Inhibition of Amyloid Precursor Protein Beta-Secretase Cleavage Site Affects Survival and Motor Functions of Amyotrophic Lateral Sclerosis Transgenic Mice

2012 ◽  
Vol 10 (1-4) ◽  
pp. 30-33 ◽  
Author(s):  
Polina Rabinovich-Toidman ◽  
Maria Becker ◽  
Beika Barbiro ◽  
Beka Solomon
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Cleavage Site ◽  
Precursor Protein ◽  
Motor Functions ◽  
Beta Secretase ◽  
Lateral Sclerosis

scholarly journals Amyloid precursor protein (APP) contributes to pathology in the SOD1G93A mouse model of amyotrophic lateral sclerosis

2012 ◽  
Vol 21 (17) ◽  
pp. 3871-3882 ◽  
Author(s):  
J. Barney Bryson ◽  
Carl Hobbs ◽  
Michael J. Parsons ◽  
Karen D. Bosch ◽  
Amelie Pandraud ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Mouse Model ◽  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Sod1g93a Mouse ◽  
Lateral Sclerosis

Elevated levels of amyloid precursor protein in muscle of patients with amyotrophic lateral sclerosis and a mouse model of the disease

2006 ◽  
Vol 34 (4) ◽  
pp. 444-450 ◽  
Author(s):  
Hannu Koistinen ◽  
Rab Prinjha ◽  
Peter Soden ◽  
Alex Harper ◽  
Steven J. Banner ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Mouse Model ◽  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Lateral Sclerosis

scholarly journals Soluble Beta-Amyloid Precursor Protein Is Related to Disease Progression in Amyotrophic Lateral Sclerosis

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e23600 ◽  
Author(s):  
Petra Steinacker ◽  
Lubin Fang ◽  
Jens Kuhle ◽  
Axel Petzold ◽  
Hayrettin Tumani ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Amyloid Precursor Protein ◽  
Disease Progression ◽  
Beta Amyloid ◽  
Precursor Protein ◽  
Lateral Sclerosis

Changes in Amyloid-  and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein

2013 ◽  
Vol 5 (194) ◽  
pp. 194re2-194re2 ◽  
Author(s):  
L. F. Maia ◽  
S. A. Kaeser ◽  
J. Reichwald ◽  
M. Hruscha ◽  
P. Martus ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Precursor Protein
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