Abstract 2426: Effects of MEN2 mutations on RET receptor localization and function

Author(s):  
Eduardo Reyes-Alvarez ◽  
Brandy D. Hyndman ◽  
Lois M. Mulligan
2017 ◽  
Vol 13 (7S_Part_20) ◽  
pp. P989-P989
Author(s):  
Athena Ching Jung Wang ◽  
Ron Freund ◽  
Christina M. Coughlan ◽  
Esteban M. Lucero ◽  
Mark DellAcqua ◽  
...  

2014 ◽  
Vol 307 (2) ◽  
pp. E133-E140 ◽  
Author(s):  
Ellis R. Levin

Steroid receptors exist and function in multiple compartments of cells in most organs. Although the functions and nature of some of these receptors is being defined, important aspects of receptor localization and signaling to physiology and pathophysiology have been identified. In particular, extranuclear sex steroid receptors have been found in many normal cells and in epithelial tumors, where they enact signal transduction that impacts both nongenomic and genomic functions. Here, I focus on the progress made in understanding the roles of extranuclear estrogen receptors (ER) in physiology and pathophysiology. Extranuclear ER serve as a model to selectively intervene with novel receptor reagents to prevent or limit disease progression. Recent novel mouse models and membrane ER-selective agonists also provide a better understanding of receptor pool cross-talk that results in the overall integrative actions of sex steroids.


2012 ◽  
Vol 44 (4) ◽  
pp. 669-678 ◽  
Author(s):  
Paramita Ray ◽  
Laura Anne Mihalko ◽  
Nathaniel L. Coggins ◽  
Pranav Moudgil ◽  
Anna Ehrlich ◽  
...  

1991 ◽  
Vol 562 (2) ◽  
pp. 190-198 ◽  
Author(s):  
B.G. Dinger ◽  
L. Almaraz ◽  
T. Hirano ◽  
K. Yoshizaki ◽  
C. Gonzalez ◽  
...  

1998 ◽  
Vol 861 (1 ADVANCES IN S) ◽  
pp. 91-96 ◽  
Author(s):  
A. J. SLEIGHT ◽  
F. G. BOESS ◽  
M. BOS ◽  
A. BOURSON

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