In vitro IgG Synthesis by Peripheral Blood Lymphocytes of Multiple Sclerosis Patients and Normal Individuals

1983 ◽  
Vol 22 (2) ◽  
pp. 131-137 ◽  
Author(s):  
S.C. Rastogi ◽  
N.H. Birkeboek
2006 ◽  
Vol 171 (1-2) ◽  
pp. 156-162 ◽  
Author(s):  
E. Hallin ◽  
J. Mellergård ◽  
M. Vrethem ◽  
J. Ernerudh ◽  
C. Ekerfelt

2002 ◽  
Vol 124 (1-2) ◽  
pp. 93-100 ◽  
Author(s):  
Cecilia Rajda ◽  
Krisztina Bencsik ◽  
László Vécsei L ◽  
Jonas Bergquist

1983 ◽  
Vol 103 (2) ◽  
pp. 210-215 ◽  
Author(s):  
A. P. Weetman ◽  
A. M. McGregor ◽  
H. Campbell ◽  
J. H. Lazarus ◽  
H. K. Ibbertson ◽  
...  

Abstract. Several studies have suggested that iodide may increase thyroiditis and autoantibody synthesis. We have investigated the effect of iodide in vitro at physiologically relevant concentrations on immunoglobulin synthesis by normal human peripheral blood lymphocytes stimulated with pokeweed mitogen. Both the number of cells which synthesised IgG and the amount of IgG released into the culture supernatant increased significantly after culture in a medium with added iodide compared to a medium with added chloride. No effect of increasing concentrations of the added iodide from 10−3 mm to 10 mm was observed. These findings suggest that iodides may have a role in enhancing antibody synthesis which may be important when programmes of iodide supplementation are introduced into areas which are deficient.


Sign in / Sign up

Export Citation Format

Share Document