scholarly journals Left Ventricular Reverse Remodeling With Biventricular Versus Right Ventricular Pacing in Patients With Atrioventricular Block and Heart Failure in the BLOCK HF Trial

2015 ◽  
Vol 8 (3) ◽  
pp. 510-518 ◽  
Author(s):  
Martin St. John Sutton ◽  
Ted Plappert ◽  
Philip B. Adamson ◽  
Pei Li ◽  
Shelly A. Christman ◽  
...  
Keyword(s):  
Heart Failure ◽  
Right Ventricular ◽  
Atrioventricular Block ◽  
Left Ventricular ◽  
Reverse Remodeling ◽  
Ventricular Pacing ◽  
Right Ventricular Pacing ◽  
Left Ventricular Reverse Remodeling

scholarly journals Chronic Apical and Nonapical Right Ventricular Pacing in Patients with High-Grade Atrioventricular Block: Results of the Right Pace Study

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Carmine Muto ◽  
Valeria Calvi ◽  
Giovanni Luca Botto ◽  
Domenico Pecora ◽  
Daniele Porcelli ◽  
...  
Keyword(s):  
Heart Failure ◽  
Right Ventricular ◽  
Left Ventricular ◽  
Secondary Outcome ◽  
X Rays ◽  
Ventricular Pacing ◽  
Dual Chamber ◽  
Dual Chamber Pacemaker ◽  
Right Ventricular Pacing ◽  
The Right

Objective. The aim of the study was to compare the two approaches to chronic right ventricular pacing currently adopted in clinical practice: right ventricular apical (RVA) and non-RVA pacing. Background. Chronic RVA pacing is associated with an increased risk of atrial fibrillation, morbidity, and even mortality. Non-RVA pacing may yield more physiologic ventricular activation and provide potential long-term benefits and has recently been adopted as standard procedure at many implanting centers. Methods. The Right Pace study was a multicenter, prospective, single-blind, nonrandomized trial involving 437 patients indicated for dual-chamber pacemaker implantation with a high percentage of RV pacing. Results. RV lead-tip target location was the apex or the interventricular septum. RVA (274) and non-RVA patients (163) did not differ in baseline characteristics. During a median follow-up of 19 months (25th–75th percentiles, 13–25), 17 patients died. The rates of the primary outcome of death due to any cause or hospitalization for heart failure were comparable between the groups (log-rank test, p=0.609), as were the rates of the composite of death due to any cause, hospitalization for heart failure, or an increase in left ventricular end-systolic volume ≥ 15% as compared with the baseline evaluation (secondary outcome, p=0.703). After central adjudication of X-rays, comparison between adjudicated RVA (239 patients) and non-RVA (170 patients) confirmed the absence of difference in the rates of primary (p=0.402) and secondary (p=0.941) outcome. Conclusions. In patients with indications for dual-chamber pacemaker who require a high percentage of ventricular stimulation, RVA or non-RVA pacing resulted in comparable outcomes. This study is registered with ClinicalTrials.gov (identifier: NCT01647490).

scholarly journals New Onset Heart Failure after Right Ventricular Pacing in Patients with Normal Left Ventricular Function

2021 ◽  
Vol 10 (1) ◽  
pp. 365-369
Author(s):  
Fawad Qadir ◽  
Muhammad Shahid ◽  
Hadi Yousuf Saeed ◽  
Muhammad Tahir Mohyudin ◽  
Abu Bakar Ali Saad ◽  
...  
Keyword(s):  
Heart Failure ◽  
Right Ventricular ◽  
Left Ventricular ◽  
Lv Function ◽  
Av Block ◽  
Ventricular Pacing ◽  
Right Ventricular Pacing ◽  
Normal Left Ventricular ◽  
New Onset

Background: Cardiac pacing is the best optional treatment for cardiac rhythm disturbances such as cardiac arrhythmias, high grade atrioventricular (AV) block and heart failure (HF). Right ventricular apical (RVA) pacing in patients with normal left ventricular heart, may stimulate HF and cardiomyopathy. The objective of this study was to determine the frequency of new-onset heart failure after right ventricular apical pacing in patients having normal left ventricular (LV) function. Material and Methods: This prospective study was conducted from March 2017 to January 2019 in Chaudhry Pervaiz Elahi (CPE) Institute of Cardiology, Multan Pakistan. Adult patients (n=50) who fulfilled the American College of Cardiology (ACC) guidelines for permanent pacemaker (PPM) insertion and with normal LV function were included in this study. Pacemaker was implanted in all patients under local anesthesia. All patients were followed up for six months to determine the occurrence of heart failure. 2-D echocardiography was done to determine heart failure at follow up in pacemaker clinic. Results: Mean age of the study participants was 50.53 ± 6.75 years with male predominance. Mean pre-implantation ejection fraction (EF%) was 55.4 ± 4.2%. Main reason of PPM insertion was third degree AV block followed by right bundle branch block (RBBB). Incidence of HF was 4% at 06 months’ follow-up. Mortality occurred only in 1 (2%) patient. Conclusions: Right ventricular pacing is associated with risk of new onset heart failure in long term follow-up. In the present study, HF developed in 4% patients in a follow-up period of six months

scholarly journals Implications of QRS Duration in Dogs With Pacing-Induced Heart Failure

2011 ◽  
pp. 861-868 ◽  
Author(s):  
Y. WANG ◽  
X. GONG ◽  
Y. SU ◽  
J. CUI ◽  
X. SHU
Keyword(s):  
Heart Failure ◽  
Right Ventricular ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Left Ventricular Dyssynchrony ◽  
Ventricular Pacing ◽  
Right Ventricular Pacing ◽  
Ventricular Dyssynchrony ◽  
Rapid Pacing ◽  
Qrs Duration

The objective of this study was to find out the implication of QRS duration in dogs with rapid pacing-induced heart failure. Sixteen Beagle dogs were implanted with transvenous cardiac pacemakers and underwent rapid right ventricular pacing for 3 weeks at 260 bpm to induce heart failure. Dogs were divided into two groups according to the QRS duration: 9 with normal QRS duration (<100 ms) and 7 with prolonged QRS duration (≥100 ms). Cardiac systolic function and size was analyzed by real time 3-dimensional echocardiography and left ventricular dyssynchrony was assessed by speckle tracking strain imaging. Congestive heart failure developed 3 weeks after rapid right ventricular pacing. Dogs with prolonged QRS duration showed more extensive radial strain and circumferential strain dyssynchrony than dogs with normal QRS duration. At the end of 4-week recovery, greater improvement of left ventricular ejection fraction and left ventricular end-systolic volume was detected in dogs with normal QRS duration. The findings suggested that left ventricular dyssynchrony, indicated by a prolonged QRS duration, predicted an unsatisfying recovery in dogs with rapid pacing-induced heart failure. QRS duration had the potential to be a prognostic indicator for dogs with heart failure.

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