Abstract B01: Multilevel interference with receptor-PI3K-mTORC1 signaling is key mechanism for anticancer activity of fatty acid synthase inhibitors

2016 ◽  
Author(s):  
Renate Wagner ◽  
Katharina Pröstling ◽  
Daniel Veigel ◽  
Gerald Stübiger ◽  
Michael Grusch ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Anticancer Activity ◽  
Fatty Acid Synthase ◽  
Mtorc1 Signaling

scholarly journals New Synthetic Inhibitors of Fatty Acid Synthase with Anticancer Activity

2012 ◽  
Vol 55 (11) ◽  
pp. 5013-5023 ◽  
Author(s):  
Carlos Turrado ◽  
Teresa Puig ◽  
Javier García-Cárceles ◽  
Marta Artola ◽  
Bellinda Benhamú ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Anticancer Activity ◽  
Fatty Acid Synthase

scholarly journals Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity

2009 ◽  
Vol 15 (24) ◽  
pp. 7608-7615 ◽  
Author(s):  
T. Puig ◽  
C. Turrado ◽  
B. Benhamu ◽  
H. Aguilar ◽  
J. Relat ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Anticancer Activity ◽  
Fatty Acid Synthase

scholarly journals (−)-Epigallocatechin 3-Gallate Synthetic Analogues Inhibit Fatty Acid Synthase and Show Anticancer Activity in Triple Negative Breast Cancer

Molecules ◽  
2018 ◽  
Vol 23 (5) ◽  
pp. 1160 ◽  
Author(s):  
Joan Crous-Masó ◽  
Sònia Palomeras ◽  
Joana Relat ◽  
Cristina Camó ◽  
Úrsula Martínez-Garza ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Anticancer Activity ◽  
Triple Negative Breast Cancer ◽  
Fatty Acid Synthase ◽  
Triple Negative ◽  
Synthetic Analogues

Discovery of fatty acid synthase inhibitors and their biosynthetic pathways by a novel target-directed genome mining strategy

Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
J Li ◽  
X Tang ◽  
JJ Zhang ◽  
EC O'Neill ◽  
SM Mantovani ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Synthase ◽  
Genome Mining ◽  
Biosynthetic Pathways ◽  
Novel Target
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