scholarly journals Multimodal Imaging and Histopathological Evaluation of Berger’s Space

2019 ◽  
Vol 6 (1) ◽  
pp. 3-9
Author(s):  
Virginia Mares ◽  
Marcio B. Nehemy ◽  
Diva R. Salomão ◽  
Shannon Goddard ◽  
Jaime Tesmer ◽  
...  
Keyword(s):  
Multimodal Imaging ◽  
Histological Study ◽  
Anterior Segment ◽  
Vitreous Hemorrhage ◽  
Slit Lamp ◽  
Anterior Segment Oct ◽  
Pathological Conditions ◽  
Actual Space ◽  
In Vivo Analysis

Objective: To demonstrate the multimodal imaging and histopathology of Berger’s space. Methods: We conducted a retrospective in vivo analysis of 4 patients demonstrating Berger’s space with intraocular pathological conditions, documented by slit-lamp biomicroscopic photography and, in 2 patients, also by optical coherence tomography (OCT). Additionally, we carried out a retrospective histological study of 7 enucleated eyes with retinoblastoma demonstrating Berger’s space. A review of the literature was also performed. Results: Two eyes had slit-lamp photographs. One case showed Berger’s space surrounded by vitreous hemorrhage. In the other case, amyloid was trapped within Berger’s space. In another 2 eyes that were pseudophakic, Berger’s space was visible on anterior segment OCT. One had amyloid trapped in Berger’s space that could be seen with OCT. The histological review of the 7 enucleated eyes with advanced retinoblastoma demonstrated the presence of pyknotic cells in Berger’s space. Conclusions: Berger’s space is an actual space in pathological conditions and can be an important site of pathology. Additionally, to our knowledge, this is the first time that Berger’s space has been documented by anterior segment OCT in a clinical setting.

In vivo analysis and comparison of anterior segment structures of both eyes in unilateral Fuchs’ uveitis syndrome

2019 ◽  
Vol 257 (7) ◽  
pp. 1489-1498 ◽  
Author(s):  
Muhammet Derda Ozer ◽  
Fatih Kebapci ◽  
Muhammed Batur ◽  
Erbil Seven ◽  
Serek Tekin
Keyword(s):  
Anterior Segment ◽  
In Vivo Analysis ◽  
Fuchs Uveitis Syndrome

scholarly journals In-vivo anterior segment OCT imaging provides unique insight into cerulean blue-dot opacities and cataracts in Down syndrome

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Julie-Anne Little ◽  
Aman-Deep S. Mahil ◽  
Patrick Richardson ◽  
J. Margaret Woodhouse ◽  
Valldeflors Vinuela-Navarro ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Anterior Segment ◽  
Anterior Segment Oct ◽  
Oct Imaging ◽  
Insight Into

scholarly journals Pre-Descemetic Placement of Intracorneal Ring Segments for Keratoconus after Mechanical Implantation

2021 ◽  
pp. 940-943
Author(s):  
Faady Yahya ◽  
Christian F. Prünte ◽  
Hendrik P.N. Scholl ◽  
Zisis Gatzioufas
Keyword(s):  
Visual Acuity ◽  
High Resolution ◽  
Femtosecond Laser ◽  
Anterior Segment ◽  
Slit Lamp ◽  
Anterior Segment Oct ◽  
Ring Segment ◽  
Intracorneal Ring Segment

We report the case of a 23-year-old male who was referred to our clinic for a routine follow-up examination. The patient was treated for keratoconus 3 years ago in Colombia, where intracorneal ring segments were implanted mechanically in both eyes to improve his visual acuity. Surprisingly, we discovered a pre-descemetic placement of intracorneal ring segments, which could lead to potential complications, under circumstances. We illustrate this impressive finding with slit-lamp photography and high-resolution anterior segment OCT and advocate for the use of femtosecond laser as the method of choice for intracorneal ring segment insertion in order to provide maximal precision and safety.

scholarly journals Anterior Segment Examination with Slit-Lamp Biomicroscope: What Should be Highlighted?

2021 ◽  
Vol 3 (5) ◽  
pp. 14-19
Author(s):  
Fazella Kirara Sakti
Keyword(s):  
Pathological Condition ◽  
Anterior Part ◽  
Anterior Segment ◽  
Health Assessment ◽  
Slit Lamp ◽  
Pathological Conditions ◽  
Ocular Disorders ◽  
Eye Examination ◽  
Illumination Source ◽  
Ocular Health

Ocular health assessment consists of various types of examinations that aim to find pathological conditions in the eye so that it helps ophthalmologists to diagnose and provide therapy for ocular disorders suffered by the patients. Slit-lamp biomicroscope is one of the most important eye assessments and has become the standard in assessing the pathological condition of the anterior part of the eye. This examination is performed using a stereoscopic biomicroscope instrument in combination with a bright illumination source. The results of the anterior segment examination using slit-lamp biomicroscope may provide more detailed ocular findings, such as the abnormalities of the eyelid, conjunctival lesions, abnormalities of the cornea, lens, or other parts of the anterior ocular segments. Therefore, the ability to examine slit-lamp biomicroscope is essential for the ophthalmologist. This review will discuss the eye examination using slit-lamp biomicroscope and the findings that will make it easier for clinicians to determine the direction of diagnostic approach in ocular patients. 

Contact lens induced bacterial keratitis in LCD II: Management and multimodal imaging: a case report and review of literature

2020 ◽  
pp. 112067212096872
Author(s):  
Munirah Alafaleq ◽  
Juliette Knoeri ◽  
Sandrine Boutboul ◽  
Vincent Borderie
Keyword(s):  
Contact Lens ◽  
Multimodal Imaging ◽  
Anterior Segment ◽  
Corneal Dystrophy ◽  
Bacterial Keratitis ◽  
Infectious Keratitis ◽  
Bandage Contact Lens ◽  
Lattice Corneal Dystrophy ◽  
Subepithelial Fibrosis

Purpose: To describe the management and multimodal imaging of lattice corneal dystrophy type II (LCD-II) complicated by an infectious keratitis due to a bandage contact lens and to review current literature. Observation: A 50-year-old female was diagnosed with Meretoja’s Syndrome by the triad of facial palsy, loose skin (cutix laxa), and stromal corneal dystrophy. At slit lamp, bilateral lattice corneal dystrophy (LCD) was characterized by multiple linear refractile lines and subepithelial fibrosis along with Neurotrophic keratitis Mackie grade I. Findings of anterior segment optical coherence tomography (AS-OCT) were epithelial irregularity, subepithelial fibrosis, hyperreflectivity on anterior stromal layer, lobulated stromal surface. In vivo confocal microscopy (IVCM) showed hyperreflected deposits on the basal and Bowman layers, visible keratocytes; fine lines and streaks between corneal lamella. The sub-basal nerve plexus and the stromal nerves were no longer visible. She presented in emergency with a left red eye. A severe bacterial keratitis was diagnosed as a complication of a bandage contact lens used to treat recurrent epithelial erosion. Corneal anesthesia was complete. Corneal neovascularization was evident 10 weeks later and topical bevacizumab (5 mg/ml) was introduced twice daily. Partial regression of deep stromal vessels was noticed at 3 months. Conclusion: In Meretoja’s syndrome, neurotrophic keratopathy secondary to polyneuropathy due to systemic amyloid deposits is present in the advanced stages, promotes recurrent corneal erosions. Corneal sensitivity test, AS-OCT and IVCM are crucial in the diagnosis behind any recurrent corneal erosion. The use of bandage contact lens should be avoided in Meretoja’s syndrome to prevent a possible infectious keratitis.

scholarly journals Anterior Segment Imaging in Combat Ocular Trauma

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Denise S. Ryan ◽  
Rose K. Sia ◽  
Marcus Colyer ◽  
Richard D. Stutzman ◽  
Keith J. Wroblewski ◽  
...  
Keyword(s):  
Ocular Trauma ◽  
Anterior Segment ◽  
Case Series ◽  
Ocular Injury ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
Ocular Imaging ◽  
Ocular Injuries ◽  
Anterior Segment Imaging

Purpose. To evaluate the use of ocular imaging to enhance management and diagnosis of war-related anterior segment ocular injuries.Methods. This study was a prospective observational case series from an ongoing IRB-approved combat ocular trauma tracking study. Subjects with anterior segment ocular injury were imaged, when possible, using anterior segment optical coherence tomography (AS-OCT), confocal microscopy (CM), and slit lamp biomicroscopy.Results. Images captured from participants with combat ocular trauma on different systems provided comprehensive and alternate views of anterior segment injury to investigators.Conclusion. In combat-related trauma of the anterior segment, adjunct image acquisition enhances slit lamp examination and enables real timeIn vivoobservation of the cornea facilitating injury characterization, progression, and management.

scholarly journals A rare presentation of exudative macroaneurysms in unilateral Eales’ disease

2017 ◽  
Vol 9 (1) ◽  
pp. 95-98 ◽  
Author(s):  
M Nada ◽  
S Qanoongo ◽  
SV Singh ◽  
AK Khurana
Keyword(s):  
Anterior Segment ◽  
Vitreous Hemorrhage ◽  
Fundus Examination ◽  
Slit Lamp ◽  
Rare Presentation ◽  
Normal Limits ◽  
Eales Disease ◽  
Bilateral Condition ◽  
Laboratory Investigations

Background: A case of exudative macroaneurysms in unilateral Eales’ disease is reported. ‘Eales disease’ is an idiopathic bilateral occlusive periphlebitis with neovascularisation and mostly presents with vitreous hemorrhage. Case: A 30 year old male presented with diminution of vision in left eye (6/36) for 1 month. Slit Lamp examination of both eyes revealed normal anterior segment. Fundus examination of left eye with + 90 D lens revealed reddish lesions at the macula with surrounding circinate exudation. On peripheral examination hemorrhages were seen along with vasculitis in the superotemporal quadrant.The right eye fundus was normal.All laboratory investigations were found within normal limits. Conclusion: Eales’ disease is mostly a bilateral condition but this case is rare as there is uniocular involvement with exudative macroaneurysms.Laser therapy was instituted which was effective in management of this condition with restoration of normal visual acuity.There was no relapse on follow up for 2 years. 

scholarly journals The Value of Anterior Segment Optical Coherence Tomography in Different Types of Corneal Infections: An Update

2021 ◽  
Vol 10 (13) ◽  
pp. 2841
Author(s):  
Ahmed A. Abdelghany ◽  
Francesco D’Oria ◽  
Jorge Alio Del Barrio ◽  
Jorge L. Alio
Keyword(s):  
Optical Coherence Tomography ◽  
Imaging Modality ◽  
Wide Spectrum ◽  
Anterior Segment ◽  
Corneal Edema ◽  
Response To Treatment ◽  
Optical Coherence ◽  
Slit Lamp ◽  
Cross Sectional

Anterior segment optical coherence tomography (AS-OCT) is a modality that uses low-coherence interferometry to visualize and assess anterior segment ocular features, offering several advantages of being a sterile and noncontact modality that generates high-resolution cross-sectional images of the tissues. The qualitative and quantitative information provided by AS-OCT may be extremely useful for the clinician in the assessment of a wide spectrum of corneal infections, guiding in the management and follow-up of these patients. In clinical practice, infections are routinely evaluated with slit-lamp biomicroscopy, an examination and imaging modality that is limited by the physical characteristics of light. As a consequence, the depth of pathology and the eventually associated corneal edema cannot be accurately measured with the slit-lamp. Therefore, it represents a limit for the clinician, as in vivo information about corneal diseases and the response to treatment is limited. Resolution of corneal infection is characterized by an early reduction in corneal edema, followed by a later reduction in infiltration: both parameters can be routinely measured with standardized serial images by AS-OCT.

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