Three Variants of Glucose-Phosphate Isomerase Deficiency

2015 ◽  
pp. 25-28
Author(s):  
G. E. J. Staal ◽  
J. Van Biervliet ◽  
A. M. C. Vlug ◽  
J. W. N. Akkerman
Keyword(s):  
Glucose Phosphate Isomerase ◽  
Glucose Phosphate

Characterization of the 5′ end of the gene for human glucose phosphate isomerase (GPI)

Genomics ◽  
1990 ◽  
Vol 7 (4) ◽  
pp. 638-643 ◽  
Author(s):  
James I.H. Walker ◽  
Pelin Faik ◽  
Michael J. Morgan
Keyword(s):  
Glucose Phosphate Isomerase ◽  
Glucose Phosphate

Comparison of human and murine isolates of Schistosoma mansoni from Richard-Toll, Senegal, by isoelectric focusing

1997 ◽  
Vol 71 (2) ◽  
pp. 175-181 ◽  
Author(s):  
M. Sène ◽  
P. Brémond ◽  
J.P. Hervé ◽  
V.R. Southgate ◽  
B. Sellin ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Acid Phosphatase ◽  
Lactate Dehydrogenase ◽  
Schistosoma Mansoni ◽  
Isoelectric Focusing ◽  
Glucose Phosphate Isomerase ◽  
Glucose Phosphate ◽  
Enzyme Systems ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Arvicanthis Niloticus

AbstractStudies on human and murine isolates of Schistosoma mansoni, from Richard-Toll, Senegal, were carried out by isoelectric focusing in polyacrylamide gels. Seven enzyme systems; lactate dehydrogenase (LDH), malate dehydrogenase (MDH), glucose-6-phosphate dehydrogenase (G6PD), acid phosphatase (AcP), hexokinase (HK), glucose phosphate isomerase (GPI), and phosphoglucomutase (PGM), were used to compare the two isolates. All systems tested, apart from LDH, were found to be polymorphic for both isolates. Interestingly, one phenotype is more frequent than the remainder. The results show that there is no significant genetic variation between the S. mansoni isolates from man and the rodents, Arvicanthis niloticus and Mastomys huberti.

Glucose Phosphate Isomerase Deficiency as a Cause of Hydrops Fetalis

1987 ◽  
Vol 316 (5) ◽  
pp. 258-261 ◽  
Author(s):  
Yaddanapudi Ravindranath ◽  
Donald E. Paglia ◽  
Indira Warrier ◽  
William Valentine ◽  
Misae Nakatani ◽  
...  
Keyword(s):  
Hydrops Fetalis ◽  
Glucose Phosphate Isomerase ◽  
Glucose Phosphate

Analyzing Glucose Phosphate Isomerase Isozymes in Chimeric Mouse Tissues by Electrophoresis

2008 ◽  
Vol 2008 (10) ◽  
pp. pdb.prot4813-pdb.prot4813
Author(s):  
A. Nagy ◽  
M. Gertsenstein ◽  
K. Vintersten ◽  
R. Behringer
Keyword(s):  
Chimeric Mouse ◽  
Glucose Phosphate Isomerase ◽  
Glucose Phosphate ◽  
Mouse Tissues

Developmental profile of glucose phosphate isomerase allozymes in parthenogenetic and tetraploid mouse embryos

Development ◽  
1991 ◽  
Vol 112 (2) ◽  
pp. 471-476
Author(s):  
U. Petzoldt
Keyword(s):  
Blastocyst Stage ◽  
Mouse Strains ◽  
Glucose Phosphate Isomerase ◽  
Experimental Conditions ◽  
Glucose Phosphate ◽  
Embryonic Genome ◽  
Allele Type ◽  
Enzyme Molecules ◽  
Degree Of Degradation ◽  
Parthenogenetic Embryos

Glucose phosphate isomerase (GPI) allozymes were compared in eggs and embryos of the mouse strains C57BL/6-JHan (GPI-1BB) and 129/Sv (GPI-1AA) under different experimental conditions. The quantitative differences in eggs of the two strains disappeared by the blastocyst stage at day 4 to 5, both in fertilized and diploid parthenogenetic embryos. The degree of degradation of oocyte-coded enzyme molecules and the activation of the embryonic genome for GPI appeared to be equivalent in parthenogenetic embryos from heterozygous females when only one or other maternal allele type remained in the egg after meiosis. Also in tetraploid embryos, generated by electrofusion of homozygous fertilized eggs from the two strains, both genomes seemed to be activated at the same time at day 4; here, however, the GPI-1BB allozyme remained predominant up to day 6.

Investigation of the determinative state of the mouse inner cell mass

Development ◽  
1975 ◽  
Vol 33 (4) ◽  
pp. 979-990
Author(s):  
J. Rossant
Keyword(s):  
Inner Cell Mass ◽  
Cell Mass ◽  
In Utero ◽  
Glucose Phosphate Isomerase ◽  
Trophoblast Cells ◽  
Electrophoretic Variants ◽  
Glucose Phosphate

Inner cell masses (ICMs) were dissected from 3½- and 4½-day blastocysts and cultured in contact with 2½-day morulae. Blastocysts and morulae were homozygous for different electrophoretic variants of the enzyme glucose phosphate isomerase (GPI). Aggregation of ICMs and morulae was observed, and such aggregates were able to form blastocysts in vitro and morphologically normal foetuses in utero. GPI analysis of these conceptuses revealed that most were chimaeric. However, donor ICM-type isozyme was only detected in the embryonic and extra-embryonic fractions of the chimaeras and never in the trophoblastic fraction. Thus, ICM cells appear unable to form trophoblast derivatives even when exposed to ‘outside’ conditions as experienced by developing trophoblast cells. This is evidence that ICM cells, although not overtly differentiated, are determined by 3½ days.

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