scholarly journals Rapid Cataract Progression after Nd:YAG Vitreolysis for Vitreous Floaters: A Case Report and Literature Review

2017 ◽  
Vol 8 (2) ◽  
pp. 321-325 ◽  
Author(s):  
I-Ting Sun ◽  
Tsung-Han Lee ◽  
Chih-Hsin Chen
Keyword(s):  
Case Report ◽  
Crystalline Lens ◽  
Acute Onset ◽  
Blurred Vision ◽  
Complicated Cataract ◽  
Vitreous Floaters ◽  
Vitreous Loss ◽  
Pars Plana ◽  
Capsular Rupture

Purpose: We report a case of rapid cataract progression after Nd:YAG vitreolysis for vitreous floaters. Case Report: A 55-year-old man presented with acute onset of blurred vision following Nd:YAG vitreolysis for symptomatic floaters in the left eye. His initial best corrected visual acuity (BCVA) was 20/1,000 in the left eye. Ocular examinations showed frost-like opacities of the lens and a suspected break of the posterior capsule in the left eye. There were no detectable retinal lesions. Cataract surgery was then arranged. Posterior capsular rupture and vitreous loss occurred during surgery, which required a subsequent pars plana vitrectomy. After the surgery, BCVA in the left eye gradually improved to 20/20 and was maintained during a 1-year follow-up period. Conclusion: Crystalline lens injuries and rapid cataract progression may occur following Nd:YAG vitreolysis. While dealing with this type of complicated cataract, clinicians should be aware of the possibility of posterior lens capsule rupture during surgery and the need for combined vitrectomy.

scholarly journals Alport Syndrome: The Eye as a Window to the Human Body

2021 ◽  
Vol 33 (3) ◽  
pp. 46-48
Author(s):  
Aysha Tareq Nusef ◽  
Abdulla Almoosa ◽  
Wael Wagih Aly
Keyword(s):  
Hearing Loss ◽  
Case Report ◽  
Renal Insufficiency ◽  
Sensorineural Hearing Loss ◽  
Alport Syndrome ◽  
Crystalline Lens ◽  
Secondary Hypertension ◽  
Sensorineural Hearing ◽  
Blurred Vision ◽  
Ophthalmic Manifestations

Alport syndrome (AS) is a rare genetic disease affecting type four collagen production, causing renal, auditory, and ophthalmic manifestations. This case report is about a 32-year-old male who was a known case of renal insufficiency and secondary hypertension and was referred to the ophthalmology department due to blurred vision. Based on the patient‘s history and ophthalmological findings, AS was diagnosed. Ophthalmic examination showed anterior lenticonus associated with sensorineural hearing loss (SNHL) and impaired renal function. This clinical case report sheds light on the role of ophthalmology in diagnosing AS. Keywords: Collagen, Crystalline lens, Hereditary nephritis, Ophthalmology, Renal insufficiency, Sensorineural hearing loss

Drug eruption due to bupropion, a case report

2016 ◽  
Vol 33 (S1) ◽  
pp. S619-S620 ◽  
Author(s):  
N. Salgado ◽  
S. Benavente ◽  
J.M. Coll ◽  
A. Vives
Keyword(s):  
Case Report ◽  
Food Additives ◽  
Skin Lesions ◽  
Acute Onset ◽  
Diagnostic Features ◽  
Inflammatory Drugs ◽  
Competing Interest ◽  
Antidepressive Medication ◽  
Diagnostic Criterion

IntroductionWe present a clinical case of eruption caused by the use of bupropion. Bupropion is known to cause hypersensitivity reactions.Case reportWe report the case of a 48-year-old female who was diagnosed of depressive disorder. She went to emergency because a few days after prescribing bupropion (150 mg/24 h) scaly skin eruptions were found distributed along the skin. In the present case, after its introduction, bupropion was found to be a probable etiological agent. The patient was successfully treated with corticosteroids. Because of that, bupropion dosage was stopped and replaced with fluoxetine. No remissions and exacerbations were noticed in a month's follow up.DiscussionIn this case report, we present a patient with an eruption related to bupropion. The aetiological spectrum of eruption include drugs, infectious agents and food additives. Drugs attributing eruption include nonsteroidal anti-inflammatory drugs, antibiotics, and anti-epileptic drugs, antidepressive medication amongst others.ConclusionsNo specific diagnostic criterion exists for eruption and the diagnosis is purely based on clinical presentation. Diagnostic features, which suggest eruption, are the acute onset (or recurrent nature) and skin lesions.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Inverted ILM Flap Technique in a Pediatric Traumatic Macular Hole—A Case Report

2017 ◽  
Vol 1 (5) ◽  
pp. 338-340 ◽  
Author(s):  
Tommaso Nuzzo ◽  
Fabio Patelli ◽  
Giovanni Esposito ◽  
Leonardo Colombo ◽  
Luca Rossetti
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Macular Hole ◽  
Pediatric Patient ◽  
Pars Plana Vitrectomy ◽  
Flap Technique ◽  
Initial Visual Acuity ◽  
Counting Finger ◽  
Pars Plana

Purpose: To report and describe the clinical course of a pediatric traumatic macular hole (TMH) case and its management. Case Report: A pediatric patient presented a macular hole following blunt ocular trauma. The patient was followed every 2 weeks for 4 months. After the worsening of the macular hole reported by optical coherence tomography (OCT), pars plana vitrectomy with inverted flap technique plus SF6 gas tamponade was performed. Traumatic macular hole appeared closed at the OCT during follow-up. Initial visual acuity was counting finger at 30 cm. After surgery, the patient achieved a visual acuity of 20/100 at 3-month follow-up. Conclusion: This case shows a good anatomic and functional success performing a pars plana vitrectomy with inverted flap technique in a large TMH in a pediatric patient. We underline the importance of the surgical timing in the management of similar cases.

scholarly journals Modified Flapless and Sutureless Technique of Scleral Fixation of Intraocular Lens in the Management of Dislocation of Crystalline Lens Following Closed Globe Injury

2021 ◽  
Author(s):  
Naresh Babu Kannan ◽  
Sagnik Sen ◽  
Gauri Khare ◽  
Obuli Ramachandran ◽  
Kim Ramasamy
Keyword(s):  
Intraocular Lens ◽  
Demographic Data ◽  
Crystalline Lens ◽  
Modified Technique ◽  
Prospective Longitudinal Study ◽  
Scleral Fixation ◽  
Sutureless Technique ◽  
Pars Plana ◽  
Prospective Longitudinal

Abstract Purpose To evaluate the outcomes of management of subluxation of lens following closed globe injury with a modified technique of scleral fixation of intraocular lens (SFIOL). Methods This prospective longitudinal study evaluated eyes with subluxation of crystalline lens which underwent combined pars plana vitrectomy (PPV), lensectomy (PPL) along with a sutureless and flapless technique of SFIOL implantation. We documented clinico-demographic data of all eyes at baseline and final anatomical and visual outcomes at 6 months after the surgery. Results We evaluated 113 eyes of 113 subjects with a mean age of 51.5 +- 15.7 years. 48.7% of eyes had a partial subluxation of lens from patellar fossa, while 51.3% of eyes had complete subluxation. After 6 months, the baseline visual acuity of 1.40 +- 0.66 logMAR (Snellen equivalent = 6/180) increased to 0.23 +- 0.27 (Snellen equivalent = 6/9) (p < 0.001). Eyes having VA < 6/36 reduced from 79.6% at baseline to 4.4% at final follow-up (p < 0.001). Eyes having VA > = 6/12 increased from 8.8–85.8% (p < 0.001). The proportion of eyes having raised intraocular pressure reduced from 20.4–1.8% at final follow-up (p < 0.001). The most common cause of subnormal visual gain was macular degeneration secondary to commotio retinae. Conclusion Subluxation of lens is a common entity faced by ophthalmologists across the world. Lensectomy with PPV and SFIOL is an effective method of refractive rehabilitation for subluxation eyes following closed globe injury. Visual prognosis may still depend upon the initial insult on the retina.

TMOD-20. CASE REPORT: THE ODYSSEY TO THE RIGHT DIAGNOSIS. SURPRISING GLIOBLASTOMA MIMICS

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi219-vi220
Author(s):  
Patrick Dorin ◽  
Wolfgang Jochum ◽  
Arno Lauber ◽  
Marian Christoph Neidert ◽  
Thomas Hundsberger
Keyword(s):  
Limbic Encephalitis ◽  
Brain Mri ◽  
Brain Biopsy ◽  
Immunoglobulin Therapy ◽  
Tumor Stage ◽  
Acute Onset ◽  
Blurred Vision ◽  
Intravenous Immunoglobulin Therapy ◽  
Autoimmune Limbic Encephalitis

Abstract A 57-year-old female presented at the emergency room with acute onset aphasia but unremarkable cCT (incl. angiography and perfusion). Suspecting an ischemic stroke, she received thrombolysis with quick recovery of aphasia. Afterwards, myoclonic jerks of the face and right arm occurred leading to anticonvulsant therapy. Follow-up cMRI surprisingly demonstrated swollen T2w-hyperintense and Gd-enhancing left limbic, temporal and frontal lobes. Suspected herpes-simplex-encephalitis was treated with aciclovir despite unremarkable CSF results (no pleocytosis, no BBB disruption, negative HSV-PCR) on day 2 and follow-up (day 5). Due to persisting cognitive deficits, autoimmune limbic encephalitis was suspected, and intravenous immunoglobulin therapy was added. Three weeks later, she experienced new neurological symptoms (weakness, blurred vision, vomiting, headache). Follow-up brain MRI demonstrated a massive increase of multifocal Gd-enhancing lesions. Partial resection revealed the diagnosis of an IDH-wildtype glioblastoma (GB). Next generation oncogene panel testing demonstrated a GOPC-ROS1 fusion which is rarely found in GB. Due to the gliomatosis-like infiltration of both hemispheres, radiotherapy was deemed to be too toxic. Instead, she received two cycles of lomustine in absence of a MGMT-promotor methylation. Two months later cMRI showed a symptomatic second multilocular progression. 2nd-line therapy with a ROS-inhibitor was rejected, whereupon she died five weeks later. Our case is in several aspects peculiar: It demonstrates that rare GB-mimics (i.e. HSV- and autoimmune limbic encephalitis) can only be ruled out in a fast manner by brain biopsy. Watchful waiting may neglect fast progression of GB leading to the inability to provide optimal treatment (i.e. radiotherapy). Thrombolysis is strictly contraindicated in primary brain tumors, but was unharmful in our case most probably to the early tumor stage without relevant neoangiogenesis. Rare genetic abnormalities like ROS1-fusions which are reported mostly in childhood glioblastoma may be present and serve as a therapeutic target also in adult GB.

Scleral Fixation of Posterior Chamber Intraocular Lenses Using Gore-Tex Suture: Clinical Outcomes From a Single Institution

2018 ◽  
Vol 2 (5) ◽  
pp. 276-281 ◽  
Author(s):  
Benjamin Botsford ◽  
Andrew M. Williams ◽  
Ian P. Conner ◽  
Andrew W. Eller ◽  
Joseph N. Martel
Keyword(s):  
Postoperative Complications ◽  
Clinical Outcomes ◽  
Vitreous Hemorrhage ◽  
Retrospective Chart Review ◽  
Crystalline Lens ◽  
Intraocular Lenses ◽  
Posterior Chamber ◽  
Scleral Fixation ◽  
Pars Plana

Purpose: The purpose of this article is to examine the clinical outcomes of scleral fixation of intraocular lenses (IOLs) using Gore-Tex suture at our institution. Methods: A retrospective chart review was conducted of patients who underwent scleral fixation of an IOL with Gore-Tex suture with concurrent pars plana vitrectomy. Intraoperative and postoperative complications were assessed. Results: Seventy-four eyes of 74 patients were included with a mean follow-up interval of 210 days (range, 33–720 days). The mean best-corrected visual acuity improved from 20/480 (1.38 logarithm of the minimum angle of resolution [logMAR]) preoperatively to 20/78 (0.59 logMAR) postoperatively ( P < .001). Indications included dislocated lens implant (42), aphakia without capsular support (18), and subluxation of crystalline lens (14). Bausch and Lomb Akreos AO60 IOL was implanted in 52 eyes, Alcon CZ70BD in 15, and Bausch and Lomb enVista MX60 in 6. Postoperative complications included temporary ocular hypertension in 9 eyes (12%), temporary hypotony in 7 (9%), cystoid macular edema in 3 eyes (4%), corneal decompensation in 2 eyes (3%), IOL dislocation requiring exchange in 1 case (1.4%), vitreous hemorrhage in 2 cases (3%), and retinal detachment in 2 cases (3%). There were no cases of postoperative suture breakage or erosion, endophthalmitis, or hyphema. Conclusions: The use of Gore-Tex suture in scleral fixation of posterior chamber IOLs was well tolerated at a mean follow-up interval of 210 days. There were no suture-related complications.

scholarly journals Spontaneous Corneal Rupture One Week after Intrastromal Ring Segment Surgery

2013 ◽  
Vol 2 (1) ◽  
pp. 43-46
Author(s):  
Cristiana Valente ◽  
Agostino Salvatore Vaiano ◽  
Giacomo De Benedetti ◽  
Rosanna Perno ◽  
Gaudioso del Monte ◽  
...  
Keyword(s):  
Case Report ◽  
Foreign Body ◽  
African Woman ◽  
Blurred Vision ◽  
Body Sensation ◽  
Intrastromal Corneal Ring ◽  
Ring Segment ◽  
Eye Examination ◽  
Corneal Rupture

ABSTRACT Purpose To report a case of spontaneous (nontraumatic) rupture of the cornea 7 days after intrastromal ring segment surgery in a patient with pellucid marginal degeneration (PMD). Methods Case report. Results A 37-year-old African woman complains blurred vision, photophobia, foreign body sensation and redness in her left eye 7 days after an uneventful implantation of a Ferrara intrastromal corneal ring segment (ICRS) for PMD. Left eye examination revealed the rupture in the thinnest point of the cornea between the limbus and the implanted lower ICRS, and the iris prolapsed through the wound. Conclusion To the best of our knowledge, this case is the first documented spontaneous rupture of the thinnest point of the cornea in a patient with PMD treated successfully with the ICRS procedure. We examined the causes of this early and dramatic evolution and emphasize the importance of a careful follow-up. How to cite this article Vaiano AS, De Benedetti G, Perno R, del Monte G, Valente C, Caramello G. Spontaneous Corneal Rupture One Week after Intrastromal Ring Segment Surgery. Int J Kerat Ect Cor Dis 2013;2(1):43-46.

Twelve-year follow up of a case of autosomal recessive bestrophinopathy with transient resolution of retinal edema in one eye

2022 ◽  
pp. 112067212110732
Author(s):  
Lidia Remolí Sargues ◽  
Clara Monferrer Adsuara ◽  
Raquel Rodríguez López ◽  
Roberto Gallego Pinazo ◽  
Javier Montero Hernández ◽  
...  
Keyword(s):  
Case Report ◽  
Fundus Autofluorescence ◽  
Anterior Segment ◽  
Subretinal Fluid ◽  
Posterior Pole ◽  
Dietary Therapy ◽  
Retinal Edema ◽  
Blurred Vision ◽  
First Case

Purpose To report 12-year follow-up of a patient with ARB. Case report A 25-year-old man presented with blurred vision in his both eyes (OU). Best-corrected visual acuity (BCVA) was 20/63 Snellen equivalent in the right eye (OD) and 20/32 Snellen equivalent in the left eye. The intraocular pressures and anterior segment examination were unrevealing in OU. Posterior segment examination revealed multiple yellowish flecks and dots in the posterior pole in OU. Optical coherence tomography (OCT) showed subretinal fluid (SRF), intraretinal hyporeflective spaces, elongated and shaggy photoreceptors and outer retinal defects. Fundus autofluorescence demonstrated mottling hyperautofluorescence and hypoautofluorescence in the posterior pole in OU. Fluorescein angiography illustrated hyperfluorescence in the posterior pole and surrounding the arcades in OU. Multifocal electroretinography objectified mild to markedly abnormal responses in all ring areas in OU. Molecular genetic testing confirmed two heterozygous sequence variations in the BEST1 gene. At 4 years of follow-up, OCT revealed a complete resolution of SRF and a partial resolution of intraretinal hyporeflective spaces in the OD with corresponding improvement in the BCVA to 20/23 Snellen equivalent in the OD, even though outer retinal defects persisted. Our patient denied recent changes in his alimentary habits and medical history at that time. Posteriorly, SRF and intraretinal hyporeflective spaces reappeared in the OD. Conclusion To the best of our knowledge, this is the first case report of ARB with a transient resolution of retinal edema in one eye without medical treatment and dietary therapy.

scholarly journals Long-Term Follow-Up Results of a Patient Undergoing Acute Retinal Necrosis: A Case Report and Literature Review

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Büşra Köse ◽  
Hidayet Erdöl ◽  
Dilek Uzlu
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Acute Retinal Necrosis ◽  
Vascular Involvement ◽  
Systemic Steroid ◽  
Fundus Fluorescein Angiography ◽  
Blurred Vision ◽  
Corrected Visual Acuity ◽  
Best Corrected Visual Acuity

Purpose. To describe the follow-up and treatment approach of a patient with acute retinal necrosis. Case Report. A 44-year-old male patient, who had complaints of pain in the right eye and blurred vision, was referred to our clinic. Best-corrected visual acuity (BCVA) was 0.4. There was 2+ anterior chamber reaction and diffuse smooth-rounded keratic precipitates. Fundus examination revealed optic nerve and vascular involvement. Fundus fluorescein angiography revealed extensive ischemia in the periphery. Oral antiviral therapy was preferred. In addition, systemic steroid and laser photocoagulation were applied. Nonetheless, retinal detachment developed 2 months later. Detachment, silicon removal, and cataract surgery were performed sequentially. It was observed that the patient was followed for 4.5 years and did not have contralateral eye involvement. Best-corrected visual acuity remained stable at 0.3. Conclusion. Early diagnosis, appropriate treatment, accurate complication management, and frequent follow-up may provide useful vision in patients with acute retinal necrosis.

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