Total Parenteral Nutrition Is a Major Risk Factor for Central Venous Catheter-Related Bloodstream Infection in Colorectal Cancer Patients Receiving Postoperative Chemotherapy

2008 ◽  
Vol 41 (4) ◽  
pp. 341-345 ◽  
Author(s):  
M. Ishizuka ◽  
H. Nagata ◽  
K. Takagi ◽  
K. Kubota
2013 ◽  
Vol 98 (1) ◽  
pp. 88-93 ◽  
Author(s):  
Mitsuru Ishizuka ◽  
Hitoshi Nagata ◽  
Kazutoshi Takagi ◽  
Keiichi Kubota

Abstract The needleless closed system (NCS) has been disseminated in several clinical fields to prevent central venous catheter–related bloodstream infection (CVC-RBSI), in place of the conventional Luer cap system (LCS). The purpose of this study is to examine whether NCS is really superior to conventional LCS for prevention of CVC-RBSI. Between May 2002 and December 2008, 1767 patients received CVC in our department. The time interval from insertion to development of CVC-RBSI was compared retrospectively between selected patients who were treated using the conventional LCS (group 1, n = 89, before June 2006) and the NCS (group 2, n = 406, June 2006 and after). Kaplan-Meier analysis revealed no significant difference in the time interval from insertion to development of CVC-RBSI between the two groups. NCS does not reduce CVC-RBSI in adult colorectal cancer patients who undergo CVC insertion.


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