scholarly journals Endoscopic Full-Thickness Resection of a Colonic Lateral Spreading Tumor

2018 ◽  
Vol 36 (3) ◽  
pp. 252-256 ◽  
Author(s):  
Ana-Maria Bucalau ◽  
Arnaud Lemmers ◽  
Marianna Arvanitakis ◽  
Daniel Blero ◽  
Horst Neuhaus

The Full-Thickness Resection Device (FTRD; Ovesco Endoscopy, Tübingen, Germany) combines endoscopic full-thickness resection (EFTR) of gastrointestinal lesions with closure and cutting of the tissue in one integrated procedure. It provides en-bloc resection with an integral wall specimen for histopathological evaluation. This resection technique is partially filling of the gaps between the current procedures of choice in endoscopy (endoscopic mucosal resection and endoscopic submucosal dissection) and surgery. We present the case of an EFTR procedure performed for a periappendicular lateral spreading tumor.

Endoscopy ◽  
2020 ◽  
Vol 52 (11) ◽  
pp. 1014-1023 ◽  
Author(s):  
Liselotte W. Zwager ◽  
Barbara A. J. Bastiaansen ◽  
Maxime E. S. Bronzwaer ◽  
Bas W. van der Spek ◽  
G. Dimitri N. Heine ◽  
...  

Abstract Background Endoscopic full-thickness resection (eFTR) is a minimally invasive resection technique that allows definite diagnosis and treatment for complex colorectal lesions ≤ 30 mm unsuitable for conventional endoscopic resection. This study reports clinical outcomes from the Dutch colorectal eFTR registry. Methods Consecutive patients undergoing eFTR in 20 hospitals were prospectively included. The primary outcome was technical success, defined as macroscopic complete en bloc resection. Secondary outcomes were: clinical success, defined as tumor-free resection margins (R0 resection); full-thickness resection rate; and adverse events. Results Between July 2015 and October 2018, 367 procedures were included. Indications were difficult polyps (non-lifting sign and/or difficult location; n = 133), primary resection of suspected T1 colorectal cancer (CRC; n = 71), re-resection after incomplete resection of T1 CRC (n = 150), and subepithelial tumors (n = 13). Technical success was achieved in 308 procedures (83.9 %). In 21 procedures (5.7 %), eFTR was not performed because the lesion could not be reached or retracted into the cap. In the remaining 346 procedures, R0 resection was achieved in 285 (82.4 %) and full-thickness resection in 288 (83.2 %). The median diameter of resected specimens was 23 mm. Overall adverse event rate was 9.3 % (n = 34/367): 10 patients (2.7 %) required emergency surgery for five delayed and two immediate perforations and three cases of appendicitis. Conclusion eFTR is an effective and relatively safe en bloc resection technique for complex colorectal lesions with the potential to avoid surgery. Further studies assessing the role of eFTR in early CRC treatment with long-term outcomes are needed.


2020 ◽  
Vol 21 ◽  
Author(s):  
Giovanni Oliviero ◽  
Mario Gagliardi ◽  
Marco Napoli ◽  
Orazio Labianca ◽  
Antonio D\'Antonio ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Goro Shibukawa ◽  
Atsushi Irisawa ◽  
Ai Sato ◽  
Yoko Abe ◽  
Akane Yamabe ◽  
...  

Objectives. Recently, opportunities to encounter superficial nonampullary duodenal epithelial tumor (SNADET) have increased. EMR and ESD are performed to treat SNADET. However, the rate of perforation is higher than that of other gastrointestinal lesions, regardless of which method is used. Underwater EMR (UW-EMR) is immersion treatment of SNADET, which has low risk of perforation and can remove lesions safely and completely. In the present study, we retrospectively investigated patients in whom UW-EMR was performed to evaluate the feasibility and safety of UW-EMR for the treatment of SNADET. Methods. The primary endpoint was to evaluate the feasibility of UW-EMR for the treatment of SNADET, and secondary objective was to determine the operation’s safety. Results. There were 14 participants, with a total of 16 lesions, who underwent UW-EMR between August 2015 and December 2017. Histological heteromorphism revealed that seven patients had low-grade adenoma, seven had high-grade adenoma, and two had adenocarcinoma. En bloc resection was performed in 14 lesions. In two patients, nodular lesions were observed in the scar and biopsy confirmed recurrences. There were no serious adverse events including bleeding or perforation. Conclusions. UW-EMR may be a safe and effective treatment method for SNADET, if its therapeutic indication is adequately considered.


2008 ◽  
Vol 65 (2) ◽  
pp. 175-177
Author(s):  
Vojkan Stanic ◽  
Tatjana Vulovic ◽  
Davor Stamenovic ◽  
Gordana Djordjevic

Background. Sternal benign neoplasms are extremely rare. Chondroma is a benign tumor of cartilage and can be single or multiple. Case report. We presented a case of 28-year-old woman with chondroma of the sternum treated by "en bloc" resection of the tumor (subtotal sternectomy). The chest wall defect was repaired by the placement of Marlex mesh and metylmethacrylate ("sandwich method") for stabilization of the thoracic wall. This place was covered with pectoralis major muscle and skin. The postoperative course was uneventful and the wounds healed by primary intention. Conclusion. The functional and cosmetic results in the usage of Marlex mesh with metylmethacrylate to repair a large full-thickness defect after subtotal sternectomy caused by chondroma were good and the patient was able to resume her preoperative level of activity.


Endoscopy ◽  
2018 ◽  
Vol 50 (10) ◽  
pp. E296-E298 ◽  
Author(s):  
Alexandru Lupu ◽  
Jérémie Jacques ◽  
Jérôme Rivory ◽  
Jean-Christophe Saurin ◽  
Florian Rostain ◽  
...  

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