Some Effects of Dibutyryl Cyclic Adenosine Monophosphate (DBcAMP) on Rabbit Bone Marrow Cells in Culture: Cell Clumping and Cholinesterase Production

Oncology ◽  
1974 ◽  
Vol 30 (6) ◽  
pp. 517-528 ◽  
Author(s):  
Vincent F. Garry, jr. ◽  
Larrel W. Harris ◽  
John P. Petrali
1974 ◽  
Vol 23 (15) ◽  
pp. 2155-2163 ◽  
Author(s):  
Larrel W. Harris ◽  
Vincent F. Garry ◽  
Robert D. Moore

Blood ◽  
2002 ◽  
Vol 99 (7) ◽  
pp. 2617-2619 ◽  
Author(s):  
Heather N. Crans-Vargas ◽  
Elliot M. Landaw ◽  
Smita Bhatia ◽  
George Sandusky ◽  
Theodore B. Moore ◽  
...  

Cyclic adenosine monophosphate response-element binding protein (CREB) is a nuclear protein that regulates expression of genes that control cell proliferation, differentiation, and survival. To analyze CREB expression in leukemia cells, we conducted Western blot analysis of bone marrow cells obtained from patients with acute lymphoblastic leukemia, patients with acute myeloid leukemia, and patients without active leukemia. CREB was expressed at a higher frequency in bone marrow cells from patients with acute lymphoid or myeloid leukemia than in patients with leukemia remission or without leukemia. Our results indicate that CREB expression could be a useful marker for leukemia in patients with acute disease and suggest a role for CREB in leukemogenesis.


1969 ◽  
Vol 129 (6) ◽  
pp. 1261-1273 ◽  
Author(s):  
M. Richter ◽  
N. I. Abdou

Bone marrow cells obtained from rabbits of one allotype were injected into irradiated rabbits of a different allotype. The recipients were also injected with sheep red blood cells, and their spleen cells were tested for plaque-forming capacity 7 days later. Spleen cells of all recipients gave large numbers of plaques as did spleen cells incubated with antiserum, directed toward donor allotype. However, incubation of the recipient spleen cells with antiserum directed toward recipient allotype completely suppressed plaque formation. These results demonstrate that antibody-formation in irradiated recipients of transferred lymphoid cells is a property of the recipient animal and that the antibody-forming cell is relatively irradiation-resistant. It was also demonstrated that only viable normal bone marrow cells are capable of transferring antibody-forming capacity to irradiated recipient rabbits. Neither sonicates nor heat-killed preparations of normal rabbit bone marrow cells possessed this capacity.


1999 ◽  
Vol 17 (2) ◽  
pp. 98-107 ◽  
Author(s):  
Yasuko Koshihara ◽  
Shunji Kodama ◽  
Hideaki Ishibashi ◽  
Yoshiaki Azuma ◽  
Tomohiro Ohta ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document