scholarly journals Digitally Analyzed Conjunctival Redness: Does Repeated Conjunctival Provocation Intrinsically Cause Local Desensitization of the Eye?

2015 ◽  
Vol 168 (4) ◽  
pp. 277-284 ◽  
Author(s):  
Claas Gloistein ◽  
Anatoli Astvatsatourov ◽  
Silke Allekotte ◽  
Ralph Mösges
Keyword(s):  
Conjunctival Redness

scholarly journals Defining the Optimal Region of Interest for Hyperemia Grading in the Bulbar Conjunctiva

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
María Luisa Sánchez Brea ◽  
Noelia Barreira Rodríguez ◽  
Antonio Mosquera González ◽  
Katharine Evans ◽  
Hugo Pena-Verdeal
Keyword(s):  
Region Of Interest ◽  
Bulbar Conjunctiva ◽  
Ocular Diseases ◽  
Conjunctival Hyperemia ◽  
Limited Region ◽  
Computer Aided ◽  
Optimal Region ◽  
Regression Techniques ◽  
Grading Scale ◽  
Conjunctival Redness

Conjunctival hyperemia or conjunctival redness is a symptom that can be associated with a broad group of ocular diseases. Its levels of severity are represented by standard photographic charts that are visually compared with the patient’s eye. This way, the hyperemia diagnosis becomes a nonrepeatable task that depends on the experience of the grader. To solve this problem, we have proposed a computer-aided methodology that comprises three main stages: the segmentation of the conjunctiva, the extraction of features in this region based on colour and the presence of blood vessels, and, finally, the transformation of these features into grading scale values by means of regression techniques. However, the conjunctival segmentation can be slightly inaccurate mainly due to illumination issues. In this work, we analyse the relevance of different features with respect to their location within the conjunctiva in order to delimit a reliable region of interest for the grading. The results show that the automatic procedure behaves like an expert using only a limited region of interest within the conjunctiva.

scholarly journals A Rare Coexistence of Isolated Unilateral Conjunctival Telangiectasia and Retinal Vascular Tortuosity

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Hilal Kilinç Hekimsoy ◽  
Mehmet Ali Şekeroğlu
Keyword(s):  
Differential Diagnosis ◽  
Ocular Disease ◽  
Ophthalmological Examination ◽  
Vascular Tortuosity ◽  
Systemic Disorder ◽  
History Of ◽  
Underlying Causes ◽  
Retinal Vascular Tortuosity ◽  
Conjunctival Redness

A 55-year-old woman with no known systemic disorder and without any history of ocular disease, trauma, and surgery presented with a nonremitting conjunctival redness on her left eye that was existing since her childhood. On ophthalmological examination, an extremely rare coexistence of isolated unilateral bulbar conjunctival telangiectasia and ipsilateral retinal vascular tortuosity without any systemic and neuroradiological association was detected. We aimed to demonstrate this rare vascular coexistence and discuss differential diagnosis of the underlying causes.

Final Report on the Safety Assessment of Ammonium and Glyceryl Thioglycolates and Thioglycolic Acid

1991 ◽  
Vol 10 (1) ◽  
pp. 135-192 ◽  
Keyword(s):  
Safety Assessment ◽  
Thioglycolic Acid ◽  
Skin Testing ◽  
Test System ◽  
Final Report ◽  
Skin Contact ◽  
Test Conditions ◽  
Cosmetic Ingredients ◽  
Permanent Wave ◽  
Conjunctival Redness

Ammonium and Glyceryl Thioglycolates and Thioglycolic Acid are used predominantly in cosmetic permanent waving lotions at concentrations up to 15.4% (as Thioglycolic Acid). At use concentrations, these cosmetic ingredients are only slightly toxic in acute single oral and dermal exposures. In repeated dermal tests for extended periods of exposure, these ingredients were toxic. Commercial permanent wave products produced transient conjunctival redness to both rinsed and unrinsed eyes. The results of skin testing for irritation and sensitization of these Thioglycolates depends on the type of test system used. Under occlusive patch testing, the data indicate that these ingredients are cumulative irritants and possibly weak sensitizers, but not under semi-occlusive test conditions. In clinical patients, mainly hairdressers, Glyceryl Thioglycolate elicited allergic reactions at concentrations down to 0.25%. It is concluded that these cosmetic ingredients may be safely used at infrequent intervals. However, hairdressers should avoid skin contact.

Conjunctival Redness Response to Corneal Stimulation

2019 ◽  
Vol 96 (7) ◽  
pp. 507-512 ◽  
Author(s):  
Emmanuel B. Alabi ◽  
Trefford L. Simpson
Keyword(s):  
Conjunctival Redness

scholarly journals A Fully Automated Pipeline for a Robust Conjunctival Hyperemia Estimation

2021 ◽  
Vol 11 (7) ◽  
pp. 2978
Author(s):  
Nico Curti ◽  
Enrico Giampieri ◽  
Fabio Guaraldi ◽  
Federico Bernabei ◽  
Laura Cercenelli ◽  
...  
Keyword(s):  
Neural Network ◽  
Image Processing ◽  
Network Model ◽  
Neural Network Model ◽  
Automated Analysis ◽  
Conjunctival Hyperemia ◽  
Average Accuracy ◽  
Automated Pipeline ◽  
Spearman’S Correlation ◽  
Conjunctival Redness

Purpose: Many semi-automated and fully-automated approaches have been proposed in literature to improve the objectivity of the estimation of conjunctival hyperemia, based on image processing analysis of eyes’ photographs. The purpose is to improve its evaluation using faster fully-automated systems and independent by the human subjectivity. Methods: In this work, we introduce a fully-automated analysis of the redness grading scales able to completely automatize the clinical procedure, starting from the acquired image to the redness estimation. In particular, we introduce a neural network model for the conjunctival segmentation followed by an image processing pipeline for the vessels network segmentation. From these steps, we extract some features already known in literature and whose correlation with the conjunctival redness has already been proved. Lastly, we implemented a predictive model for the conjunctival hyperemia using these features. Results: In this work, we used a dataset of images acquired during clinical practice.We trained a neural network model for the conjunctival segmentation, obtaining an average accuracy of 0.94 and a corresponding IoU score of 0.88 on a test set of images. The set of features extracted on these ROIs is able to correctly predict the Efron scale values with a Spearman’s correlation coefficient of 0.701 on a set of not previously used samples. Conclusions: The robustness of our pipeline confirms its possible usage in a clinical practice as a viable decision support system for the ophthalmologists.

Botulinum toxin for temporary corneal protection after surgery for vestibular schwannoma

2011 ◽  
Vol 114 (2) ◽  
pp. 426-431 ◽  
Author(s):  
Julian Prell ◽  
Stefan Rampp ◽  
Jens Rachinger ◽  
Christian Scheller ◽  
Alex Alfieri ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Facial Nerve ◽  
Vestibular Schwannoma ◽  
Early Postoperative Period ◽  
High Grade ◽  
Ocular Complications ◽  
Levator Palpebrae ◽  
Nerve Paresis ◽  
Eye Closure ◽  
Conjunctival Redness

Object High-grade postoperative facial nerve paresis after surgery for vestibular schwannoma with insufficient eye closure involves a risk for severe ocular complications. When conservative measurements are not sufficient, conventional invasive treatments include tarsorrhaphy and eyelid loading. In this study, injection of botulinum toxin into the levator palpebrae muscle was investigated as an alternative for temporary iatrogenic eye closure. Methods Injection of botulinum toxin was indicated by an interdisciplinary decision (neurosurgery and ophthalmology) in patients with a postoperative facial nerve paresis corresponding to a House-Brackmann Grade of IV or greater and documented abnormalities concerning corneal status such as keratopathia or conjunctival redness. Twenty-five IUs of botulinum toxin were injected transcutaneously and transconjunctivally. Results Six of 11 patients with high-grade paresis showed abnormal corneal findings in the early postoperative period. In 4 of these patients, botulinum toxin was injected; 1 patient declined the treatment, and in 1 patient it was not performed because of contralateral blindness. Temporary eye closure was achieved for 2 to 6 months in all cases. In all cases, facial nerve function had recovered sufficiently in terms of eye closure when the effect of botulinum toxin subsided. Conclusion The application of botulinum toxin for temporary iatrogenic eye closure is an excellent low-risk and temporary alternative to other invasive measures for the treatment of postoperative high-grade facial nerve paresis when the facial nerve is anatomically intact.

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