Enrichment of Fetal Nucleated Red Blood Cells from the Maternal Circulation for Prenatal Diagnosis: Experiences with Triple Density Gradient and MACS Based on More than 600 Cases

1998 ◽  
Vol 13 (5) ◽  
pp. 276-286 ◽  
Author(s):  
Dorothee Gänshirt ◽  
Frank W.M. Smeets ◽  
Angelika Dohr ◽  
Corinna Walde ◽  
Imke Steen ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Red Blood Cells ◽  
Density Gradient ◽  
Blood Cells ◽  
Maternal Circulation ◽  
Nucleated Red Blood Cells

Fetal nucleated red blood cells from CVS washings: an aid to development of first trimester non-invasive prenatal diagnosis

2001 ◽  
Vol 21 (10) ◽  
pp. 827-834 ◽  
Author(s):  
Lucille Voullaire ◽  
Panayiotis Ioannou ◽  
Sara Nouri ◽  
Robert Williamson
Keyword(s):  
Prenatal Diagnosis ◽  
Red Blood Cells ◽  
Blood Cells ◽  
First Trimester ◽  
Non Invasive ◽  
Nucleated Red Blood Cells

A high yield of fetal nucleated red blood cells isolated using optimal osmolality and a double-density gradient system

2007 ◽  
Vol 27 (13) ◽  
pp. 1245-1250 ◽  
Author(s):  
K. H. Kwon ◽  
Y. J. Jeon ◽  
H. S. Hwang ◽  
K. A. Lee ◽  
Y. J. Kim ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Density Gradient ◽  
Blood Cells ◽  
High Yield ◽  
Gradient System ◽  
Nucleated Red Blood Cells

Prenatal detection of trisomy 21 on nucleated red blood cells enriched from maternal circulation by using fluorescencein situ hybridization

2002 ◽  
Vol 22 (9) ◽  
pp. 836-839 ◽  
Author(s):  
Ilona Hromadnikova ◽  
Dana Hridelova ◽  
Bela Houbova ◽  
Jan Vavrinec ◽  
Josef Kofer ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Trisomy 21 ◽  
Fluorescencein Situ Hybridization ◽  
Maternal Circulation ◽  
Prenatal Detection ◽  
Nucleated Red Blood Cells

Frequency-enhanced transferrin receptor antibody-labelled microfluidic chip (FETAL-Chip) enables efficient enrichment of circulating nucleated red blood cells for non-invasive prenatal diagnosis

Lab on a Chip ◽  
2018 ◽  
Vol 18 (18) ◽  
pp. 2749-2756 ◽  
Author(s):  
Huimin Zhang ◽  
Yuanyuan Yang ◽  
Xingrui Li ◽  
Yuanzhi Shi ◽  
Bin Hu ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Red Blood Cells ◽  
Microfluidic Chip ◽  
Transferrin Receptor ◽  
Blood Cells ◽  
Receptor Antibody ◽  
Non Invasive ◽  
Nucleated Red Blood Cells

We proposed a FETAL-Chip for efficient enrichment of cNRBCs, which offers great potential for NIPD.

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