. Buettner ◽  
J. Siveke ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Targeted Drugs ◽  
Cancer Models ◽  
Molecular Profiles
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