Visual Field Defects and Normal Nerve Fiber Layer: May They Coexist in Primary Open-Angle Glaucoma?

2000 ◽  
Vol 214 (2) ◽  
pp. 119-121 ◽  
Author(s):  
Renato De Natale ◽  
Michele Marraffa ◽  
Roberta Morbio ◽  
Laura Tomazzoli ◽  
Luciano Bonomi
2018 ◽  
Vol 80 (4) ◽  
pp. 25-31
Author(s):  
Austin R. Lifferth

Glaucoma is the leading cause of irreversible blindness worldwide and is projected to affect more than 79.6 million people by 2020, over 10% of whom will be bilaterally blind.1 This multifactorial progressive optic neuropathy causes characteristic retinal nerve fiber layer damage that will eventually lead to associated glaucomatous visual field defects if left untreated. Unfortunately, these visual field defects are difficult for the patient to detect until more advanced stages and, as a result, early glaucoma is usually asymptomatic.2 This paper presents a case that is consistent with population studies that suggest that as many as half of people with glaucoma are unaware that they have the disease.3


2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Ayesha Saba Naz ◽  
Aisha Qamar ◽  
Sama Ul Haque ◽  
Yawar Zaman ◽  
Faisal Faheem

Objectives: To calculate the anterior lamina cribrosa depth (ALCD) and lamina cribrosa thickness (LCT) in primary open angle glaucoma (POAG) patients and controls and to correlate lamina cribrosa (LC) parameters to retinal nerve fiber layer thickness (RNFLT) and visual field (VF) defects. Methods: The study was conducted from November 2018 to March 2019. A total of 60 correspondents (30 cases and 30 controls) were assessed for general ophthalmological investigations including intraocular pressure (IOP), axial length AXL, ophthalmoscopy, visual field (VF) testing and spectral domain ocular computed tomography (SDOCT). Results: The mean age of subjects was 62 years (Cases 67.30±1.2, controls 57.32±1.1) with more male participants. Intraocular pressure [IOP (19.85 ±1.4)], AXL (22.85 ± 1.6), VF defects (8.30 ± 4.5), RNFLT (72.58 ± 13.2) and LCT (162.51 ± 64.62) were statistically significant in POAG patients as compared to the controls. Conclusion: A thinner LC in POAG correlated significantly with the RNFLT and VF defects. LC anatomical parameters can be estimated with precision using SDOCT with enhanced depth imaging (EDI). doi: https://doi.org/10.12669/pjms.36.3.1553 How to cite this:Naz AS, Qamar A, Sama-Ul-Haque, Zaman Y, Faheem F. Association of lamina cribrosa morphometry with retinal nerve fiber layer loss and visual field defects in primary open angle glaucoma. Pak J Med Sci. 2020;36(3):---------. doi: https://doi.org/10.12669/pjms.36.3.1553 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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