scholarly journals Extranodal Natural Killer/T-Cell Lymphoma of the Nasal Type with Skin Metastases

2016 ◽  
Vol 9 (1) ◽  
pp. 1-5
Author(s):  
Fadi Al Akhrass ◽  
Brooklyn Hensley ◽  
Lillian Thomas ◽  
Raymond Elsoueidi

Extranodal natural killer/T-cell lymphoma (ENKL) of the nasal type is a rare, clinically aggressive disease. ENKL of the nasal type is often localized in the upper aerodigestive tract, including the nasal cavity, nasopharynx, paranasal sinuses, tonsils, hypopharynx and larynx, and usually presents as stage I/II. Extranasal involvement can occur, and a common site of extranasal involvement or metastatic disease includes the skin. Identifying skin metastases is important for the appropriate staging and treatment. We report a case of ENKL of the nasal type that presented with localized disease and subsequent skin lesions that were consistent with skin metastases.

2021 ◽  
pp. 014556132098764
Author(s):  
Anthony N. Eze ◽  
Adedoyin O. Kalejaiye

Extranodal natural killer (NK)/T-cell lymphoma, nasal type (NNKTL) is a rare and highly aggressive non-Hodgkin lymphoma originating from NK or γδ T cells infected by Epstein-Barr virus (EBV). In the United States, NNKTL is usually noted in people of Asian or Hispanic descent. Natural killer/T-cell lymphoma, nasal type commonly involves the upper aerodigestive tract, including the nasopharynx, nasal cavity, Waldeyer’s ring, and oropharynx. Extensive local destruction and invasion has been noted, especially of the paranasal sinuses, hard palate, and central nervous system; involvement of the nasolacrimal duct with dacryocystitis is yet to be reported. We report a rare case of a Hispanic man with extranodal NNKTL masquerading as persistent dacryocystitis and necrotizing sinusitis unresponsive to antibiotics and surgical intervention. An extensive background of necrosis and inflammation was noted on pathology, and additional analysis with immunohistochemistry and in situ hybridization after repeat biopsy were necessary for accurate diagnosis.


2016 ◽  
Vol 12 (2) ◽  
pp. 825-836 ◽  
Author(s):  
Hua Wang ◽  
Pengfei Li ◽  
Xinke Zhang ◽  
Zhongjun Xia ◽  
Yue Lu ◽  
...  

2019 ◽  
Vol 43 (7) ◽  
pp. 995-1004
Author(s):  
Chun-xiang Xiang ◽  
Zi-hang Chen ◽  
Sha Zhao ◽  
Li-min Gao ◽  
Qing Tao ◽  
...  

2010 ◽  
Vol 28 (6) ◽  
pp. e94-e95 ◽  
Author(s):  
Laura B. Pincus ◽  
James L. Zehnder ◽  
Isaac M. Neuhaus ◽  
Charalambos Andreadis ◽  
Timothy H. McCalmont

2009 ◽  
Vol 102 (8) ◽  
pp. 873-874
Author(s):  
Rawan G. Abu-Zeitoon ◽  
Fadi Abu-Shahin ◽  
Roger D. Smalligan ◽  
Agnes Hamati

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