Changes of blood flow in the cerebral cortex after subcortical ischemic infarction.

Electroacupuncture (EA) is widely used to treat disorders of the nervous system, such as stroke. The aim of the present study was to investigate the effect of EA on cerebral blood flow (CBF) in cerebral ischemic rats. We developed an animal model of cerebral ischemia (CI) by occluding the blood flow of both common carotid arteries in Sprague-Dawley (SD) rats; 2 or 15 Hz EA was applied to both Zusanli acupoints. The levels of nitric oxide (NO) in the peripheral blood and amounts of calcitonin gene-related peptide (CGRP) in the cerebral cortex and thalamus were measured. In addition, L-N (G)-nitro arginine methyl ester (L-NAME) was used to measure the changes in CBF induced by EA in rats with and without CI. The results indicated that both 2 and 15 Hz EA increase the mean CBF in rats with and without CI. However, neither 2 nor 15 Hz EA induced changes in levels of NO in peripheral blood or changes in CGRP levels in cerebral cortex and thalamus. In addition, L-NAME did not change the increase in CBF. We concluded that both 2 and 15 Hz EA at both Zusanli acupoints induced the increase of CBF in rats with and without CI. Whether the effect of EA is related to NO or CGRP will be investigated in a future study.

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Measurement of Regional Blood Flow in Cerebral Cortex of Man Through Intact Skull

BMJ ◽

10.1136/bmj.1.5330.593 ◽

1963 ◽

Vol 1 (5330) ◽

pp. 593-593 ◽

Cited By ~ 54

Author(s):

H. I. Glass ◽

A. M. Harper

Keyword(s):

Blood Flow ◽

Cerebral Cortex ◽

Regional Blood Flow

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Frontal cerebral cortex blood flow, oxygen delivery and oxygenation during normoxic and hypoxic exercise in athletes

The Journal of Physiology ◽

10.1113/jphysiol.2011.210880 ◽

2011 ◽

Vol 589 (16) ◽

pp. 4027-4039 ◽

Cited By ~ 48

Author(s):

Ioannis Vogiatzis ◽

Zafeiris Louvaris ◽

Helmut Habazettl ◽

Dimitris Athanasopoulos ◽

Vasilis Andrianopoulos ◽

...

Keyword(s):

Blood Flow ◽

Cerebral Cortex ◽

Oxygen Delivery ◽

Frontal Cerebral Cortex ◽

Hypoxic Exercise

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FOCAL INCREASE OF BLOOD FLOW IN THE CEREBRAL CORTEX OF MAIN DURING VESTIBULAR STIMULATION

Brain ◽

10.1093/brain/108.3.609 ◽

1985 ◽

Vol 108 (3) ◽

pp. 609-623 ◽

Cited By ~ 109

Author(s):

LARS FRIBERG ◽

TOM S. OLSEN ◽

PER E. ROLAND ◽

OLAF B. PAULSON ◽

NIELS A. LASSEN

Keyword(s):

Blood Flow ◽

Cerebral Cortex ◽

Vestibular Stimulation

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Activity Distribution in the Cerebral Cortex in Organic Dementia as Revealed by Measurements of Regional Cerebral Blood Flow

Bayer-Symposium - Brain Function in Old Age ◽

10.1007/978-3-642-67304-7_18 ◽

1979 ◽

pp. 268-277 ◽

Cited By ~ 10

Author(s):

D. H. Ingvar ◽

N. A. Lassen

Keyword(s):

Blood Flow ◽

Cerebral Cortex ◽

Cerebral Blood Flow ◽

Regional Cerebral Blood Flow ◽

Regional Cerebral Blood ◽

Activity Distribution ◽

Organic Dementia

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Local Cerebral Blood Flow and Oxygen Consumption in Evolving Irreversible Ischemic Infarction

Positron Emission Tomography of the Brain ◽

10.1007/978-3-642-95428-3_15 ◽

1983 ◽

pp. 120-125 ◽

Cited By ~ 6

Author(s):

J. C. Baron ◽

D. Rougemont ◽

P. Lebrun-Grandié ◽

M. G. Bousser ◽

E. Cabanis ◽

...

Keyword(s):

Blood Flow ◽

Cerebral Blood Flow ◽

Oxygen Consumption ◽

Local Cerebral Blood Flow ◽

Ischemic Infarction

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Postnatal developmental changes in blood flow to choroid plexuses and cerebral cortex of the rat

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.1994.266.5.r1488 ◽

1994 ◽

Vol 266 (5) ◽

pp. R1488-R1492

Author(s):

J. Szmydynger-Chodobska ◽

A. Chodobski ◽

C. E. Johanson

Keyword(s):

Blood Flow ◽

Cerebral Cortex ◽

Vascular System ◽

Developmental Changes ◽

Choroidal Blood Flow ◽

Flow Rates ◽

Cortical Blood Flow ◽

Choroid Plexuses ◽

Choroidal Epithelium ◽

Cerebral Cortical Blood Flow

Postnatal developmental changes in blood flow to choroid plexuses of the lateral (LVCP) and fourth (4VCP) ventricles and cerebral cortex were studied in pentobarbital-anesthetized rats at 2, 3, 5, and 7-8 wk. Blood flow was measured by indicator fractionation with N-isopropyl-p-[125I]iodoamphetamine as the marker. Blood flow to the LVCP and 4VCP was 2.5 +/- 0.1 and 2.7 +/- 0.1 ml.g-1.min-1, respectively, and did not change between the 2nd and 3rd wk. However, it increased by 34% between the 3rd and 5th wk. From the age of 5 wk on, 4VCP was characterized by higher blood flow rates than LVCP. Cerebral cortical blood flow gradually increased between the 2nd and 5th wk. There was no difference in cortical blood flow between 5-wk-old and adult animals. The changes in choroidal blood flow likely represent a continuing adjustment of the choroidal vascular system to steadily increasing secretory capabilities of the maturing choroidal epithelium.

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