The article describes the role of selenium in the humankind being. The analysis based on the published data shows that the biological synthesis is a perspective way to obtain an organic form of selenium, which can be used in dietary supplements. The ability of lactic acid bacteria (Lactobacillus acidophilus 412/307)to accumulate inorganic forms of selenium (selenites, selenates), turning them into organic forms, with purposeful trace element enrichment of culture medium is described in the article. The main organic forms of selenium, which are being used in the process of biotransformation from its inorganic forms by microorganisms, have been reorganized. The relationship between the increasing of concentrations of sodium selenite in the culture medium and the growth of biomass of lactic acid bacteria was established. It was found the depressing effect of increasing concentrations of sodium selenite on optical density rate. It was estabilished the optimal conditions for the maximum accumulation of selenium containing culture of lactic acid bacteria. The influence of selenium concentration on the lactic acid bacteria biomass accumulation was determined also by changing the values of optical density. Due to the obtained data, the selenium containing dietary supplement «Selenolakt» was created. The main microbiological indicators that characterize the quality of the obtained product are given. The content of organic form of selenium in products reaches –195 ± 1 mkg/g.
Dietary supplements based on selenium containing culture of lactic acid bacteria