Magnetic Resonance Imaging of Regional Cerebral Blood Oxygenation Changes Under Acetazolamide in Carotid Occlusive Disease

Stroke ◽  
1995 ◽  
Vol 26 (1) ◽  
pp. 106-110 ◽  
Author(s):  
Andreas Kleinschmidt ◽  
Helmuth Steinmetz ◽  
Matthias Sitzer ◽  
Klaus-Dietmar Merboldt ◽  
Jens Frahm
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Blood Oxygenation ◽  
Occlusive Disease ◽  
Resonance Imaging ◽  
Regional Cerebral Blood ◽  
Carotid Occlusive Disease ◽  
Cerebral Blood Oxygenation

scholarly journals Simultaneous Recording of Cerebral Blood Oxygenation Changes during Human Brain Activation by Magnetic Resonance Imaging and Near-Infrared Spectroscopy

1996 ◽  
Vol 16 (5) ◽  
pp. 817-826 ◽  
Author(s):  
Andreas Kleinschmidt ◽  
Hellmuth Obrig ◽  
Martin Requardt ◽  
Klaus-Dietmar Merboldt ◽  
Ulrich Dirnagl ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Infrared Spectroscopy ◽  
Magnetic Resonance ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Simultaneous Recording ◽  
Blood Oxygenation ◽  
Resonance Imaging ◽  
Functional Studies ◽  
Cerebral Blood Oxygenation

Changes in cerebral blood oxygenation due to functional activation of the primary sensorimotor cortex during a unilateral finger opposition task were simultaneously mapped by deoxyhemoglobin-sensitive magnetic resonance imaging (MRI) and monitored by near-infrared spectroscopy (NIRS). Activation foci along the contralateral central sulcus displayed task-associated increases in MRI signal intensity, indicating a concomitant decrease of the focal concentration of deoxyhemoglobin. This interpretation was confirmed by simultaneous reductions in deoxyhemoglobin measured optically. Since observation of the latter effect required exact spatial matching of the MRI-detected activation foci and position of the fiber optic bundles (“optodes”) used for transmitting and receiving light, it may be concluded that optical recordings of changes in deoxyhemoglobin during functional challenge probe only a restricted brain tissue region. While deoxyhemoglobin responses seen by NIRS were smaller for ipsi- than for contralateral finger movements, task-related increases in oxyhemoglobin were rather similar between both conditions and, thus, seem to be less specific. Furthermore, no consistent changes were obtained for total hemoglobin during task performance, possibly due to the short timing of the repetitive protocol. In general, results underline, in humans, the hitherto assumed signal physiology for functional brain mapping by oxygenation-sensitive MRI and allow assessment of both constraints and practicability of functional studies by NIRS.

Magnetic Resonance Imaging of Angiographically Occult Runoff Vessels in Peripheral Arterial Occlusive Disease

1992 ◽  
Vol 326 (24) ◽  
pp. 1577-1581 ◽  
Author(s):  
Rodney S. Owen ◽  
Jeffrey P. Carpenter ◽  
Richard A. Baum ◽  
Leonard J. Perloff ◽  
Constantin Cope
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Resonance Imaging ◽  
Peripheral Arterial

A Quantitative Physiologic Model of Blood Oxygenation for Functional Magnetic Resonance Imaging

1995 ◽  
Vol 30 (11) ◽  
pp. 669-682 ◽  
Author(s):  
GASSER M. HATHOUT ◽  
SANJIV S. GAMBHIR ◽  
RAMESH K. GOPI ◽  
KONRAD A.T. KIRLEW ◽  
YONG CHOI ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Blood Oxygenation ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Physiologic Model
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