scholarly journals Estimation of Venous Blood Volume in the Dog by the Indicator-Dilution Method

1958 ◽  
Vol 6 (1) ◽  
pp. 55-59 ◽  
Author(s):  
W. R. MILNOR ◽  
C. A. BERTRAND
Keyword(s):  
Blood Volume ◽  
Venous Blood ◽  
Indicator Dilution ◽  
Dilution Method ◽  
Venous Blood Volume

Determination of central blood volume. Comparison of Stewart-Hamilton method with direct measurements in dogs

1959 ◽  
Vol 196 (3) ◽  
pp. 499-501 ◽  
Author(s):  
Robert C. Schlant ◽  
Paul Novack ◽  
William L. Kraus ◽  
Charles B. Moore ◽  
Florence W. Haynes ◽  
...  
Keyword(s):  
Cardiac Output ◽  
Blood Volume ◽  
Transit Time ◽  
Mean Transit Time ◽  
Total Radioactivity ◽  
Indicator Dilution ◽  
Dilution Method ◽  
Central Blood Volume ◽  
Volume Comparison ◽  
Direct Measurements

Central blood volume (cardiac output times mean transit time) from right atrium to ascending aorta was determined by the indicator-dilution method in 22 open-chested dogs which had previously had their red blood cells tagged with Cr51. The actual amount of blood in the heart and lungs was calculated from the total radioactivity in the blended homogenate of these organs. The two measurements of central blood volume correlated well ( r = +.88), the indicator-dilution volumes averaging 12% greater. The discrepancy between measurements is probably related to the pulmonary circuit having a lower hematocrit than the large vessels. The results substantiate the use of the Stewart-Hamilton formula (cardiac output times mean transit time) to measure central blood volume.

Detection of early central circulatory transits in patients with cirrhosis by gamma variate fit of indicator dilution profiles

2005 ◽  
Vol 288 (4) ◽  
pp. G677-G684 ◽  
Author(s):  
Jens H. Henriksen ◽  
Søren Møller ◽  
Stefan Fuglsang ◽  
Flemming Bendtsen
Keyword(s):  
Cardiac Output ◽  
Blood Volume ◽  
Indicator Dilution ◽  
Arterial Oxygen ◽  
Dilution Method ◽  
Gamma Variate ◽  
Arterial Blood ◽  
Flow Circulation ◽  
Cirrhotic Patients

Patients with cirrhosis have hyperdynamic circulation with abnormally distributed blood volume and widespread arteriovenous communications. We aimed to detect possible very early (i.e., before 4 s) and early (i.e., after 4 s) central circulatory transits and their potential influence on determination of central and arterial blood volume (CBV). Thirty-six cirrhotic patients and nineteen controls without liver disease undergoing hemodynamic catheterization were given central bolus injections of albumin with different labels. Exponential and gamma variate fits were applied to the indicator dilution curves, and the relations between flow, circulation times, and volumes were established according to kinetic principles. No significant very early central circulatory transits were identified. In contrast, early (i.e., 4 s to maximal) transits corresponding to a mean of 5.1% (vs. 0.8% in controls; P < 0.005) of cardiac output (equivalent to 0.36 vs. 0.05 l/min; P < 0.01) were found in cirrhotic patients. These early transits averaged 7.7 vs. 12.7 and 17.2 s of ordinary central transits of cirrhotic patients and controls, respectively ( P < 0.001). Early transits were directly correlated to the alveolar-arterial oxygen difference in the cirrhotic patients ( r = 0.46, P < 0.01) but not in controls ( r = 0.04; not significant). There was good agreement between the CBV determined by the conventional indicator dilution method and that determined by separation of early and ordinary transits by the gamma variate fit method (1.51 vs. 1.53 liter; not significant). In conclusion, no very early central circulatory transits were identified in cirrhotic patients. A significant part of the cardiac output undergoes an early transit, probably through pulmonary shunts or areas with low ventilation-perfusion ratios in cirrhotic patients. Composite determination of CBV by the gamma variate fit method is in close agreement with established kinetic methods. The study provides further evidence of abnormal central circulation in cirrhosis.

scholarly journals Quantifying cerebral hypoxia by near-infrared spectroscopy tissue oximetry: the role of arterial-to-venous blood volume ratio

2017 ◽  
Vol 22 (2) ◽  
pp. 025001 ◽  
Author(s):  
Martin B. Rasmussen ◽  
Vibeke R. Eriksen ◽  
Bjørn Andresen ◽  
Simon Hyttel-Sørensen ◽  
Gorm Greisen
Keyword(s):  
Infrared Spectroscopy ◽  
Blood Volume ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Venous Blood ◽  
Volume Ratio ◽  
Cerebral Hypoxia ◽  
Venous Blood Volume ◽  
Tissue Oximetry

scholarly journals Contributions of dynamic venous blood volume versus oxygenation level changes to BOLD fMRI

NeuroImage ◽  
2012 ◽  
Vol 60 (4) ◽  
pp. 2238-2246 ◽  
Author(s):  
Xiaopeng Zong ◽  
Tae Kim ◽  
Seong-Gi Kim
Keyword(s):  
Blood Volume ◽  
Venous Blood ◽  
Volume Versus ◽  
Bold Fmri ◽  
Oxygenation Level ◽  
Venous Blood Volume

scholarly journals Influence of Resting Venous Blood Volume Fraction on Dynamic Causal Modeling and System Identifiability

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Zhenghui Hu ◽  
Pengyu Ni ◽  
Qun Wan ◽  
Yan Zhang ◽  
Pengcheng Shi ◽  
...  
Keyword(s):  
Blood Volume ◽  
Volume Fraction ◽  
Venous Blood ◽  
Causal Modeling ◽  
Dynamic Causal Modeling ◽  
Venous Blood Volume

Extrajugular pathways of human cerebral venous blood drainage assessed by duplex ultrasound

2003 ◽  
Vol 94 (5) ◽  
pp. 1802-1805 ◽  
Author(s):  
Stephan J. Schreiber ◽  
Frank Lürtzing ◽  
Rainer Götze ◽  
Florian Doepp ◽  
Randolf Klingebiel ◽  
...  
Keyword(s):  
Blood Volume ◽  
Venous Blood ◽  
Duplex Ultrasound ◽  
Venous Drainage ◽  
Volume Flow ◽  
Venous System ◽  
Jugular Veins ◽  
Ultrasound Studies ◽  
Cerebral Venous Drainage ◽  
Venous Blood Volume

Cerebral venous drainage in humans is thought to be ensured mainly via the internal jugular veins (IJVs). However, anatomic, angiographic, and ultrasound studies suggest that the vertebral venous system serves as an important alternative drainage route. We assessed venous blood volume flow in vertebral veins (VVs) and IJVs of 12 healthy volunteers using duplex ultrasound. Measurements were performed at rest and during a transient bilateral IJV and a circular neck compression. Total venous blood volume flow at rest was 766 ± 226 ml/min (IJVs: 720 ± 232, VVs: 47 ± 33 ml/min). During bilateral IJV compression, VV flow increased to 128 ± 64 ml/min. Circular neck compression, causing an additional deep cervical vein obstruction, led to a further rise in VV volume flow (186 ± 70 ml/min). As the observed flow increase did not compensate for IJV flow cessation, other parts of the vertebral venous system, like the intraspinal epidural veins and the deep cervical veins, have to be considered as additional alternative drainage pathways.

Effects of dopamine on total peripheral resistance and integrated systemic venous blood volume in dogs

1980 ◽  
Vol 75 (5) ◽  
pp. 623-634 ◽  
Author(s):  
E. Grund ◽  
E. R. Müller-Ruchholtz ◽  
F. Hauer ◽  
E. R. Lapp
Keyword(s):  
Blood Volume ◽  
Total Peripheral Resistance ◽  
Venous Blood ◽  
Peripheral Resistance ◽  
Venous Blood Volume

Measuring venous blood volume changes during activation using hyperoxia

NeuroImage ◽  
2012 ◽  
Vol 59 (4) ◽  
pp. 3266-3274 ◽  
Author(s):  
N.P. Blockley ◽  
I.D. Driver ◽  
J.A. Fisher ◽  
S.T. Francis ◽  
P.A. Gowland
Keyword(s):  
Blood Volume ◽  
Venous Blood ◽  
Volume Changes ◽  
Venous Blood Volume

The analysis of the cerebral venous blood volume in cavernous sinus using 320 row multi-detector CT

2018 ◽  
Vol 167 ◽  
pp. 11-16 ◽  
Author(s):  
Katsuhiro Mizutani ◽  
Masahiro Toda ◽  
Yumi Yajima ◽  
Takenori Akiyama ◽  
Hirokazu Fujiwara ◽  
...  
Keyword(s):  
Blood Volume ◽  
Cavernous Sinus ◽  
Venous Blood ◽  
Venous Blood Volume
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