scholarly journals Transient Angle Obstruction Detected by Anterior-Segment Optical Coherence Tomography and Intraocular Pressure Elevation after Hemodialysis

2021 ◽  
pp. 761-765
Author(s):  
Mihoko Mochiji ◽  
Aika Tsutsui ◽  
Kaoru Manabe ◽  
Masaki Tanito

An 80-year-old Japanese man presented with decreased vision in his right eye (OD) after every hemodialysis (HD) session beginning several months previously. His local ophthalmologist prescribed antiglaucoma medications because of high intraocular pressure (IOP) (38 mm Hg) OD 4 months previously; with treatment, the IOP fluctuated between 6 and 34 mm Hg OD. When hospitalized, the IOP was measured, and the anterior chamber was observed by anterior-segment optical coherence tomography (AS-OCT) before and after HD. Before HD, the IOP levels were 7 mm Hg OD and 8 mm Hg in the left eye (OS). AS-OCT showed marked anterior iris bowing due to circumferential posterior synechia OD. The scan showed irido-trabecular contact (ITC) in the nasal angle and not the temporal angle OD. Immediately after HD, the IOP levels were 28 mm Hg OD and 12 mm Hg OS; AS-OCT showed ITC in the nasal and temporal angles OD. Since the iris bombe and HD-induced increase in the ITC were expected to have caused the IOP spike and blurred vision, posterior synechialysis and goniosynechialysis were performed OD. Postoperatively, the iris plane flattened; no IOP spike was recorded, and the blurred vision after HD resolved. At 22 months postoperatively, the IOP was 7 mm Hg in both eyes (OU). No deterioration of visual acuity and visual field was recorded during the follow-up period OU. IOP spikes can occur during and after HD because of transient anterior chamber angle obstruction in cases with narrow angles. AS-OCT is useful for detecting minor morphologic changes in the anterior chamber angle during HD.

2016 ◽  
Vol 57 (2) ◽  
pp. 87-91 ◽  
Author(s):  
Jie Lan ◽  
Dapeng Sun ◽  
Khatoon Alabdulrasool ◽  
Hassan Ebrahim Yusuf ◽  
Lu Zhang

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Poemen Pui-man Chan ◽  
Gilda Lai ◽  
Vivian Chiu ◽  
Anita Chong ◽  
Marco Yu ◽  
...  

Abstract This study compared the test–retest variabilities and measurement agreement of anterior chamber angle (ACA) dimensions measured by two anterior segment swept-source optical coherence tomography (SS-OCT)—the ANTERION (Heidelberg Engineering, Heidelberg, Germany) and CASIAII (Tomey, Nagoya, Japan). Thirty-eight subjects, 18 patients with primary angle closure and 20 healthy participants with open angles, were included. The mean age was 54.7 ± 15.8 years (range: 26–75 years). One eye of each subject was randomly selected for anterior segment imaging by ANTERION and CASIAII, using the same scan pattern (6 evenly spaced radial scans across the anterior segment for three times) in the same visit. The between- and within-instrument agreement and repeatability coefficients of angle open distance (AOD500), trabecular-iris space area (TISA500), lens vault (LV), scleral spur-scleral spur distance (SSD), anterior chamber depth (ACD), and pupil diameter (PD) were measured. The anterior and posterior boundaries of the cornea, iris, and lens were automatically segmented by the SS-OCT instruments; the scleral spur was manually located by a single masked observer. There were significant differences between ANTERION and CASIAII measurements; the SSD, PD, and ACD were smaller whereas AOD500 and TISA500 were greater in ANTERION compared with CASIAII (P < 0.001). Anterior segment measurements obtained from the two SS-OCT instruments showed strong associations (R2 ranged between 0.866 and 0.998) although the between-instrument agreement was poor; the spans of 95% limits of between-instrument agreement were ≥ 1.5-folds than the within-instrument agreement for either instrument. Whereas both SS-OCT instruments showed low test–retest measurement variabilities, the repeatability coefficients of AOD500, TISA500, ACD, and PD were slightly smaller for CASIAII than ANTERION (P ≤ 0.012).


2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Yong Un Shin ◽  
Ji Hong Kim ◽  
Heeyoon Cho ◽  
Dae Sung Kim ◽  
Joo-Hark Yi ◽  
...  

Purpose. To investigate the effect of hemodialysis (HD) on the anterior chamber angle by anterior segment optical coherence tomography (ASOCT) and other ophthalmologic parameters in patients with end-stage kidney disease (ESKD). Methods. A prospective observational study was performed on 20 patients who underwent HD for ESKD. Anterior chamber angle images were obtained by 16 mm line scan of ASOCT. The angle opening distance (AOD) and the trabecular-iris space area (TISA) were determined using the ImageJ program. Additional 12 mm horizontal and 9 mm vertical wide-field scans centered on the posterior pole were performed for the measurement of peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell-inner plexiform layer (mGCIPL) thickness. Changes in intraocular pressure (IOP), AOD, TISA, pRNFL thickness, and mGCIPL thickness before and after HD were statistically analyzed. Results. The IOP decreased significantly from 17.5 ± 3.4 before HD to 16.2 ± 2.3 after HD (P=0.017). There was a statistically significant decrease in AOD 750 and TISA 750 (P=0.005 and P=0.007, respectively). AOD 500 and TISA 500 also decreased, which was almost statistically significant (P=0.061 and P=0.081, respectively). Mean pRNFL thickness and mGCIPL thickness did not show significant change after HD. Conclusion. We observed a significant decrease in IOP and anterior chamber angle measurements after HD. Our study suggests that HD can influence the anterior segment structure of eyes.


2007 ◽  
Vol 48 (8) ◽  
pp. 3683 ◽  
Author(s):  
Sunita Radhakrishnan ◽  
Jovina See ◽  
Scott D. Smith ◽  
Winifred P. Nolan ◽  
Zheng Ce ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Ricardo J. Cumba ◽  
Sunita Radhakrishnan ◽  
Nicholas P. Bell ◽  
Kundandeep S. Nagi ◽  
Alice Z. Chuang ◽  
...  

Purpose. To evaluate intraobserver and interobserver agreement in locating the scleral spur landmark (SSL) and anterior chamber angle measurements obtained using Fourier Domain Anterior Segment Optical Coherence Tomography (ASOCT) images.Methods. Two independent, masked observers (SR and AZC) identified SSLs on ASOCT images from 31 eyes with open and nonopen angles. A third independent reader, NPB, adjudicated SSL placement if identifications differed by more than 80 μm. Nine months later, SR reidentified SSLs. Intraobserver and interobserver agreement in SSL placement, trabecular-iris space area (TISA750), and angle opening distance (AOD750) were calculated.Results. In 84% of quadrants, SR’s SSL placements during 2 sessions were within 80 μm in both theX- andY-axes, and in 77% of quadrants, SR and AZC were within 80 μm in both axes. In adjudicated images, 90% of all quadrants were within 80 μm, 88% in nonopen-angle eyes, and 92% in open-angle eyes. The intraobserver and interobserver correlation coefficients (with and without adjudication) were above 0.9 for TISA750 and AOD750 for all quadrants.Conclusions. Reproducible identification of the SSL from images obtained with FD-ASOCT is possible. The ability to identify the SSL allows reproducible measurement of the anterior chamber angle using TISA750 and AOD750.


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