The Combined Use of rhBMP-2/ACS, Autogenous Bone Graft, a Bovine Bone Mineral Biomaterial, Platelet-Rich Plasma, and Guided Bone Regeneration at Nonsubmerged Implant Placement for Supracrestal Bone Augmentation. A Case Report

Because a concept of an osteointegrated dental implant system was established, prognosis of a dental implant at treatment improved and the treatment of restoration for missing teeth was changed. However, a dental implant treatment into atrophic jaw bone requires bone augmentation, obviously. At this time, we studied for the purpose of establishing the evidence of each method for clinical application of these bone augmentation method, such as guided bone regeneration (GBR), and autogenous bone block graft (BBG). In addition, we pursued the basic study of the evidence about the bone formation with platelet rich plasma (PRP) which recognized the availability in clinic. Furthermore, we present the results of basic studies which we tested for the purpose of applying a low-intensity pulse ultrasound (LIPU) irradiation applied to a fracture treatment in orthopedics area to intra-oral area, specially the condition after implant placement. In the results of comparison with GBR site and BBG, the differences of labeling bands were observed with a fluorescence microscopy. There was much labeling bands on GBR sections in comparison with BBG. This meaning that the bone remodeling around implants at GBR site was more active than BBG site. And the new bone formation by PRP was identified on soft X-ray graphically at first week after PRP applied mandible bone defect (experimental side). At same region of first week specimen, we confirmed positive reactions of platelet derived growth factor

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Autogenous Bone Graft Versus Bovine Bone Graft in Association With Platelet-Rich Plasma for the Reconstruction of Alveolar Clefts: A Pilot Study

The Cleft Palate-Craniofacial Journal ◽

10.1177/1055665618770194 ◽

2018 ◽

Vol 56 (1) ◽

pp. 134-140 ◽

Cited By ~ 3

Author(s):

Bruno Torres Bezerra ◽

John Nadson Andrade Pinho ◽

Fabrício Eneas Diniz Figueiredo ◽

José Renato Moraes Carvalho Barreto Brandão ◽

Lucas Celestino Guerzet Ayres ◽

...

Keyword(s):

Bone Graft ◽

Platelet Rich Plasma ◽

Bone Grafts ◽

Autogenous Bone ◽

Bovine Bone ◽

Alveolar Bone Grafting ◽

Significant Difference ◽

Group A ◽

Autologous Bone ◽

Group B

Objective: To compare the outcomes of 2 different bone graft materials: autogenous bone grafts from mandibular symphysis and bovine bone grafts associated with platelet-rich plasma (PRP). Methods: Twenty individuals met the inclusion criteria and accepted to participate in the study. Group A patients underwent alveolar bone grafting using autologous bone and group B patients using a bovine bone graft associated with PRP. Cone beam computed tomography scans were taken and reconstructed 3-dimensionally for all patients preoperatively and 1 year postoperatively. Results: A significant reduction was detected for area and volume within group A and group B. Between groups, no significant difference was found for area or volume. Conclusions: Bovine grafts associated with PRP are a good option for the reconstruction of alveolar clefts and provide good results such as autologous bone grafts.

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Efficacy of Guided Bone Regeneration Using Composite Bone Graft and Resorbable Collagen Membrane in Seibert's Class I Ridge Defects: Radiological Evaluation

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-10-00211 ◽

2013 ◽

Vol 39 (4) ◽

pp. 455-462 ◽

Cited By ~ 4

Author(s):

Saravanan Pushparajan ◽

Ramakrishnan Thiagarajan ◽

Ambalavanan Namasi ◽

Pamela Emmadi ◽

Harshini Saravanan

Keyword(s):

Bone Graft ◽

Bone Regeneration ◽

Guided Bone Regeneration ◽

Class I ◽

Autogenous Bone ◽

Collagen Membrane ◽

Bovine Bone ◽

Radiological Evaluation ◽

Bone Width ◽

Composite Bone

The purpose of the study was to evaluate radiologically the efficacy of guided bone regeneration using composite bone graft (autogenous bone graft and anorganic bovine bone graft [Bio-Oss]) along with resorbable collagen membrane (BioMend Extend) in the augmentation of Seibert's class I ridge defects in maxilla. Bone width was evaluated using computerized tomography at day 0 and at day 180 at 2 mm, 4 mm, and 6 mm from the crest. There was a statistically significant increase in bone width between day 0 and day 180 at 2 mm, 4 mm, and 6 mm from the crest. The results of the study demonstrated an increase in bone width of Seibert's class I ridge defects in the maxilla of the study patients.

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Implant Site Guided Bone Regeneration and Pontic Site Ridge Preservation: A Case Report

PRILOZI ◽

10.2478/prilozi-2021-0028 ◽

2021 ◽

Vol 42 (2) ◽

pp. 103-108

Author(s):

Darko Veljanovski ◽

Denis Baftijari ◽

Zoran Susak ◽

Aneta Atanasovska Stojanovska

Keyword(s):

Soft Tissue ◽

Bone Regeneration ◽

Soft Tissues ◽

Guided Bone Regeneration ◽

Autogenous Bone ◽

Collagen Membrane ◽

Ridge Preservation ◽

Bovine Bone ◽

Implant Placement ◽

Barrier Membrane

Abstract Guided bone regeneration (GBR) is a therapeutic modality to achieve bone regeneration with the use of barrier membranes. The use of deproteinized bovine bone material (DBBM) for ridge preservation allows the preservation of the edentulous ridge dimensions. Here, we present a case of horizontal GBR using DBBM and a resorbable membrane, with simultaneous implant placement. Simultaneously, ridge preservation of the pontic area, using DBBM within a “socket seal” procedure was performed. Two implants were places at sites 23 and 26 to support a fixed partial denture (FPD). The mesial implant showed exposed buccal threads, which were then covered with autogenous bone particles and small size granules of DBBM. The collagen membrane was stabilized with periosteal mattress suture. Six months postoperatively, CBCT images revealed a stable buccal bone layer at the implant site, indicating a successful GBR procedure. At this point in time, tooth 24 was atraumatically extracted. A ridge preservation was done utilizing DBBM, and a soft tissue graft form the tuber. A ceramic-metal FPD with excellent “white aesthetics” and a harmonic transition zone to the soft tissue was fabricated. At 3 years follow up, the peri-implant bone levels were stable, and the clinical outcomes were excellent. It is concluded that a GBR procedure, utilizing DBBM and a collagen barrier membrane with simultaneous implant placement, as well as ridge preservation using DBBM, are predictable therapeutic methods. However, gentle manipulation of the soft tissues, and wound stability, with tension-free passive closure of the wound margins are prerequisites for a long-term clinical success.

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