On the Relationship between the Rate of Salivary Flow and Salivary Fluoride Clearance

2015 ◽  
Vol 49 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Ralph M. Duckworth ◽  
S. Jones
Keyword(s):  
Flow Rate ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Time Of Application ◽  
Saliva Flow Rate ◽  
Whole Saliva ◽  
Observed Behaviour ◽  
Saliva Flow ◽  
Unstimulated Whole Saliva ◽  
The Relationship

The amount of fluoride retained in the mouth following the application of dentifrices, mouthwashes, etc. may be important in determining their anticaries efficacy. In this study we investigated the relationship between the salivary flow rate and salivary fluoride clearance. Ten adults tested six mouthrinses, consisting of aqueous sodium fluoride solutions (0.013, 0.026 mol/l) with and without added sodium chloride (1.28 mol/l) or sucrose (0.44 mol/l), in a randomised order. Prior to each test, subjects swallowed, rinsed for 2 min with 2 ml water and then expectorated into a preweighed container to obtain a measure of initial saliva flow rate. Next, the procedure was repeated using one of the test rinses. Finally, samples of unstimulated whole saliva were collected for up to 3 h after each mouthrinse application and analysed for fluoride. Salivary fluoride concentrations were significantly lower after application of mouthrinses that contained either sucrose or NaCl, both of which compounds markedly enhanced salivary flow, than after the use of corresponding mouthrinses without any additive. Area under the salivary fluoride clearance curve (AUC) values were inversely correlated with salivary flow rate on an individual basis (p < 0.01). The observed behaviour could not be completely attributed to treatment dilution by saliva at the time of application.

Comparison of Whole Saliva Flow Rates and Mucin Concentrations in Healthy Caucasian Young and Aged Adults

1992 ◽  
Vol 71 (6) ◽  
pp. 1275-1278 ◽  
Author(s):  
M. Navazesh ◽  
R.A. Mulligan ◽  
V. Kipnis ◽  
P.A. Denny ◽  
P.C. Denny
Keyword(s):  
Flow Rate ◽  
Salivary Flow ◽  
Young Group ◽  
Salivary Flow Rate ◽  
Flow Rates ◽  
Aged Group ◽  
Whole Saliva ◽  
Saliva Flow

Unstimulated and chewing-stimulated whole saliva samples were obtained from 42 healthy Caucasians; 21 were between 18 and 35 years of age, and 21 between 65 and 83 years of age. The unstimulated salivary flow rate was significantly lower in the aged group, but the stimulated flow rate was significantly higher in the aged than in the young group. Both groups showed significantly increased flow during salivary stimulation. MG1 and MG2 concentrations in unstimulated and stimulated saliva samples were significantly lower in the aged group. There were no significant correlations between salivary flow rates and MG1 and MG2 concentrations.

Gender difference in unstimulated whole saliva flow rate and salivary gland sizes

2006 ◽  
Vol 51 (12) ◽  
pp. 1055-1060 ◽  
Author(s):  
H. Inoue ◽  
K. Ono ◽  
W. Masuda ◽  
Y. Morimoto ◽  
T. Tanaka ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Gender Difference ◽  
Flow Rate ◽  
Saliva Flow Rate ◽  
Whole Saliva ◽  
Saliva Flow ◽  
Unstimulated Whole Saliva

scholarly journals Influence of a Fed or Fasted State on the s-IgA Response to Prolonged Cycling in Active Men and Women

2009 ◽  
Vol 19 (3) ◽  
pp. 209-221 ◽  
Author(s):  
Judith E. Allgrove ◽  
Louise Geneen ◽  
Sarah Latif ◽  
Michael Gleeson
Keyword(s):  
Flow Rate ◽  
Immunoglobulin A ◽  
Secretion Rate ◽  
Saliva Flow Rate ◽  
Fasted State ◽  
Whole Saliva ◽  
Iga Response ◽  
Saliva Flow ◽  
Unstimulated Whole Saliva ◽  
Active Adults

This study investigated the effect of a fed or fasted state on the salivary immunoglobulin A (s-IgA) response to prolonged cycling. Using a randomized, crossover design, 16 active adults (8 men and 8 women) performed 2 hr of cycling on a stationary ergometer at 65% of maximal oxygen uptake on 1 occasion after an overnight fast (FAST) and on another occasion 2 hr after consuming a 2.2-MJ high-carbohydrate meal (FED). Timed, unstimulated whole saliva samples were collected immediately before ingestion of the meal, immediately preexercise, 5 min before cessation of exercise, immediately postexercise, and 1 hr postexercise. The samples were analyzed for s-IgA concentration, osmolality, and cortisol, and saliva flow rates were determined to calculate s-IgA secretion rate. Saliva flow rate decreased by 50% during exercise (p < .05), and s-IgA concentration increased by 42% (p < .05), but s-IgA secretion rate remained unchanged. There was a 37% reduction in s-IgA:osmolality postexercise (p < .05), and salivary cortisol increased by 68% (p < .05). There was no effect of FED vs. FAST on these salivary responses. The s-IgA concentration, secretion rate, and osmolality were found to be significantly lower in women than in men throughout the exercise protocol (p < .05); however, there was no difference between genders in saliva flow rate, s-IgA:osmolality ratio, or cortisol. These data demonstrate that a fed or fasted state 2 hr before exercise does not influence resting s-IgA or the response to prolonged cycling. Furthermore, these results show lower levels of s-IgA and osmolality in women than in men at rest.

scholarly journals Correlation Assessment of unstimulated whole saliva flow rate with anthropometric indices

2016 ◽  
Vol 28 (4) ◽  
pp. 134-141
Author(s):  
Maryam Rabiei ◽  
Mohsen Maddah ◽  
Maryam Ghamgosar ◽  
◽  
◽  
...  
Keyword(s):  
Flow Rate ◽  
Anthropometric Indices ◽  
Saliva Flow Rate ◽  
Whole Saliva ◽  
Saliva Flow ◽  
Unstimulated Whole Saliva

scholarly journals Reliability of Screening Methods to Diagnose Oral Dryness and Evaluate Saliva Secretion

2020 ◽  
Vol 8 (3) ◽  
pp. 102
Author(s):  
Takaharu Goto ◽  
Takahiro Kishimoto ◽  
Yuki Iwawaki ◽  
Keiko Fujimoto ◽  
Yuichi Ishida ◽  
...  
Keyword(s):  
Flow Rate ◽  
Correlation Coefficients ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Screening Methods ◽  
Systematic Bias ◽  
Saliva Secretion ◽  
Whole Saliva ◽  
Oral Dryness ◽  
Unstimulated Whole Saliva

In this study, we evaluated the reliability and reproducibility of widely implemented salivary flow rate and oral dryness tests. In experiment 1, twenty young and healthy Japanese participants volunteered to participate. For each participant, the oral moisture (OM) level, unstimulated whole saliva volume (U-WSV), and stimulated whole saliva volume (S-WSV) were measured at the same time on two separate days. In experiment 2, twenty-seven patients who were over 65 years of age volunteered to participate. The OM level and U-WSV were measured at the same time on two separate days. In Experiment 1, the intra-class correlation coefficients (ICCs) corresponding to the S-WSV, U-WSV, and OM level were 0.23, 0.28, and 0.16, respectively, for the young participants. In Experiment 2, the ICCs corresponding to the U-WSV/spitting and OM level were 0.83 and 0.12, respectively, for the older participants. The results of Bland–Altman analysis confirmed the absence of systematic error, with the exception of the OM level results in Experiment 2, which indicated systematic bias. In conclusion, we believe that there is currently no consistent and reliable screening test for assessing salivary flow rate and oral dryness, although the spitting test was determined to be highly reliable.

Unstimulated whole saliva flow rate in relation to sicca symptoms in Hungary

Oral Diseases ◽  
2008 ◽  
Vol 14 (5) ◽  
pp. 472-477 ◽  
Author(s):  
K Márton ◽  
M Madléna ◽  
J Bánóczy ◽  
G Varga ◽  
P Fejérdy ◽  
...  
Keyword(s):  
Flow Rate ◽  
Saliva Flow Rate ◽  
Whole Saliva ◽  
Sicca Symptoms ◽  
Saliva Flow ◽  
Unstimulated Whole Saliva
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