Using Controlled Substance Receipt Patterns to Predict Prescription Overdose Death

Pharmacology ◽  
2017 ◽  
Vol 101 (3-4) ◽  
pp. 140-147 ◽  
Author(s):  
Christina T. Holt ◽  
Kenneth L. McCall ◽  
Gary Cattabriga ◽  
Chunhao Tu ◽  
Elenna K. Smalley ◽  
...  
Keyword(s):  
Drug Overdose ◽  
Monitoring Program ◽  
Overdose Death ◽  
Prescription Monitoring ◽  
Prescribing Trends ◽  
Complete State ◽  
Controlled Substance ◽  
Overdose Deaths ◽  
Morphine Equivalent ◽  
Drug Overdose Death

Background: This study evaluates complete state data from controlled substance prescribing trends in the prescription monitoring program (PMP) database and their association with the risk of prescription drug overdose death. Summary: Maine PMP records of individuals who died of prescription overdose deaths between 2006 and 2010 were selected (n = 690). For each subject, an age, gender, and residence matched cohort of PMP users in a 50: 1 ratio was identified (n = 34,500). Key Messages: Prescription opioids contributed to 480 of 690 prescription deaths, many co-ingestions were noted, and OR for overdose death increased with milligram of morphine equivalent (MME)/day >100. The majority who were prescribed MME >100 per day received a prescription within 90 days of overdose matching the toxicology cause of death. Conclusions: Medication profiles available through state PMP can identify dosing of prescriptions associated with drug overdose death.

The influence of living along the U.S.-Mexico border on unintentional drug overdose death, New Mexico (USA), 2005–2009

2012 ◽  
Vol 125 (1-2) ◽  
pp. 19-26 ◽  
Author(s):  
Nina G. Shah ◽  
Sarah L. Lathrop ◽  
Janet E. Flores ◽  
Michael G. Landen
Keyword(s):  
New Mexico ◽  
Drug Overdose ◽  
Overdose Death ◽  
Mexico Border ◽  
The U.S ◽  
Drug Overdose Death

scholarly journals A History of Being Prescribed Controlled Substances and Risk of Drug Overdose Death

Pain Medicine ◽  
2012 ◽  
Vol 13 (1) ◽  
pp. 87-95 ◽  
Author(s):  
Leonard J. Paulozzi ◽  
Edwin M. Kilbourne ◽  
Nina G. Shah ◽  
Kurt B. Nolte ◽  
Hema A. Desai ◽  
...  
Keyword(s):  
Drug Overdose ◽  
Overdose Death ◽  
Controlled Substances ◽  
History Of ◽  
Drug Overdose Death

scholarly journals Emergency department utilization and subsequent prescription drug overdose death

2015 ◽  
Vol 25 (8) ◽  
pp. 613-619.e2 ◽  
Author(s):  
Joanne E. Brady ◽  
Charles J. DiMaggio ◽  
Katherine M. Keyes ◽  
John J. Doyle ◽  
Lynne D. Richardson ◽  
...  
Keyword(s):  
Emergency Department ◽  
Prescription Drug ◽  
Drug Overdose ◽  
Emergency Department Utilization ◽  
Overdose Death ◽  
Drug Overdose Death

scholarly journals Urban–Rural Differences in Drug Overdose Death Rates, 1999–2019

2021 ◽  
Author(s):  
Holly Hedegaard
Keyword(s):  
Drug Overdose ◽  
Vital Statistics ◽  
Mortality Data ◽  
Death Rates ◽  
Overdose Death ◽  
Urban Rural ◽  
Drug Overdose Death

This report uses the most recent mortality data from the National Vital Statistics System (NVSS) to examine urban–rural differences in drug overdose death rates, for all drugs and by selected types of opioids and stimulants.

scholarly journals Who is Overdosing? An Updated Picture of Overdose Deaths From 2008 to 2015

2017 ◽  
Vol 4 ◽  
pp. 233339281772742 ◽  
Author(s):  
Gregory Eigner ◽  
Brian Henriksen ◽  
Philip Huynh ◽  
David Murphy ◽  
Christopher Brubaker ◽  
...  
Keyword(s):  
Cause Of Death ◽  
Drug Overdose ◽  
Monitoring Program ◽  
Place Of Residence ◽  
Department Of Health ◽  
Common Drug ◽  
Drug Classes ◽  
Allen County ◽  
Overdose Deaths

Purpose: To determine the role of opioids in drug overdose deaths in Allen County, Indiana between January 1, 2008, and December 31, 2015. Methods: File review of 418 overdose deaths was performed using Indiana State Department of Health death certificates available through the Allen County Coroner’s Office. Data from autopsy and toxicology reports and coroner-requested prescribing data from Indiana’s Prescription Monitoring Program were reviewed. Cause of death and available data were analyzed to identify patterns and trends related to overdose deaths. Results: Four hundred eighteen drug overdose deaths were identified (336 accidental, 66 intentional, and 16 undetermined). Mean age was 42.5 years, 88.5% were Caucasian, and 68.7% were employed. The majority of deaths occurred at a place of residence (71.4%) and with other people present (57.5% of the time). Depression was the most common comorbidity identified. The most common drug classes identified by toxicology were opioids, followed by benzodiazepines. Significant increases in both heroin (35% of deaths in 2015 versus 8.2% in 2013) and fentanyl (30% of deaths in 2015 versus 2.2% in 2011) were observed. Conclusions: Drug overdose continues to be a significant cause of death in Allen County. The majority of deaths were accidental and in relatively young, employed individuals. Prevention and awareness strategies should be encouraged, given that the majority of overdose deaths occurred at a place of residence with other people frequently present. Additional concerns about patterns of drug use were confirmed with marked increases in both heroin and fentanyl contributing to overdose deaths in the latter part of the study.

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